ENSG00000011523

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000377990 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding protein_coding 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.2705352 0.0000000 0.5266238 0.0000000 0.5266238 5.7458391 0.06635000 0.000000 0.135200 0.135200 0.99284725 0.01055749 FALSE TRUE
ENST00000475851 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding protein_coding 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.2526823 0.0000000 0.0000000 0.0000000 0.0000000 0.0000000 0.05692500 0.000000 0.000000 0.000000   0.01055749 FALSE TRUE
ENST00000703983 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding protein_coding 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.2823840 0.3864631 0.4606890 0.3864631 0.4606890 0.2475875 0.06001667 0.056575 0.123475 0.066900 1.00000000 0.01055749 FALSE TRUE
ENST00000703985 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding protein_coding 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.2798270 0.4279675 0.1539862 0.2600418 0.1539862 -1.4172490 0.05524167 0.070400 0.041275 -0.029125 0.99284725 0.01055749 FALSE TRUE
ENST00000704387 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding protein_coding 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.2665234 0.4828497 0.1185643 0.2853285 0.1185643 -1.9386573 0.05360833 0.085725 0.030450 -0.055275 0.99284725 0.01055749 FALSE TRUE
ENST00000704388 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding protein_coding 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.1671836 0.0000000 0.3316741 0.0000000 0.1916499 5.0945489 0.03697500 0.000000 0.072875 0.072875 0.92263992 0.01055749 FALSE TRUE
ENST00000704418 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding retained_intron 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.5830818 0.6593269 0.8054783 0.2908929 0.1078107 0.2849354 0.12500000 0.112225 0.193400 0.081175 0.99284725 0.01055749 FALSE FALSE
ENST00000704447 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding protein_coding 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.1356179 0.4068536 0.0000000 0.2368183 0.0000000 -5.3814689 0.02166667 0.065000 0.000000 -0.065000 0.99284725 0.01055749 FALSE TRUE
ENST00000704480 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding nonsense_mediated_decay 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.3252199 0.1946860 0.0000000 0.1946860 0.0000000 -4.3553406 0.07646667 0.035200 0.000000 -0.035200 0.99323661 0.01055749 TRUE TRUE
ENST00000704481 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding protein_coding 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.1369270 0.4107811 0.0000000 0.4107811 0.0000000 -5.3949980 0.02476667 0.074300 0.000000 -0.074300 0.99323661 0.01055749 FALSE TRUE
ENST00000704482 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding nonsense_mediated_decay 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.3572971 0.0000000 1.0718913 0.0000000 0.6190274 6.7574118 0.07850833 0.000000 0.235525 0.235525 0.93135618 0.01055749 TRUE TRUE
ENST00000704483 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding protein_coding_CDS_not_defined 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.6720944 2.0162831 0.0000000 0.3704993 0.0000000 -7.6626920 0.11228333 0.336850 0.000000 -0.336850 0.01055749 0.01055749   FALSE
ENST00000704643 ENSG00000011523 No_inf pgwt_inf CEP68 protein_coding protein_coding_CDS_not_defined 4.819843 5.939584 4.181877 0.3000898 0.2171045 -0.5051925 0.3939381 0.0000000 0.0000000 0.0000000 0.0000000 0.0000000 0.08806667 0.000000 0.000000 0.000000   0.01055749   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000011523 E001 0.0000000       2 65056354 65056361 8 +      
ENSG00000011523 E002 0.0000000       2 65056362 65056365 4 +      
ENSG00000011523 E003 0.0000000       2 65056366 65056371 6 +      
ENSG00000011523 E004 0.0000000       2 65056372 65056380 9 +      
ENSG00000011523 E005 0.0000000       2 65056381 65056382 2 +      
