ENSG00000057252

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000367619 ENSG00000057252 No_inf pgwt_inf SOAT1 protein_coding protein_coding 18.9385 9.460237 23.31974 0.2947431 0.8723456 1.300698 9.2355916 7.8633153 9.810160 0.6926367 1.0606623 0.3187753 0.55865000 0.830400 0.424350 -0.406050 5.084084e-01 2.375876e-05 FALSE TRUE
ENST00000426956 ENSG00000057252 No_inf pgwt_inf SOAT1 protein_coding protein_coding 18.9385 9.460237 23.31974 0.2947431 0.8723456 1.300698 6.0958718 0.0000000 9.201116 0.0000000 0.9950369 9.8472322 0.25594167 0.000000 0.391450 0.391450 2.375876e-05 2.375876e-05 FALSE FALSE
ENST00000539888 ENSG00000057252 No_inf pgwt_inf SOAT1 protein_coding protein_coding 18.9385 9.460237 23.31974 0.2947431 0.8723456 1.300698 0.2511809 0.6084280 0.000000 0.6084280 0.0000000 -5.9505337 0.02243333 0.061375 0.000000 -0.061375 9.928472e-01 2.375876e-05 FALSE TRUE
ENST00000540564 ENSG00000057252 No_inf pgwt_inf SOAT1 protein_coding protein_coding 18.9385 9.460237 23.31974 0.2947431 0.8723456 1.300698 3.1266175 0.3007833 4.308465 0.3007833 0.8958001 3.7965378 0.13755833 0.032025 0.184175 0.152150 4.321122e-01 2.375876e-05 FALSE TRUE
MSTRG.2335.3 ENSG00000057252 No_inf pgwt_inf SOAT1 protein_coding   18.9385 9.460237 23.31974 0.2947431 0.8723456 1.300698 0.2292368 0.6877105 0.000000 0.3980821 0.0000000 -6.1245566 0.02540000 0.076200 0.000000 -0.076200 8.057819e-01 2.375876e-05 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000057252 E001 0.7016252 1.377395e-02 2.540895e-01 5.811645e-01 1 179293714 179293782 69 + 0.294 0.117 -1.648
ENSG00000057252 E002 1.5512586 8.688089e-03 5.662525e-01 8.190445e-01 1 179293783 179293796 14 + 0.438 0.350 -0.496
ENSG00000057252 E003 7.9119652 1.754711e-03 3.889175e-01 7.025792e-01 1 179293797 179293936 140 + 0.979 0.892 -0.326
ENSG00000057252 E004 0.1141751 1.119515e-02 8.992909e-01   1 179294320 179294401 82 + 0.077 0.000 -8.310
ENSG00000057252 E005 12.8340528 1.091983e-03 3.013307e-01 6.287415e-01 1 179302677 179302802 126 + 1.169 1.084 -0.306
ENSG00000057252 E006 10.3138448 1.623797e-03 3.646014e-01 6.835681e-01 1 179323437 179323495 59 + 1.081 0.999 -0.301
ENSG00000057252 E007 18.8273463 1.029444e-03 2.207641e-01 5.445351e-01 1 179335506 179335657 152 + 1.325 1.240 -0.298
ENSG00000057252 E008 14.8355191 9.555463e-04 1.496099e-01 4.473214e-01 1 179337837 179337896 60 + 1.238 1.126 -0.396
ENSG00000057252 E009 18.8872099 9.998063e-03 1.193296e-01 3.996046e-01 1 179339438 179339545 108 + 1.341 1.217 -0.437
ENSG00000057252 E010 34.6112581 2.385413e-03 2.511741e-01 5.781983e-01 1 179341028 179341310 283 + 1.571 1.508 -0.214
ENSG00000057252 E011 16.2347354 1.421583e-03 4.866363e-01 7.723939e-01 1 179342114 179342192 79 + 1.252 1.200 -0.184
ENSG00000057252 E012 18.5847666 7.007184e-04 2.010889e-01 5.198872e-01 1 179342862 179342943 82 + 1.321 1.233 -0.312
ENSG00000057252 E013 12.8651072 3.352516e-03 5.402706e-01 8.052108e-01 1 179343590 179343635 46 + 1.158 1.106 -0.186
ENSG00000057252 E014 25.1939169 1.590684e-03 2.177039e-02 1.516870e-01 1 179344947 179345076 130 + 1.467 1.324 -0.493
ENSG00000057252 E015 22.3433520 6.300679e-04 3.151743e-01 6.411331e-01 1 179347600 179347697 98 + 1.388 1.324 -0.222
ENSG00000057252 E016 21.9792384 1.004333e-02 3.405622e-01 6.625854e-01 1 179348844 179348942 99 + 1.325 1.395 0.241
ENSG00000057252 E017 24.5451490 6.044572e-03 1.172366e-01 3.962324e-01 1 179350296 179350431 136 + 1.443 1.337 -0.368
ENSG00000057252 E018 10.4262647 1.348874e-03 3.211558e-01 6.458153e-01 1 179351317 179351344 28 + 1.088 0.999 -0.326
ENSG00000057252 E019 24.6942469 7.790926e-04 1.363664e-01 4.278307e-01 1 179351345 179351462 118 + 1.440 1.349 -0.315
ENSG00000057252 E020 270.4916188 8.926147e-05 1.580493e-10 1.804345e-08 1 179353585 179358680 5096 + 2.390 2.476 0.287

Help

Please Click HERE to learn more details about the results from DEXseq.