ENSG00000064687

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000263094 ENSG00000064687 No_inf pgwt_inf ABCA7 protein_coding protein_coding 16.68391 29.59541 12.80302 2.658568 1.252771 -1.20825 3.1669339 4.9320079 2.57772044 0.9171935 0.30855029 -0.9334156 0.21955833 0.175825 0.208650 0.032825 0.993384045 0.002122501 FALSE TRUE
ENST00000433129 ENSG00000064687 No_inf pgwt_inf ABCA7 protein_coding retained_intron 16.68391 29.59541 12.80302 2.658568 1.252771 -1.20825 0.8358642 1.3874214 0.37582211 0.7383653 0.37582211 -1.8567594 0.05578333 0.046550 0.032450 -0.014100 0.992847247 0.002122501 TRUE TRUE
ENST00000524383 ENSG00000064687 No_inf pgwt_inf ABCA7 protein_coding protein_coding_CDS_not_defined 16.68391 29.59541 12.80302 2.658568 1.252771 -1.20825 0.4458342 0.0000000 0.77354123 0.0000000 0.77354123 6.2919373 0.04904167 0.000000 0.058925 0.058925 0.992847247 0.002122501   TRUE
ENST00000525073 ENSG00000064687 No_inf pgwt_inf ABCA7 protein_coding protein_coding 16.68391 29.59541 12.80302 2.658568 1.252771 -1.20825 1.5956704 4.5356027 0.00000000 0.7055788 0.00000000 -8.8283278 0.06345833 0.151500 0.000000 -0.151500 0.002122501 0.002122501 FALSE TRUE
ENST00000525238 ENSG00000064687 No_inf pgwt_inf ABCA7 protein_coding retained_intron 16.68391 29.59541 12.80302 2.658568 1.252771 -1.20825 0.8516853 2.2156294 0.09520321 0.5768275 0.09520321 -4.4029627 0.03733333 0.072300 0.005900 -0.066400 0.314750543 0.002122501   FALSE
ENST00000529442 ENSG00000064687 No_inf pgwt_inf ABCA7 protein_coding nonsense_mediated_decay 16.68391 29.59541 12.80302 2.658568 1.252771 -1.20825 0.4222636 0.0000000 1.26679073 0.0000000 1.26679073 6.9963783 0.02614167 0.000000 0.078425 0.078425 0.992847247 0.002122501 FALSE FALSE
ENST00000530092 ENSG00000064687 No_inf pgwt_inf ABCA7 protein_coding nonsense_mediated_decay 16.68391 29.59541 12.80302 2.658568 1.252771 -1.20825 0.6270505 0.8162735 1.06487802 0.8162735 0.61886988 0.3794816 0.03576667 0.027325 0.079975 0.052650 0.992847247 0.002122501   FALSE
ENST00000531478 ENSG00000064687 No_inf pgwt_inf ABCA7 protein_coding retained_intron 16.68391 29.59541 12.80302 2.658568 1.252771 -1.20825 0.2772110 0.0000000 0.83163295 0.0000000 0.60982174 6.3951193 0.01867500 0.000000 0.056025 0.056025 0.801346492 0.002122501 FALSE TRUE
ENST00000532194 ENSG00000064687 No_inf pgwt_inf ABCA7 protein_coding retained_intron 16.68391 29.59541 12.80302 2.658568 1.252771 -1.20825 1.6682879 2.8509220 0.71767989 1.0551865 0.71767989 -1.9751043 0.11135833 0.091700 0.069350 -0.022350 0.982254070 0.002122501 FALSE FALSE
MSTRG.14172.10 ENSG00000064687 No_inf pgwt_inf ABCA7 protein_coding   16.68391 29.59541 12.80302 2.658568 1.252771 -1.20825 0.9694226 2.6204358 0.09076460 0.8813922 0.09076460 -4.7062411 0.03968333 0.082600 0.005625 -0.076975 0.766642781 0.002122501 FALSE TRUE
