ENSG00000058335

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000559926 ENSG00000058335 No_inf pgwt_inf RASGRF1 protein_coding protein_coding_CDS_not_defined 29.55931 9.022905 48.74477 0.2007562 1.443878 2.432281 0.2634497 0.7903491 0.000000 0.4676908 0.0000000 -6.322558 0.0285000 0.085500 0.000000 -0.08550 0.53920459 0.02234779   FALSE
ENST00000623620 ENSG00000058335 No_inf pgwt_inf RASGRF1 protein_coding TEC 29.55931 9.022905 48.74477 0.2007562 1.443878 2.432281 6.8172276 1.5463535 11.731545 0.1452909 0.5829285 2.915381 0.2155083 0.170600 0.240300 0.06970 0.99284725 0.02234779 FALSE FALSE
MSTRG.10047.13 ENSG00000058335 No_inf pgwt_inf RASGRF1 protein_coding   29.55931 9.022905 48.74477 0.2007562 1.443878 2.432281 4.0382233 0.0000000 7.145527 0.0000000 1.6358877 9.482914 0.0983750 0.000000 0.145800 0.14580 0.02234779 0.02234779 FALSE TRUE
MSTRG.10047.3 ENSG00000058335 No_inf pgwt_inf RASGRF1 protein_coding   29.55931 9.022905 48.74477 0.2007562 1.443878 2.432281 8.3014298 4.1244525 11.410524 0.6606177 1.1761125 1.465861 0.3387833 0.461225 0.235875 -0.22535 0.92761938 0.02234779 FALSE TRUE
MSTRG.10047.4 ENSG00000058335 No_inf pgwt_inf RASGRF1 protein_coding   29.55931 9.022905 48.74477 0.2007562 1.443878 2.432281 6.6706060 1.7831387 11.281798 0.6515175 0.6351030 2.654716 0.2138000 0.194725 0.231625 0.03690 0.99284725 0.02234779 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000058335 E001 0.0000000       15 78959906 78959946 41 -      
ENSG00000058335 E002 0.3591269 0.1990625372 4.252547e-01   15 78959947 78960784 838 - 0.086 0.190 1.338
ENSG00000058335 E003 2.2560147 0.0158516975 3.059011e-01 6.326823e-01 15 78960785 78960978 194 - 0.402 0.574 0.852
ENSG00000058335 E004 78.1362923 0.0074202807 8.168467e-04 1.536065e-02 15 78960979 78961941 963 - 1.754 1.922 0.566
ENSG00000058335 E005 32.8694205 0.0004076897 3.644870e-02 2.073267e-01 15 78961942 78962236 295 - 1.395 1.532 0.470
ENSG00000058335 E006 11.0535462 0.0029446188 3.938074e-01 7.068896e-01 15 78971866 78971902 37 - 0.962 1.059 0.357
ENSG00000058335 E007 12.0018287 0.0012718104 3.182260e-01 6.436606e-01 15 78971903 78971934 32 - 0.992 1.099 0.390
ENSG00000058335 E008 17.7999407 0.0007874562 1.053601e-01 3.747001e-01 15 78973303 78973420 118 - 1.141 1.282 0.499
ENSG00000058335 E009 7.8003048 0.0017995980 4.477948e-01 7.461982e-01 15 78978380 78978890 511 - 0.864 0.775 -0.350
ENSG00000058335 E010 0.0000000       15 78978891 78978927 37 -      
ENSG00000058335 E011 0.0000000       15 78978928 78979202 275 -      
ENSG00000058335 E012 0.0000000       15 78979203 78979206 4 -      
ENSG00000058335 E013 8.0366470 0.0035193414 1.598858e-01 4.626531e-01 15 78980146 78980424 279 - 0.824 0.992 0.637
ENSG00000058335 E014 9.0566018 0.0014882258 1.916170e-01 5.067087e-01 15 78980425 78980619 195 - 0.930 0.775 -0.601
ENSG00000058335 E015 7.9297751 0.0579530353 7.939876e-01 9.290559e-01 15 78980620 78980656 37 - 0.864 0.813 -0.198
ENSG00000058335 E016 5.7306891 0.0941011520 9.283716e-01 9.800494e-01 15 78980657 78980699 43 - 0.738 0.733 -0.020
ENSG00000058335 E017 126.3870338 0.0002731083 7.327345e-09 6.461453e-07 15 78980700 78984446 3747 - 2.026 1.837 -0.636
ENSG00000058335 E018 0.0000000       15 78985007 78985204 198 -      
ENSG00000058335 E019 0.0000000       15 78985205 78985310 106 -      
ENSG00000058335 E020 6.8634649 0.0901956391 2.764684e-01 6.045896e-01 15 78990189 78990273 85 - 0.763 0.940 0.685
