ENSG00000030582

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000053867 ENSG00000030582 No_inf pgwt_inf GRN protein_coding protein_coding 526.3463 829.5129 405.3246 6.208403 3.961942 -1.033169 426.99881 668.12104 342.68165 10.123653 1.498254 -0.9632200 0.81269167 0.80560 0.845650 0.040050 9.928472e-01 7.637412e-09 FALSE  
ENST00000586242 ENSG00000030582 No_inf pgwt_inf GRN protein_coding protein_coding 526.3463 829.5129 405.3246 6.208403 3.961942 -1.033169 24.29256 67.74878 0.00000 12.402249 0.000000 -12.7261922 0.03178333 0.08145 0.000000 -0.081450 7.637412e-09 7.637412e-09 FALSE  
ENST00000588170 ENSG00000030582 No_inf pgwt_inf GRN protein_coding retained_intron 526.3463 829.5129 405.3246 6.208403 3.961942 -1.033169 42.56601 48.42978 42.33906 3.207493 1.897432 -0.1938627 0.08980000 0.05845 0.104425 0.045975 9.627454e-01 7.637412e-09 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000030582 E001 1.3928245 2.448145e-02 6.817945e-01 8.780203e-01 17 44345246 44345261 16 + 0.310 0.377 0.404
ENSG00000030582 E002 1.6553495 6.227415e-02 4.671666e-01 7.589983e-01 17 44345262 44345264 3 + 0.310 0.435 0.726
ENSG00000030582 E003 5.5556505 5.484586e-02 7.423358e-01 9.071948e-01 17 44345265 44345281 17 + 0.742 0.803 0.243
ENSG00000030582 E004 22.5576323 5.861760e-04 7.080637e-03 7.403638e-02 17 44345282 44345297 16 + 1.449 1.277 -0.596
ENSG00000030582 E005 22.9171283 5.801894e-04 4.783596e-03 5.641901e-02 17 44345298 44345301 4 + 1.459 1.281 -0.619
ENSG00000030582 E006 24.9471906 5.271381e-04 1.159765e-02 1.022879e-01 17 44345302 44345304 3 + 1.480 1.326 -0.533
ENSG00000030582 E007 26.9830275 4.904799e-04 2.434065e-02 1.626776e-01 17 44345305 44345305 1 + 1.499 1.366 -0.459
ENSG00000030582 E008 42.5088074 2.642335e-03 1.983805e-01 5.160595e-01 17 44345306 44345313 8 + 1.648 1.581 -0.229
ENSG00000030582 E009 108.1770020 1.458950e-04 6.594579e-01 8.668518e-01 17 44345314 44345334 21 + 2.011 1.997 -0.046
ENSG00000030582 E010 2.6532755 6.439550e-03 6.555567e-01 8.657366e-01 17 44345335 44345530 196 + 0.489 0.555 0.311
ENSG00000030582 E011 1.3922889 2.422842e-02 6.821670e-01 8.782694e-01 17 44345531 44345565 35 + 0.310 0.376 0.404
ENSG00000030582 E012 2.0946321 9.591044e-03 2.450308e-01 5.714909e-01 17 44345566 44345605 40 + 0.578 0.407 -0.841
ENSG00000030582 E013 2.0316627 6.993655e-03 4.823545e-01 7.692189e-01 17 44345610 44345741 132 + 0.378 0.487 0.574
ENSG00000030582 E014 0.6225922 2.149431e-01 7.845361e-01   17 44346089 44346228 140 + 0.229 0.181 -0.425
ENSG00000030582 E015 107.8110341 1.497252e-04 3.592014e-01 6.789253e-01 17 44349158 44349161 4 + 2.019 1.991 -0.096
ENSG00000030582 E016 109.8424780 1.467911e-04 4.143240e-01 7.218037e-01 17 44349162 44349164 3 + 2.025 2.000 -0.085
ENSG00000030582 E017 330.1940549 5.658733e-05 1.424255e-02 1.167691e-01 17 44349165 44349302 138 + 2.513 2.469 -0.144
ENSG00000030582 E018 0.7365378 1.436472e-02 4.001331e-01 7.117127e-01 17 44349303 44349425 123 + 0.310 0.181 -1.011
ENSG00000030582 E019 419.9031373 5.818234e-05 1.857829e-02 1.378981e-01 17 44349426 44349551 126 + 2.613 2.575 -0.123
