ENSG00000066117

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000381513 ENSG00000066117 No_inf pgwt_inf SMARCD1 protein_coding protein_coding 12.83395 15.39 11.243 0.4757359 0.501324 -0.4526208 2.0404130 1.386013 2.2984198 0.5283017 0.7919391 0.7255935 0.16537500 0.088975 0.20335 0.114375 9.928472e-01 6.269836e-06 FALSE TRUE
ENST00000394963 ENSG00000066117 No_inf pgwt_inf SMARCD1 protein_coding protein_coding 12.83395 15.39 11.243 0.4757359 0.501324 -0.4526208 4.2469195 4.225001 3.8836384 0.6643215 1.4064368 -0.1212434 0.33663333 0.277550 0.34250 0.064950 1.000000e+00 6.269836e-06 FALSE TRUE
ENST00000548573 ENSG00000066117 No_inf pgwt_inf SMARCD1 protein_coding protein_coding 12.83395 15.39 11.243 0.4757359 0.501324 -0.4526208 1.6578796 0.000000 4.1387654 0.0000000 0.2911295 8.6965383 0.14815833 0.000000 0.37115 0.371150 6.269836e-06 6.269836e-06 FALSE TRUE
ENST00000549526 ENSG00000066117 No_inf pgwt_inf SMARCD1 protein_coding protein_coding_CDS_not_defined 12.83395 15.39 11.243 0.4757359 0.501324 -0.4526208 0.9306019 2.791806 0.0000000 1.1171643 0.0000000 -8.1302131 0.05869167 0.176075 0.00000 -0.176075 3.251302e-01 6.269836e-06   FALSE
MSTRG.6461.8 ENSG00000066117 No_inf pgwt_inf SMARCD1 protein_coding   12.83395 15.39 11.243 0.4757359 0.501324 -0.4526208 3.4450532 6.159959 0.3174504 0.6599511 0.3174504 -4.2359125 0.25191667 0.401750 0.03000 -0.371750 6.014425e-02 6.269836e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000066117 E001 0.1138060 0.0113335930 0.441008582   12 50085200 50085324 125 + 0.103 0.000 -11.006
ENSG00000066117 E002 0.2446691 0.0164287772 0.877868033   12 50085325 50085327 3 + 0.103 0.088 -0.250
ENSG00000066117 E003 0.8669661 0.0130106847 0.905352502 0.97223658 12 50085328 50085341 14 + 0.255 0.278 0.165
ENSG00000066117 E004 0.9809163 0.0118448067 0.783221787 0.92486235 12 50085342 50085352 11 + 0.316 0.278 -0.250
ENSG00000066117 E005 6.0561316 0.0024842050 0.974649309 0.99556582 12 50085353 50085546 194 + 0.837 0.849 0.046
ENSG00000066117 E006 0.0000000       12 50085683 50085870 188 +      
ENSG00000066117 E007 4.7928716 0.0033185505 0.653027511 0.86438786 12 50086161 50086266 106 + 0.783 0.740 -0.176
ENSG00000066117 E008 4.8748646 0.0030071717 0.212847639 0.53487067 12 50086267 50086348 82 + 0.837 0.703 -0.539
ENSG00000066117 E009 4.8477261 0.0246380927 0.616076929 0.84567470 12 50086621 50086663 43 + 0.722 0.790 0.274
ENSG00000066117 E010 8.3689088 0.0018322241 0.195896747 0.51264297 12 50086756 50086878 123 + 0.885 1.018 0.499
ENSG00000066117 E011 0.2633236 0.2459685400 0.376582414   12 50086879 50086917 39 + 0.000 0.161 11.306
ENSG00000066117 E012 3.3052881 0.0044690173 0.486778395 0.77240926 12 50087363 50087415 53 + 0.676 0.593 -0.357
ENSG00000066117 E013 6.2062080 0.0067516879 0.666528188 0.87060960 12 50087416 50087485 70 + 0.820 0.876 0.216
ENSG00000066117 E014 0.0000000       12 50088235 50088290 56 +      
ENSG00000066117 E015 4.8790227 0.0031162567 0.246309460 0.57293769 12 50088521 50088524 4 + 0.676 0.820 0.587
ENSG00000066117 E016 10.2817225 0.0013734909 0.748238401 0.90969640 12 50088525 50088637 113 + 1.026 1.063 0.135
ENSG00000066117 E017 1.9456246 0.1785959834 0.481926733 0.76913977 12 50088638 50089422 785 + 0.532 0.410 -0.612
ENSG00000066117 E018 9.5277181 0.0014762737 0.866102741 0.95733504 12 50089884 50089985 102 + 1.003 1.028 0.089
ENSG00000066117 E019 15.9244352 0.0009189349 0.885715019 0.96433284 12 50090241 50090402 162 + 1.224 1.223 -0.003
ENSG00000066117 E020 12.5019368 0.0142976465 0.312439800 0.63828145 12 50090493 50090590 98 + 1.173 1.087 -0.306
ENSG00000066117 E021 8.2650773 0.0042076835 0.846560293 0.94934801 12 50094437 50094505 69 + 0.967 0.958 -0.034
ENSG00000066117 E022 7.6119973 0.0821681586 0.390983083 0.70470675 12 50094506 50094572 67 + 0.854 0.979 0.476
ENSG00000066117 E023 0.2625250 0.0160668178 0.317750271   12 50096659 50096849 191 + 0.000 0.161 11.306
ENSG00000066117 E024 8.9611776 0.0020695486 0.007487368 0.07677698 12 50096850 50096972 123 + 0.820 1.087 1.002
ENSG00000066117 E025 0.3600626 0.0168104864 0.468700520   12 50098495 50098713 219 + 0.186 0.088 -1.250
ENSG00000066117 E026 10.9259974 0.0238406344 0.480173423 0.76778245 12 50098714 50098815 102 + 1.105 1.045 -0.217
ENSG00000066117 E027 18.9834936 0.0008608096 0.674879198 0.87446027 12 50098947 50099141 195 + 1.306 1.288 -0.062
ENSG00000066117 E028 23.5776526 0.0010085390 0.214895950 0.53718359 12 50099142 50099429 288 + 1.421 1.358 -0.220
ENSG00000066117 E029 8.7853363 0.0756671542 0.779267378 0.92355056 12 50099430 50099486 57 + 0.967 0.999 0.118
ENSG00000066117 E030 11.7460214 0.0086988436 0.213943654 0.53610634 12 50099487 50099565 79 + 1.157 1.054 -0.370
ENSG00000066117 E031 17.9239190 0.0024768393 0.240361063 0.56627202 12 50099566 50099799 234 + 1.311 1.240 -0.250
ENSG00000066117 E032 23.8430588 0.0006791887 0.266436262 0.59458699 12 50099800 50100053 254 + 1.421 1.366 -0.190
ENSG00000066117 E033 44.6093189 0.0239891430 0.114717305 0.39148128 12 50100054 50100707 654 + 1.584 1.699 0.389

Help

Please Click HERE to learn more details about the results from DEXseq.