MSTRG.14172.16 ENSG00000064687 No_inf pgwt_inf ABCA7 protein_coding   16.68391 29.59541 12.80302 2.658568 1.252771 -1.20825 2.0132264 4.2014995 0.56025560 1.5392040 0.56025560 -2.8846534 0.11329167 0.141050 0.042675 -0.098375 0.944357681 0.002122501 FALSE TRUE
MSTRG.14172.2 ENSG00000064687 No_inf pgwt_inf ABCA7 protein_coding   16.68391 29.59541 12.80302 2.658568 1.252771 -1.20825 0.3807027 0.2698064 0.87230178 0.1600681 0.76893341 1.6568431 0.02531667 0.010650 0.065300 0.054650 0.992847247 0.002122501 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000064687 E001 0.1308632 0.0121934087 1.0000000000   19 1039997 1040102 106 + 0.000 0.058 8.108
ENSG00000064687 E002 0.1308632 0.0121934087 1.0000000000   19 1040103 1040106 4 + 0.000 0.058 10.556
ENSG00000064687 E003 0.1308632 0.0121934087 1.0000000000   19 1040107 1040113 7 + 0.000 0.058 10.556
ENSG00000064687 E004 0.2454580 0.0162210173 0.4010315899   19 1040114 1040115 2 + 0.152 0.058 -1.542
ENSG00000064687 E005 0.2454580 0.0162210173 0.4010315899   19 1040116 1040117 2 + 0.152 0.058 -1.542
ENSG00000064687 E006 0.2454580 0.0162210173 0.4010315899   19 1040118 1040119 2 + 0.152 0.058 -1.542
ENSG00000064687 E007 0.4901271 0.0653737684 0.2998929574   19 1040120 1040136 17 + 0.264 0.110 -1.542
ENSG00000064687 E008 0.7534508 0.0283609756 0.6737636594 0.87380442 19 1040137 1040138 2 + 0.264 0.197 -0.542
ENSG00000064687 E009 2.2946074 0.0069421501 0.7452826150 0.90866248 19 1040139 1040196 58 + 0.427 0.478 0.266
ENSG00000064687 E010 0.0000000       19 1041202 1041204 3 +      
ENSG00000064687 E011 0.0000000       19 1041205 1041224 20 +      
ENSG00000064687 E012 2.4425376 0.0085772545 0.3108372934 0.63713304 19 1041225 1041263 39 + 0.353 0.518 0.873
ENSG00000064687 E013 4.2250995 0.0038006293 0.0496159505 0.24645947 19 1041264 1041354 91 + 0.836 0.588 -1.027
ENSG00000064687 E014 5.5832257 0.0030294825 0.0161255681 0.12607392 19 1041355 1041427 73 + 0.951 0.675 -1.089
ENSG00000064687 E015 0.1139502 0.0110435111 0.1577400469   19 1041428 1041509 82 + 0.152 0.000 -13.861
ENSG00000064687 E016 2.9168658 0.0147182177 0.9535635875 0.98863381 19 1041510 1041515 6 + 0.545 0.536 -0.039
ENSG00000064687 E017 7.7622364 0.0023233605 0.0856423893 0.33507713 19 1041516 1041603 88 + 1.008 0.829 -0.679
ENSG00000064687 E018 2.6891335 0.0363754569 0.5188137910 0.79190371 19 1041604 1041830 227 + 0.427 0.536 0.546
ENSG00000064687 E019 10.0885006 0.0030419672 0.3744683422 0.69207027 19 1041831 1041972 142 + 1.042 0.956 -0.319
ENSG00000064687 E020 2.1955284 0.0494469677 0.1916720213 0.50680385 19 1041973 1042063 91 + 0.264 0.499 1.365