ENSG00000058335 E021 6.1771722 0.0635867485 1.395115e-01 4.323968e-01 15 78991691 78991711 21 - 0.711 0.940 0.897
ENSG00000058335 E022 9.3426249 0.0097224258 1.185581e-01 3.984386e-01 15 78991712 78991794 83 - 0.877 1.059 0.679
ENSG00000058335 E023 8.2101324 0.0061279965 7.060258e-01 8.901110e-01 15 78995740 78995800 61 - 0.858 0.911 0.205
ENSG00000058335 E024 0.2279811 0.0154142494 1.000000e+00   15 78997951 78998095 145 - 0.086 0.000 -10.993
ENSG00000058335 E025 12.4311694 0.0018045111 1.792313e-01 4.915619e-01 15 78998096 78998208 113 - 1.051 0.911 -0.517
ENSG00000058335 E026 0.1138060 0.0112115861 8.138195e-01   15 78998209 78998266 58 - 0.045 0.000 -10.087
ENSG00000058335 E027 13.0220479 0.0119946723 2.417793e-01 5.677901e-01 15 78998719 78998825 107 - 1.067 0.940 -0.470
ENSG00000058335 E028 10.9142089 0.0013039794 1.648398e-01 4.701383e-01 15 78999743 78999811 69 - 1.002 0.848 -0.578
ENSG00000058335 E029 13.3654188 0.0033176990 1.705525e-01 4.784373e-01 15 78999812 78999913 102 - 1.079 0.940 -0.513
ENSG00000058335 E030 24.5205546 0.0005734895 5.313999e-01 7.996500e-01 15 79001662 79001787 126 - 1.309 1.270 -0.138
ENSG00000058335 E031 48.5643731 0.0003154248 9.711652e-01 9.945268e-01 15 79003802 79004175 374 - 1.586 1.597 0.036
ENSG00000058335 E032 1.1754432 0.0105839661 7.924804e-01 9.285586e-01 15 79004450 79004527 78 - 0.272 0.322 0.338
ENSG00000058335 E033 0.1138060 0.0112115861 8.138195e-01   15 79004528 79004553 26 - 0.045 0.000 -10.087
ENSG00000058335 E034 0.8514086 0.0620552698 1.181693e-01 3.978069e-01 15 79004717 79005665 949 - 0.157 0.423 1.922
ENSG00000058335 E035 0.0000000       15 79006177 79006185 9 -      
ENSG00000058335 E036 0.8499045 0.1890618260 1.805622e-01 4.931483e-01 15 79006186 79006351 166 - 0.157 0.423 1.922
ENSG00000058335 E037 0.3587636 0.1946875035 4.264155e-01   15 79006352 79006434 83 - 0.086 0.190 1.338
ENSG00000058335 E038 0.7995217 0.0132890873 2.952927e-01 6.234404e-01 15 79012489 79012527 39 - 0.246 0.000 -12.553
ENSG00000058335 E039 0.2285450 0.0154403551 1.000000e+00   15 79015327 79015409 83 - 0.086 0.000 -10.993
ENSG00000058335 E040 0.4917146 0.0979100023 1.338405e-01   15 79017770 79017906 137 - 0.086 0.322 2.337
ENSG00000058335 E041 0.3604317 0.0165879671 4.161573e-01   15 79020041 79020104 64 - 0.086 0.190 1.338
ENSG00000058335 E042 0.2283502 0.2142796455 1.000000e+00   15 79025314 79025474 161 - 0.086 0.000 -10.505
ENSG00000058335 E043 0.3419313 0.0157377708 1.000000e+00   15 79027741 79027859 119 - 0.123 0.000 -11.515
ENSG00000058335 E044 0.2277562 0.0154262630 1.000000e+00   15 79031400 79031509 110 - 0.086 0.000 -10.993
ENSG00000058335 E045 0.1145948 0.0112505361 8.138016e-01   15 79032123 79032316 194 - 0.045 0.000 -10.087
ENSG00000058335 E046 0.0000000       15 79035131 79035210 80 -      
ENSG00000058335 E047 0.1139502 0.0112031543 8.136844e-01   15 79046746 79046999 254 - 0.045 0.000 -10.087
ENSG00000058335 E048 0.0000000       15 79049496 79049588 93 -      
ENSG00000058335 E049 0.2277562 0.0154262630 1.000000e+00   15 79058334 79058481 148 - 0.086 0.000 -10.993
ENSG00000058335 E050 0.3421562 0.0255169936 1.000000e+00   15 79064420 79064526 107 - 0.123 0.000 -11.475
ENSG00000058335 E051 0.2283502 0.2142796455 1.000000e+00   15 79064527 79064663 137 - 0.086 0.000 -10.505
ENSG00000058335 E052 0.2276119 0.2736808595 1.000000e+00   15 79090223 79090780 558 - 0.086 0.000 -10.431

Help

Please Click HERE to learn more details about the results from DEXseq.