ENSG00000010165

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000361735 ENSG00000010165 No_inf pgwt_inf METTL13 protein_coding protein_coding 19.72421 14.50473 22.07607 0.6083833 1.027427 0.6056186 11.8344832 4.078943 15.7310845 1.6538473 1.0644154 1.944735 0.56530833 0.286100 0.71340 0.427300 0.78071066 0.02935686 FALSE  
ENST00000362019 ENSG00000010165 No_inf pgwt_inf METTL13 protein_coding protein_coding 19.72421 14.50473 22.07607 0.6083833 1.027427 0.6056186 0.7711530 0.000000 2.1409851 0.0000000 0.3854901 7.748854 0.03540000 0.000000 0.09955 0.099550 0.02935686 0.02935686 FALSE  
ENST00000367737 ENSG00000010165 No_inf pgwt_inf METTL13 protein_coding protein_coding 19.72421 14.50473 22.07607 0.6083833 1.027427 0.6056186 2.9089357 4.664814 0.5706454 0.4936524 0.5706454 -3.009180 0.16882500 0.320325 0.02330 -0.297025 0.06683500 0.02935686 FALSE  
ENST00000478330 ENSG00000010165 No_inf pgwt_inf METTL13 protein_coding protein_coding_CDS_not_defined 19.72421 14.50473 22.07607 0.6083833 1.027427 0.6056186 1.7557451 1.320222 1.9840225 0.2323030 0.4946325 0.584015 0.08631667 0.090275 0.08735 -0.002925 1.00000000 0.02935686 FALSE  
MSTRG.2246.3 ENSG00000010165 No_inf pgwt_inf METTL13 protein_coding   19.72421 14.50473 22.07607 0.6083833 1.027427 0.6056186 1.6617156 2.975759 1.3912379 1.8116917 0.9956791 -1.091396 0.09805000 0.202975 0.06365 -0.139325 0.99323661 0.02935686 FALSE  
MSTRG.2246.6 ENSG00000010165 No_inf pgwt_inf METTL13 protein_coding   19.72421 14.50473 22.07607 0.6083833 1.027427 0.6056186 0.6181653 1.464996 0.2580956 0.5281313 0.1594076 -2.459892 0.03939167 0.100350 0.01275 -0.087600 0.39314449 0.02935686 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000010165 E001 0.2285450 0.0154181301 0.452767067   1 171781660 171781663 4 + 0.142 0.000 -10.060
ENSG00000010165 E002 0.2285450 0.0154181301 0.452767067   1 171781664 171781673 10 + 0.142 0.000 -12.264
ENSG00000010165 E003 0.3415621 0.0391727298 0.235995675   1 171781674 171781681 8 + 0.199 0.000 -12.685
ENSG00000010165 E004 0.6834934 0.0360944172 0.041190107 0.22247846 1 171781682 171781695 14 + 0.335 0.000 -13.605
ENSG00000010165 E005 3.3339442 0.0045940894 0.280920751 0.60900074 1 171781696 171781737 42 + 0.689 0.540 -0.651
ENSG00000010165 E006 6.7985990 0.0021017215 0.178675121 0.49078484 1 171781738 171781795 58 + 0.943 0.796 -0.564
ENSG00000010165 E007 15.2678650 0.0010155573 0.038672790 0.21447803 1 171781796 171781987 192 + 1.266 1.105 -0.573
ENSG00000010165 E008 20.0989395 0.0007139144 0.593715356 0.83439153 1 171781988 171782120 133 + 1.306 1.336 0.107
ENSG00000010165 E009 37.9827232 0.0003861260 0.728676870 0.90095587 1 171783740 171784039 300 + 1.594 1.573 -0.069
ENSG00000010165 E010 35.0343808 0.0038106676 0.024738542 0.16436424 1 171784040 171784499 460 + 1.600 1.473 -0.434
ENSG00000010165 E011 4.3837652 0.0033478649 0.461576504 0.75538185 1 171785879 171785886 8 + 0.689 0.774 0.349
ENSG00000010165 E012 21.4920123 0.0006722694 0.292187687 0.62036790 1 171785887 171786078 192 + 1.375 1.304 -0.245
ENSG00000010165 E013 0.0000000       1 171786079 171786080 2 +      
ENSG00000010165 E014 17.2014409 0.0026962281 0.553032201 0.81259563 1 171787735 171787824 90 + 1.238 1.277 0.136
ENSG00000010165 E015 14.8962754 0.0029413594 0.607457415 0.84137773 1 171787825 171787862 38 + 1.181 1.216 0.125
ENSG00000010165 E016 16.9070656 0.0008456940 0.960797488 0.99069244 1 171787863 171787930 68 + 1.248 1.247 -0.001
ENSG00000010165 E017 27.3373826 0.0006055930 0.647690857 0.86152134 1 171790452 171790616 165 + 1.438 1.459 0.075
ENSG00000010165 E018 1.7020655 0.0081162408 0.733734850 0.90302932 1 171790617 171790925 309 + 0.407 0.455 0.256
ENSG00000010165 E019 28.8980842 0.0006031241 0.188004106 0.50233481 1 171792017 171792235 219 + 1.441 1.508 0.231
ENSG00000010165 E020 0.0000000       1 171794394 171794395 2 +      
ENSG00000010165 E021 22.8778498 0.0006873131 0.551481612 0.81164241 1 171794396 171794527 132 + 1.389 1.349 -0.140
ENSG00000010165 E022 89.2709927 0.0001792556 0.007893676 0.07939441 1 171796482 171797717 1236 + 1.918 1.990 0.240
ENSG00000010165 E023 0.0000000       1 171813875 171814023 149 +      

Help

Please Click HERE to learn more details about the results from DEXseq.