ENSG00000033178

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000322244 ENSG00000033178 No_inf pgwt_inf UBA6 protein_coding protein_coding 25.65143 12.51295 34.89364 1.683484 2.910247 1.478803 0.9108109 1.025131 0.7401555 0.09013376 0.0169774 -0.4645515 0.04680833 0.085325 0.021700 -0.063625 6.204052e-01 1.086678e-05 FALSE TRUE
ENST00000506571 ENSG00000033178 No_inf pgwt_inf UBA6 protein_coding retained_intron 25.65143 12.51295 34.89364 1.683484 2.910247 1.478803 7.0180428 0.000000 12.2689987 0.00000000 1.3319884 10.2619772 0.21435000 0.000000 0.350825 0.350825 1.086678e-05 1.086678e-05 FALSE TRUE
ENST00000514261 ENSG00000033178 No_inf pgwt_inf UBA6 protein_coding nonsense_mediated_decay 25.65143 12.51295 34.89364 1.683484 2.910247 1.478803 1.6578909 1.611654 3.3620181 1.61165450 1.4002505 1.0561458 0.06001667 0.091850 0.088200 -0.003650 9.928472e-01 1.086678e-05 TRUE FALSE
MSTRG.21860.2 ENSG00000033178 No_inf pgwt_inf UBA6 protein_coding   25.65143 12.51295 34.89364 1.683484 2.910247 1.478803 14.1058968 8.721238 16.0289145 0.22033486 0.2619086 0.8773184 0.59886667 0.728350 0.469950 -0.258400 8.178413e-01 1.086678e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000033178 E001 14.7651446 0.0009742749 3.443447e-06 0.0001667873 4 67612652 67616348 3697 - 1.014 1.365 1.251
ENSG00000033178 E002 215.4714189 0.0025178674 6.671437e-02 0.2923738142 4 67616349 67618854 2506 - 2.308 2.352 0.147
ENSG00000033178 E003 38.6265631 0.0003816177 7.535186e-01 0.9119956853 4 67618855 67619132 278 - 1.593 1.583 -0.035
ENSG00000033178 E004 18.3141657 0.0126398112 3.239248e-01 0.6482178498 4 67622831 67622925 95 - 1.241 1.328 0.305
ENSG00000033178 E005 13.6518155 0.0010935857 6.654387e-01 0.8701285254 4 67623135 67623222 88 - 1.142 1.180 0.138
ENSG00000033178 E006 13.2103172 0.0017748758 3.572018e-01 0.6772290841 4 67624126 67624253 128 - 1.112 1.190 0.279
ENSG00000033178 E007 16.6575199 0.0008722616 7.252740e-01 0.8993611560 4 67624994 67625187 194 - 1.226 1.256 0.105
ENSG00000033178 E008 11.9608545 0.0011533199 2.998142e-01 0.6270919367 4 67626360 67626477 118 - 1.136 1.053 -0.301
ENSG00000033178 E009 5.9277948 0.0294925688 1.446557e-01 0.4400682376 4 67629071 67629092 22 - 0.897 0.714 -0.722
ENSG00000033178 E010 6.1741317 0.0026658408 1.280738e-01 0.4149843745 4 67629093 67629105 13 - 0.908 0.741 -0.654
ENSG00000033178 E011 8.4525588 0.0298668559 8.355501e-01 0.9451287992 4 67629106 67629142 37 - 0.955 0.986 0.116
ENSG00000033178 E012 0.0000000       4 67630454 67630465 12 -      
ENSG00000033178 E013 11.3494732 0.0028026109 7.971775e-01 0.9301739772 4 67630466 67630535 70 - 1.072 1.100 0.099
ENSG00000033178 E014 10.3126766 0.0016144101 5.333218e-01 0.8008554204 4 67631708 67631771 64 - 1.065 1.014 -0.188
ENSG00000033178 E015 10.3308902 0.0144520247 7.374328e-01 0.9047428208 4 67631857 67631908 52 - 1.058 1.027 -0.114
ENSG00000033178 E016 12.3575992 0.0011509846 5.294286e-01 0.7983310625 4 67633345 67633473 129 - 1.136 1.088 -0.171
ENSG00000033178 E017 10.5257068 0.0013496822 3.137301e-01 0.6396672108 4 67634242 67634322 81 - 1.086 1.000 -0.313
