ENSG00000010610

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000011653 ENSG00000010610 No_inf pgwt_inf CD4 protein_coding protein_coding 74.72468 71.24315 67.6166 1.32674 1.529245 -0.07536298 55.30722 38.34025 61.747248 2.85255 1.918040 0.6873725 0.7412583 0.536675 0.915000 0.378325 0.14598444 0.04899369 FALSE TRUE
MSTRG.5915.12 ENSG00000010610 No_inf pgwt_inf CD4 protein_coding   74.72468 71.24315 67.6166 1.32674 1.529245 -0.07536298 16.15230 28.37713 2.571167 2.64043 2.571167 -3.4591419 0.2141167 0.400500 0.037075 -0.363425 0.04899369 0.04899369 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000010610 E001 0.0000000       12 6786858 6787005 148 +      
ENSG00000010610 E002 0.3431399 0.0272793333 9.701411e-02   12 6789489 6789513 25 + 0.243 0.000 -11.466
ENSG00000010610 E003 0.5715406 0.0294407153 1.929970e-02   12 6789514 6789527 14 + 0.352 0.000 -13.726
ENSG00000010610 E004 0.7202694 0.0354823211 3.937314e-01 7.068763e-01 12 6789528 6789535 8 + 0.301 0.170 -1.061
ENSG00000010610 E005 0.7202694 0.0354823211 3.937314e-01 7.068763e-01 12 6789536 6789536 1 + 0.301 0.170 -1.061
ENSG00000010610 E006 0.9486702 0.0808522986 1.635833e-01 4.680435e-01 12 6789537 6789539 3 + 0.398 0.170 -1.646
ENSG00000010610 E007 6.8659353 0.0020581981 3.318902e-02 1.956011e-01 12 6789540 6789567 28 + 1.000 0.781 -0.838
ENSG00000010610 E008 20.1835284 0.0007669808 4.954461e-02 2.462212e-01 12 6789568 6789662 95 + 1.389 1.261 -0.446
ENSG00000010610 E009 0.1316618 0.0122971158 5.607152e-01   12 6789802 6789840 39 + 0.000 0.093 10.630
ENSG00000010610 E010 0.6045171 0.0217589390 6.249998e-01   12 6798880 6799074 195 + 0.243 0.170 -0.646
ENSG00000010610 E011 0.2456120 0.0164172880 9.742379e-01   12 6799325 6799364 40 + 0.097 0.093 -0.061
ENSG00000010610 E012 1.6397151 0.0090757342 1.888130e-01 5.031283e-01 12 6799538 6799623 86 + 0.301 0.499 1.109
ENSG00000010610 E013 22.7342915 0.0006058640 3.532526e-02 2.030619e-01 12 6800072 6800187 116 + 1.439 1.310 -0.449
ENSG00000010610 E014 42.4890004 0.0003739405 7.434140e-02 3.097403e-01 12 6800307 6800471 165 + 1.679 1.598 -0.277
ENSG00000010610 E015 0.0000000       12 6813552 6813602 51 +      
ENSG00000010610 E016 0.1139502 0.0112061290 5.164012e-01   12 6814054 6814141 88 + 0.097 0.000 -11.684
ENSG00000010610 E017 47.7534585 0.0003048113 3.065858e-01 6.331900e-01 12 6814142 6814300 159 + 1.710 1.666 -0.150
ENSG00000010610 E018 1.5877941 0.0123613694 7.316651e-01 9.022531e-01 12 6814301 6814463 163 + 0.439 0.387 -0.283
ENSG00000010610 E019 0.8665265 0.2537230011 7.117901e-01 8.928904e-01 12 6814464 6814758 295 + 0.243 0.292 0.354
ENSG00000010610 E020 58.4132543 0.0013750994 2.102280e-02 1.486436e-01 12 6814759 6814992 234 + 1.821 1.726 -0.321
ENSG00000010610 E021 0.0000000       12 6814993 6815070 78 +      
ENSG00000010610 E022 2.3287901 0.0060523803 6.708709e-04 1.320499e-02 12 6815731 6816055 325 + 0.176 0.684 2.939
ENSG00000010610 E023 95.5527586 0.0001610295 4.599362e-03 5.490277e-02 12 6816056 6816403 348 + 2.027 1.942 -0.286
ENSG00000010610 E024 80.6230446 0.0002133096 9.098673e-02 3.464125e-01 12 6817130 6817330 201 + 1.940 1.884 -0.188
ENSG00000010610 E025 67.4779274 0.0002034858 7.332584e-02 3.074279e-01 12 6818421 6818542 122 + 1.868 1.803 -0.218
ENSG00000010610 E026 51.4100662 0.0003198871 2.652363e-01 5.932807e-01 12 6818847 6818914 68 + 1.742 1.696 -0.157
ENSG00000010610 E027 719.6858167 0.0000433835 4.475158e-13 7.494267e-11 12 6819299 6820812 1514 + 2.826 2.879 0.178

Help

Please Click HERE to learn more details about the results from DEXseq.