ENSG00000064687 E021 7.6581657 0.0464340261 0.2693942109 0.59744584 19 1042064 1042176 113 + 0.971 0.838 -0.506
ENSG00000064687 E022 2.6514475 0.0682169716 0.7582286968 0.91411733 19 1042315 1042319 5 + 0.545 0.499 -0.220
ENSG00000064687 E023 4.6294091 0.1504975670 0.3514031286 0.67165646 19 1042320 1042397 78 + 0.808 0.648 -0.657
ENSG00000064687 E024 5.4167598 0.1065229919 0.5246504310 0.79541890 19 1042398 1042591 194 + 0.808 0.724 -0.336
ENSG00000064687 E025 6.5203039 0.0256081715 0.3720376884 0.69021005 19 1042592 1042745 154 + 0.714 0.838 0.494
ENSG00000064687 E026 5.6850454 0.0025693428 0.6161917610 0.84570484 19 1042746 1042826 81 + 0.808 0.748 -0.242
ENSG00000064687 E027 7.7203777 0.0285451764 0.7148719965 0.89415995 19 1043041 1043251 211 + 0.909 0.864 -0.170
ENSG00000064687 E028 7.5102536 0.0028817537 0.7453160994 0.90866312 19 1043334 1043473 140 + 0.836 0.873 0.143
ENSG00000064687 E029 6.7697132 0.0021510348 0.4145490034 0.72195812 19 1043725 1043841 117 + 0.748 0.847 0.391
ENSG00000064687 E030 9.3638501 0.0017969426 0.0253825832 0.16730318 19 1044577 1044744 168 + 1.104 0.889 -0.794
ENSG00000064687 E031 12.2731249 0.0011574483 0.6113391094 0.84327910 19 1045002 1045231 230 + 1.089 1.043 -0.167
ENSG00000064687 E032 0.2450991 0.0160772870 0.4017847041   19 1045532 1045619 88 + 0.152 0.058 -1.542
ENSG00000064687 E033 11.4064987 0.0078010341 0.8283483616 0.94218592 19 1046230 1046404 175 + 1.042 1.020 -0.082
ENSG00000064687 E034 2.1622791 0.0511428257 0.8750581507 0.96049411 19 1046405 1046406 2 + 0.427 0.457 0.159
ENSG00000064687 E035 11.3333034 0.0013005889 0.2389709058 0.56475135 19 1046802 1047024 223 + 1.104 0.995 -0.395
ENSG00000064687 E036 12.5189300 0.0010983863 0.5401767834 0.80520666 19 1047157 1047378 222 + 1.104 1.049 -0.199
ENSG00000064687 E037 12.3522759 0.0016605516 0.2627696985 0.59077555 19 1047453 1047654 202 + 1.131 1.032 -0.361
ENSG00000064687 E038 9.3095061 0.0142155779 0.2242232516 0.54843760 19 1048895 1049005 111 + 1.042 0.912 -0.483
ENSG00000064687 E039 10.4876201 0.0013422487 0.4914671808 0.77506246 19 1049266 1049414 149 + 1.042 0.976 -0.244
ENSG00000064687 E040 3.6524409 0.0040045583 0.5130592107 0.78856543 19 1049415 1049437 23 + 0.678 0.588 -0.390
ENSG00000064687 E041 6.7185240 0.0023287597 0.8902000292 0.96616697 19 1050921 1051052 132 + 0.836 0.819 -0.063
ENSG00000064687 E042 8.0942581 0.0018512394 0.6448704120 0.85969241 19 1051155 1051294 140 + 0.930 0.881 -0.188
ENSG00000064687 E043 9.8516500 0.0014275754 0.2078981715 0.52849123 19 1051449 1051586 138 + 0.861 0.995 0.506
ENSG00000064687 E044 11.5878190 0.0298559198 0.6848407177 0.87977888 19 1051942 1052126 185 + 0.990 1.043 0.196