ENSG00000033178 E018 13.4091308 0.0010316411 6.997878e-01 0.8866306482 4 67634429 67634518 90 - 1.136 1.171 0.126
ENSG00000033178 E019 12.4434691 0.0011152724 6.956255e-01 0.8842642940 4 67635453 67635558 106 - 1.105 1.142 0.131
ENSG00000033178 E020 13.9514814 0.0009924838 2.929156e-01 0.6212650378 4 67638943 67639124 182 - 1.130 1.216 0.306
ENSG00000033178 E021 9.5210010 0.0014415190 9.885312e-02 0.3625365561 4 67641151 67641228 78 - 0.946 1.100 0.564
ENSG00000033178 E022 7.8273938 0.0019481824 9.950148e-01 1.0000000000 4 67644698 67644778 81 - 0.937 0.940 0.014
ENSG00000033178 E023 6.9963489 0.0865668693 9.441959e-01 0.9859999798 4 67645938 67646016 79 - 0.887 0.907 0.077
ENSG00000033178 E024 6.9474963 0.0029046384 5.078410e-01 0.7854572534 4 67646724 67646791 68 - 0.917 0.852 -0.251
ENSG00000033178 E025 9.9457135 0.0015768592 2.008759e-02 0.1446108403 4 67649068 67649211 144 - 1.105 0.889 -0.798
ENSG00000033178 E026 0.6848257 0.4334932954 1.930702e-01 0.5087775455 4 67661663 67662188 526 - 0.326 0.000 -10.311
ENSG00000033178 E027 4.6999474 0.0032661637 2.116668e-02 0.1492285139 4 67662189 67662255 67 - 0.843 0.553 -1.213
ENSG00000033178 E028 0.4907111 0.0894156347 6.059391e-01   4 67662256 67662261 6 - 0.138 0.216 0.787
ENSG00000033178 E029 1.8672937 0.2108773434 2.113399e-01 0.5326746024 4 67662487 67663138 652 - 0.326 0.590 1.371
ENSG00000033178 E030 5.2244836 0.0255848445 2.296144e-01 0.5550181475 4 67663139 67663215 77 - 0.843 0.687 -0.628
ENSG00000033178 E031 2.4023294 0.0072928593 8.572107e-01 0.9539620623 4 67663216 67663884 669 - 0.534 0.512 -0.106
ENSG00000033178 E032 4.0879093 0.0034802049 8.408790e-01 0.9474255854 4 67663885 67663947 63 - 0.708 0.687 -0.088
ENSG00000033178 E033 4.9547144 0.0028471044 7.875436e-01 0.9263762566 4 67665189 67665292 104 - 0.753 0.789 0.143
ENSG00000033178 E034 7.8139117 0.0217965336 8.171638e-01 0.9374179991 4 67668551 67668674 124 - 0.946 0.924 -0.082
ENSG00000033178 E035 8.3087094 0.0020610036 9.002646e-01 0.9703019414 4 67670470 67670592 123 - 0.964 0.956 -0.029
ENSG00000033178 E036 6.2452646 0.0025545492 7.270761e-01 0.9002722016 4 67673697 67673777 81 - 0.866 0.832 -0.131
ENSG00000033178 E037 7.1211047 0.0022161861 9.345635e-02 0.3514859284 4 67677611 67677722 112 - 0.964 0.789 -0.673
ENSG00000033178 E038 0.0000000       4 67678430 67678438 9 -      
ENSG00000033178 E039 6.7271066 0.0029727965 2.344300e-02 0.1590612009 4 67678439 67678533 95 - 0.964 0.714 -0.972
ENSG00000033178 E040 4.6510585 0.0029993506 5.558517e-04 0.0114150659 4 67681563 67681591 29 - 0.876 0.416 -2.021
ENSG00000033178 E041 5.6146249 0.0024056698 2.111535e-03 0.0316419414 4 67682119 67682213 95 - 0.927 0.553 -1.535
ENSG00000033178 E042 2.7900543 0.0051053589 7.601555e-03 0.0775615078 4 67696645 67696707 63 - 0.691 0.293 -2.021
ENSG00000033178 E043 2.4646289 0.0061585161 7.718624e-02 0.3165115179 4 67701049 67701155 107 - 0.620 0.359 -1.301

Help

Please Click HERE to learn more details about the results from DEXseq.