ENSG00000011523 E006 0.0000000       2 65056383 65056383 1 +      
ENSG00000011523 E007 0.0000000       2 65056384 65056394 11 +      
ENSG00000011523 E008 0.0000000       2 65056395 65056400 6 +      
ENSG00000011523 E009 0.0000000       2 65056401 65056403 3 +      
ENSG00000011523 E010 0.0000000       2 65056404 65056406 3 +      
ENSG00000011523 E011 0.0000000       2 65056407 65056409 3 +      
ENSG00000011523 E012 0.0000000       2 65056410 65056411 2 +      
ENSG00000011523 E013 0.0000000       2 65056412 65056415 4 +      
ENSG00000011523 E014 0.0000000       2 65056416 65056420 5 +      
ENSG00000011523 E015 0.0000000       2 65056421 65056425 5 +      
ENSG00000011523 E016 0.1138060 0.0112369555 4.978081e-01   2 65056426 65056431 6 + 0.102 0.000 -11.221
ENSG00000011523 E017 0.3417064 0.0205973506 8.948221e-02   2 65056432 65056445 14 + 0.254 0.000 -14.432
ENSG00000011523 E018 0.3417064 0.0205973506 8.948221e-02   2 65056446 65056451 6 + 0.254 0.000 -14.432
ENSG00000011523 E019 0.4558815 0.0160372133 3.731298e-02   2 65056452 65056460 9 + 0.314 0.000 -14.756
ENSG00000011523 E020 0.4558815 0.0160372133 3.731298e-02   2 65056461 65056464 4 + 0.314 0.000 -14.756
ENSG00000011523 E021 0.6846514 0.0138593706 7.146283e-03 7.459056e-02 2 65056465 65056524 60 + 0.413 0.000 -15.181
ENSG00000011523 E022 0.2283502 0.2594948988 2.709480e-01   2 65056525 65056528 4 + 0.184 0.000 -13.717
ENSG00000011523 E023 0.8507812 0.1395566133 6.665841e-01 8.706613e-01 2 65069399 65069431 33 + 0.314 0.225 -0.640
ENSG00000011523 E024 4.4293929 0.0033959489 1.567724e-02 1.238456e-01 2 65069432 65069801 370 + 0.882 0.570 -1.283
ENSG00000011523 E025 0.0000000       2 65069802 65069841 40 +      
ENSG00000011523 E026 0.7357494 0.0148746167 9.241775e-01 9.785119e-01 2 65070729 65071453 725 + 0.254 0.225 -0.224
ENSG00000011523 E027 19.3917974 0.0008928281 5.820410e-01 8.279047e-01 2 65071454 65072569 1116 + 1.341 1.276 -0.224
ENSG00000011523 E028 6.5145492 0.0023477073 8.713904e-01 9.595036e-01 2 65072570 65072883 314 + 0.896 0.852 -0.170
ENSG00000011523 E029 3.7926701 0.0149269533 7.131385e-01 8.935781e-01 2 65072884 65072980 97 + 0.719 0.643 -0.317
ENSG00000011523 E030 1.3587788 0.0108108772 8.683514e-01 9.580938e-01 2 65072981 65073935 955 + 0.366 0.373 0.039
ENSG00000011523 E031 0.4555123 0.0265066828 3.849620e-02   2 65073936 65074149 214 + 0.314 0.000 -14.743
ENSG00000011523 E032 0.3424952 0.0238700677 8.970046e-02   2 65074150 65074178 29 + 0.254 0.000 -14.428
ENSG00000011523 E033 0.3424952 0.0238700677 8.970046e-02   2 65074179 65074281 103 + 0.254 0.000 -14.428
ENSG00000011523 E034 3.1031791 0.0083305635 3.078752e-02 1.872826e-01 2 65074282 65074404 123 + 0.761 0.449 -1.394
ENSG00000011523 E035 0.7017990 0.1463524247 1.098540e-01 3.827137e-01 2 65074405 65074496 92 + 0.366 0.089 -2.546
ENSG00000011523 E036 1.8827064 0.0497957037 2.868837e-01 6.146819e-01 2 65074497 65075251 755 + 0.366 0.514 0.776
ENSG00000011523 E037 0.1308632 0.0126070997 5.805157e-01   2 65077042 65077044 3 + 0.000 0.089 11.513
ENSG00000011523 E038 1.6036553 0.0086433513 8.948641e-01 9.684250e-01 2 65077045 65077867 823 + 0.413 0.413 -0.002
ENSG00000011523 E039 0.9810632 0.0122711883 9.118441e-01 9.739511e-01 2 65077868 65077921 54 + 0.314 0.280 -0.224
ENSG00000011523 E040 1.2271047 0.0118724264 9.001531e-01 9.702448e-01 2 65077922 65077964 43 + 0.366 0.329 -0.224
ENSG00000011523 E041 3.0950142 0.0559643818 7.269663e-01 9.002120e-01 2 65080276 65081574 1299 + 0.592 0.620 0.124
ENSG00000011523 E042 0.8670421 0.0141009343 7.853236e-01 9.255765e-01 2 65082536 65082541 6 + 0.254 0.280 0.191
ENSG00000011523 E043 4.0891856 0.0422294022 8.239852e-02 3.281476e-01 2 65082542 65082709 168 + 0.834 0.570 -1.098
ENSG00000011523 E044 1.1315152 0.0117622224 3.794967e-01 6.962044e-01 2 65082710 65083638 929 + 0.254 0.373 0.776
ENSG00000011523 E045 59.1149339 0.0002841789 1.214459e-06 6.715705e-05 2 65083639 65087004 3366 + 1.710 1.817 0.361

Help

Please Click HERE to learn more details about the results from DEXseq.