ENSG00000064687 E045 6.1922644 0.0248292582 0.6556787091 0.86577609 19 1052214 1052286 73 + 0.836 0.780 -0.220
ENSG00000064687 E046 12.0745329 0.0012887569 0.1408734585 0.43441234 19 1053329 1053531 203 + 1.145 1.014 -0.473
ENSG00000064687 E047 5.6201550 0.0071806048 0.0810008823 0.32531494 19 1053788 1053836 49 + 0.909 0.701 -0.822
ENSG00000064687 E048 5.8998635 0.0027697793 0.2003153883 0.51867831 19 1054006 1054075 70 + 0.886 0.736 -0.587
ENSG00000064687 E049 3.1456619 0.0046956159 0.4756007482 0.76511320 19 1054076 1054110 35 + 0.638 0.536 -0.454
ENSG00000064687 E050 8.9350246 0.0016013599 0.4198903163 0.72602102 19 1054193 1054341 149 + 0.861 0.949 0.333
ENSG00000064687 E051 3.7698765 0.0051893515 0.3494960871 0.67012620 19 1054570 1054599 30 + 0.714 0.588 -0.542
ENSG00000064687 E052 5.2471453 0.0027524755 0.3637154526 0.68308626 19 1054600 1054694 95 + 0.638 0.759 0.503
ENSG00000064687 E053 9.0221377 0.0138803388 0.1087547017 0.38067731 19 1054780 1054878 99 + 1.059 0.889 -0.631
ENSG00000064687 E054 0.6555391 0.0148123820 0.2278883899 0.55299864 19 1055083 1055096 14 + 0.000 0.235 12.707
ENSG00000064687 E055 16.2672753 0.0156663318 0.3018280243 0.62888934 19 1055097 1055351 255 + 1.238 1.143 -0.335
ENSG00000064687 E056 5.3460381 0.0199301979 0.8112736228 0.93567549 19 1055907 1055939 33 + 0.714 0.748 0.137
ENSG00000064687 E057 1.3928010 0.0989413242 0.8711835883 0.95943514 19 1055985 1056065 81 + 0.353 0.332 -0.126
ENSG00000064687 E058 16.2111517 0.0008671519 0.2547225229 0.58167505 19 1056066 1056243 178 + 1.089 1.186 0.347
ENSG00000064687 E059 11.7859358 0.0011921406 0.1072870175 0.37843446 19 1056330 1056417 88 + 0.909 1.070 0.600
ENSG00000064687 E060 12.9590349 0.0048063060 0.8048077676 0.93328728 19 1056418 1056499 82 + 1.059 1.081 0.081
ENSG00000064687 E061 5.5670717 0.0502517362 0.8906678493 0.96645736 19 1056907 1056927 21 + 0.779 0.747 -0.127
ENSG00000064687 E062 4.9615439 0.1072385523 0.6780718662 0.87601032 19 1056928 1056933 6 + 0.677 0.725 0.195
ENSG00000064687 E063 14.6730840 0.0040896315 0.6272569725 0.85075188 19 1056934 1057084 151 + 1.157 1.116 -0.149
ENSG00000064687 E064 1.2797866 0.0486199119 0.6948210857 0.88403011 19 1057085 1057313 229 + 0.264 0.332 0.458
ENSG00000064687 E065 14.5177387 0.0086610848 0.5414452776 0.80580779 19 1057314 1057429 116 + 1.074 1.134 0.217
ENSG00000064687 E066 1.5061229 0.0640094100 0.5666276196 0.81932813 19 1057430 1057914 485 + 0.427 0.332 -0.541
ENSG00000064687 E067 10.1237068 0.0015198600 0.6946231426 0.88400835 19 1057915 1057968 54 + 1.008 0.970 -0.143
ENSG00000064687 E068 7.6185880 0.0018413443 0.9214359004 0.97766167 19 1057969 1057999 31 + 0.861 0.873 0.043
ENSG00000064687 E069 9.0288193 0.0026953331 0.7576913389 0.91395957 19 1058000 1058059 60 + 0.909 0.942 0.126