ENSG00000030582 E020 0.7533137 4.148668e-02 9.943003e-01 1.000000e+00 17 44349552 44349624 73 + 0.229 0.228 -0.011
ENSG00000030582 E021 0.6397908 1.493000e-02 5.374562e-01   17 44349625 44349666 42 + 0.130 0.228 0.989
ENSG00000030582 E022 380.8095777 6.076085e-05 2.455685e-01 5.720412e-01 17 44349667 44349751 85 + 2.558 2.539 -0.064
ENSG00000030582 E023 1.2276809 1.090688e-02 2.784851e-01 6.065091e-01 17 44349752 44349894 143 + 0.437 0.270 -1.011
ENSG00000030582 E024 380.5868803 8.482517e-04 3.670466e-01 6.858030e-01 17 44350228 44350288 61 + 2.557 2.539 -0.061
ENSG00000030582 E025 360.8275450 5.413760e-05 1.174035e-01 3.966197e-01 17 44350289 44350340 52 + 2.540 2.513 -0.089
ENSG00000030582 E026 240.6932460 7.652730e-05 8.380418e-02 3.311178e-01 17 44350442 44350461 20 + 2.371 2.335 -0.120
ENSG00000030582 E027 382.2281396 3.163494e-04 1.729760e-01 4.821784e-01 17 44350462 44350538 77 + 2.563 2.539 -0.081
ENSG00000030582 E028 262.0202479 4.208761e-04 1.825821e-01 4.954026e-01 17 44350539 44350577 39 + 2.403 2.374 -0.095
ENSG00000030582 E029 362.2597396 4.241703e-04 1.739994e-01 4.836849e-01 17 44350691 44350771 81 + 2.541 2.515 -0.085
ENSG00000030582 E030 277.4012524 6.611730e-05 2.539539e-01 5.810446e-01 17 44350772 44350800 29 + 2.392 2.414 0.075
ENSG00000030582 E031 1.2280594 1.102267e-02 2.786257e-01 6.067158e-01 17 44350911 44351036 126 + 0.437 0.270 -1.011
ENSG00000030582 E032 377.7051757 5.383426e-05 9.955522e-01 1.000000e+00 17 44351037 44351100 64 + 2.541 2.541 0.000
ENSG00000030582 E033 340.6088277 5.908701e-04 2.765737e-01 6.046285e-01 17 44351101 44351163 63 + 2.511 2.490 -0.072
ENSG00000030582 E034 6.8642038 3.845281e-03 1.534603e-01 4.534702e-01 17 44351164 44351362 199 + 0.742 0.907 0.646
ENSG00000030582 E035 451.9958519 6.024325e-05 2.408128e-01 5.668730e-01 17 44351363 44351460 98 + 2.631 2.613 -0.059
ENSG00000030582 E036 815.2901573 3.682917e-05 3.227548e-01 6.473115e-01 17 44351550 44351752 203 + 2.867 2.878 0.037
ENSG00000030582 E037 361.6025357 6.479022e-05 2.439178e-01 5.702255e-01 17 44351753 44351795 43 + 2.508 2.528 0.067
ENSG00000030582 E038 755.2424197 7.772043e-04 3.508344e-01 6.711977e-01 17 44352015 44352201 187 + 2.831 2.846 0.050
ENSG00000030582 E039 339.4168102 6.026305e-05 1.063397e-01 3.765498e-01 17 44352202 44352248 47 + 2.474 2.503 0.096
ENSG00000030582 E040 917.2015912 3.523443e-05 8.148169e-03 8.118500e-02 17 44352341 44352528 188 + 2.906 2.934 0.094
ENSG00000030582 E041 501.5142559 7.502626e-05 4.259648e-01 7.304687e-01 17 44352529 44352571 43 + 2.672 2.660 -0.039
ENSG00000030582 E042 2.1656205 2.013696e-02 4.009389e-01 7.122064e-01 17 44352572 44352660 89 + 0.378 0.511 0.689
ENSG00000030582 E043 444.8620212 4.973368e-05 4.825358e-01 7.693827e-01 17 44352661 44352715 55 + 2.604 2.615 0.036
ENSG00000030582 E044 1149.8094628 4.217767e-05 2.981587e-09 2.831494e-07 17 44352716 44353106 391 + 2.983 3.040 0.189

Help

Please Click HERE to learn more details about the results from DEXseq.