ENSG00000050130

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000425728 ENSG00000050130 No_inf pgwt_inf JKAMP protein_coding protein_coding 45.00066 35.15129 48.92233 1.017593 1.118024 0.4767997 4.118417 1.323474 6.413340 1.0066176 2.2344370 2.268134 0.08698333 0.035525 0.134025 0.098500 9.928472e-01 2.309361e-05 FALSE TRUE
ENST00000553156 ENSG00000050130 No_inf pgwt_inf JKAMP protein_coding retained_intron 45.00066 35.15129 48.92233 1.017593 1.118024 0.4767997 2.805022 4.070499 2.416717 0.7039194 0.5528638 -0.749740 0.06759167 0.116675 0.048750 -0.067925 9.300585e-01 2.309361e-05   FALSE
ENST00000553941 ENSG00000050130 No_inf pgwt_inf JKAMP protein_coding retained_intron 45.00066 35.15129 48.92233 1.017593 1.118024 0.4767997 1.763320 3.216293 1.556571 1.9893672 0.8519939 -1.042267 0.04465833 0.092300 0.031300 -0.061000 1.000000e+00 2.309361e-05 FALSE TRUE
ENST00000554754 ENSG00000050130 No_inf pgwt_inf JKAMP protein_coding protein_coding_CDS_not_defined 45.00066 35.15129 48.92233 1.017593 1.118024 0.4767997 2.773155 6.704666 0.000000 1.7690976 0.0000000 -9.391172 0.07520000 0.193025 0.000000 -0.193025 2.309361e-05 2.309361e-05 TRUE FALSE
ENST00000554795 ENSG00000050130 No_inf pgwt_inf JKAMP protein_coding protein_coding 45.00066 35.15129 48.92233 1.017593 1.118024 0.4767997 8.608042 1.374607 13.101836 1.3746068 3.4897644 3.243322 0.17719167 0.039425 0.269225 0.229800 2.270673e-01 2.309361e-05 FALSE FALSE
ENST00000557560 ENSG00000050130 No_inf pgwt_inf JKAMP protein_coding protein_coding_CDS_not_defined 45.00066 35.15129 48.92233 1.017593 1.118024 0.4767997 1.091805 1.866975 0.000000 1.8669753 0.0000000 -7.552266 0.02693333 0.053575 0.000000 -0.053575 9.928472e-01 2.309361e-05 FALSE FALSE
ENST00000616435 ENSG00000050130 No_inf pgwt_inf JKAMP protein_coding protein_coding 45.00066 35.15129 48.92233 1.017593 1.118024 0.4767997 16.809714 8.127546 16.524960 1.5768233 2.3819854 1.022854 0.35786667 0.233375 0.335250 0.101875 9.928472e-01 2.309361e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000050130 E001 0.0000000       14 59484443 59484444 2 +      
ENSG00000050130 E002 0.5251085 0.1892103213 3.179304e-02   14 59484445 59484491 47 + 0.000 0.342 11.210
ENSG00000050130 E003 1.1813797 0.0108571500 1.343745e-04 0.003730860 14 59484492 59484502 11 + 0.000 0.568 14.607
ENSG00000050130 E004 1.4437579 0.0097098720 2.076368e-05 0.000795282 14 59484503 59484516 14 + 0.000 0.633 14.869
ENSG00000050130 E005 3.5055923 0.0045586414 1.175522e-02 0.103146719 14 59484517 59484527 11 + 0.477 0.806 1.429
ENSG00000050130 E006 4.5497096 0.0037782791 1.831266e-01 0.496043425 14 59484528 59484530 3 + 0.663 0.825 0.659
ENSG00000050130 E007 5.5935411 0.0042255009 6.731288e-01 0.873614937 14 59484531 59484536 6 + 0.793 0.844 0.203
ENSG00000050130 E008 6.1808469 0.0114938037 9.090261e-01 0.973149985 14 59484537 59484544 8 + 0.845 0.863 0.067
ENSG00000050130 E009 7.6692208 0.0641434427 6.200965e-01 0.847452444 14 59484545 59484559 15 + 0.903 0.972 0.259
ENSG00000050130 E010 7.8812117 0.0569426871 8.597115e-01 0.954778087 14 59484560 59484568 9 + 0.935 0.958 0.088
ENSG00000050130 E011 9.9867310 0.0732739327 6.840766e-01 0.879380320 14 59484569 59484593 25 + 1.065 0.999 -0.240
ENSG00000050130 E012 5.6763954 0.0025426280 5.803346e-02 0.270195088 14 59484594 59484989 396 + 0.716 0.929 0.833
ENSG00000050130 E013 3.0906768 0.1051945246 2.887016e-01 0.616195517 14 59484990 59485116 127 + 0.505 0.715 0.929
ENSG00000050130 E014 4.0931652 0.0132931968 5.680924e-02 0.266521129 14 59485465 59485968 504 + 0.580 0.825 1.022
ENSG00000050130 E015 1.4717032 0.0584480682 5.468738e-01 0.809015805 14 59486681 59486712 32 + 0.343 0.447 0.581
ENSG00000050130 E016 8.9440201 0.0231291927 8.738942e-01 0.960415031 14 59486713 59486730 18 + 1.000 0.986 -0.053
ENSG00000050130 E017 21.3009050 0.0007658424 2.465616e-01 0.573172691 14 59486731 59486804 74 + 1.373 1.305 -0.239
ENSG00000050130 E018 6.3163028 0.0022600576 1.850599e-02 0.137618718 14 59487194 59487673 480 + 0.733 0.986 0.980
ENSG00000050130 E019 47.4334235 0.0003171275 8.937628e-01 0.967867763 14 59487674 59487828 155 + 1.682 1.681 -0.001
ENSG00000050130 E020 26.7039086 0.0007831538 6.561648e-01 0.865823662 14 59495018 59495087 70 + 1.447 1.427 -0.069
ENSG00000050130 E021 38.5795274 0.0004831192 2.802047e-01 0.608306864 14 59495088 59495224 137 + 1.613 1.567 -0.156
ENSG00000050130 E022 0.0000000       14 59495225 59495305 81 +      
ENSG00000050130 E023 47.0176182 0.0105797195 3.838586e-01 0.699510375 14 59498727 59498908 182 + 1.698 1.651 -0.160
ENSG00000050130 E024 1.7330725 0.0084050142 2.121390e-01 0.533852072 14 59500882 59501190 309 + 0.343 0.531 0.996
ENSG00000050130 E025 27.9747100 0.0022408155 8.528492e-02 0.334325467 14 59501191 59501267 77 + 1.497 1.402 -0.327
ENSG00000050130 E026 154.0892764 0.0001299885 5.634503e-01 0.817740736 14 59503854 59505410 1557 + 2.190 2.183 -0.021

Help

Please Click HERE to learn more details about the results from DEXseq.