ENSG00000064687 E070 0.2623781 0.0160371338 1.0000000000   19 1058060 1058145 86 + 0.000 0.110 11.500
ENSG00000064687 E071 14.7687975 0.0017790675 0.5726370818 0.82325509 19 1058146 1058269 124 + 1.089 1.139 0.179
ENSG00000064687 E072 1.2953228 0.0101334890 0.2248124306 0.54912573 19 1058270 1058617 348 + 0.152 0.360 1.628
ENSG00000064687 E073 20.5725411 0.0008752377 0.1296971813 0.41790544 19 1058618 1058747 130 + 1.170 1.287 0.414
ENSG00000064687 E074 9.9135101 0.0052362375 0.8163121156 0.93729171 19 1058820 1058878 59 + 0.951 0.976 0.093
ENSG00000064687 E075 12.4010401 0.0012838080 0.6550855938 0.86552363 19 1058879 1058940 62 + 1.089 1.049 -0.147
ENSG00000064687 E076 13.0293390 0.0013401213 0.2384343683 0.56408605 19 1059023 1059080 58 + 0.990 1.101 0.406
ENSG00000064687 E077 7.1616247 0.0023164454 0.2975657406 0.62523550 19 1059081 1059085 5 + 0.748 0.873 0.491
ENSG00000064687 E078 0.7873398 0.0201011185 0.1554939286 0.45655092 19 1059086 1059282 197 + 0.000 0.270 12.939
ENSG00000064687 E079 16.1616083 0.0067923803 0.0379889939 0.21210388 19 1061782 1061888 107 + 1.008 1.202 0.699
ENSG00000064687 E080 2.0478530 0.0080030158 0.5226820746 0.79432467 19 1061968 1062171 204 + 0.353 0.457 0.574
ENSG00000064687 E081 5.9697718 0.0023188840 0.0036385215 0.04653205 19 1062172 1062178 7 + 0.427 0.847 1.851
ENSG00000064687 E082 13.3195011 0.0010890639 0.0004442146 0.00961969 19 1062179 1062313 135 + 0.779 1.148 1.381
ENSG00000064687 E083 12.8868856 0.0012009839 0.3759010071 0.69342592 19 1063544 1063678 135 + 1.008 1.091 0.303
ENSG00000064687 E084 9.2899735 0.0119504022 0.6881790290 0.88101426 19 1063760 1063863 104 + 0.909 0.956 0.178
ENSG00000064687 E085 1.0160610 0.0123472142 0.9720654698 0.99487209 19 1063864 1063899 36 + 0.264 0.270 0.043
ENSG00000064687 E086 1.1658613 0.1239091355 0.3428519565 0.66428114 19 1063900 1064051 152 + 0.152 0.332 1.459
ENSG00000064687 E087 1.2608720 0.0105317613 0.7525037365 0.91138484 19 1064052 1064160 109 + 0.353 0.302 -0.319
ENSG00000064687 E088 7.7981420 0.0211922510 0.3317030958 0.65536604 19 1064161 1064253 93 + 0.779 0.905 0.488
ENSG00000064687 E089 0.0000000       19 1064659 1064747 89 +      
ENSG00000064687 E090 5.8686866 0.0337066324 0.5792535425 0.82606457 19 1064931 1064975 45 + 0.714 0.790 0.307
ENSG00000064687 E091 17.1185244 0.0008756155 0.9237439617 0.97835744 19 1064976 1065171 196 + 1.194 1.186 -0.027
ENSG00000064687 E092 6.1083305 0.0229081575 0.7114187295 0.89274872 19 1065270 1065290 21 + 0.748 0.800 0.208
ENSG00000064687 E093 17.4001109 0.0008132563 0.8409613813 0.94743794 19 1065291 1065572 282 + 1.182 1.198 0.057

Help

Please Click HERE to learn more details about the results from DEXseq.