ENSG00000067596

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262415 ENSG00000067596 No_inf pgwt_inf DHX8 protein_coding protein_coding 25.4886 20.95515 27.75422 1.524991 2.163698 0.4052335 10.531670 9.979637 10.255357 0.211359 0.3911574 0.03927963 0.4234167 0.483425 0.37735 -0.106075 9.928472e-01 1.770412e-05 FALSE TRUE
ENST00000540306 ENSG00000067596 No_inf pgwt_inf DHX8 protein_coding protein_coding 25.4886 20.95515 27.75422 1.524991 2.163698 0.4052335 3.917098 0.000000 6.628010 0.000000 0.4339426 9.37460701 0.1422667 0.000000 0.24290 0.242900 1.770412e-05 1.770412e-05 FALSE TRUE
ENST00000587574 ENSG00000067596 No_inf pgwt_inf DHX8 protein_coding protein_coding 25.4886 20.95515 27.75422 1.524991 2.163698 0.4052335 9.249464 9.900029 9.555318 1.507368 1.7666579 -0.05107635 0.3660167 0.463975 0.33545 -0.128525 9.928472e-01 1.770412e-05   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000067596 E001 0.0000000       17 43483865 43483959 95 +      
ENSG00000067596 E002 0.0000000       17 43483960 43483962 3 +      
ENSG00000067596 E003 0.2279004 0.2393305797 0.4292079246   17 43483963 43483974 12 + 0.152 0.000 -9.211
ENSG00000067596 E004 7.0233236 0.0019602711 0.0362046236 0.2065733714 17 43483975 43484139 165 + 0.992 0.767 -0.862
ENSG00000067596 E005 7.1690772 0.0469832034 0.2026255216 0.5217081404 17 43484140 43484185 46 + 0.983 0.808 -0.667
ENSG00000067596 E006 9.6097549 0.0014855611 0.1967677783 0.5136897081 17 43489449 43489534 86 + 1.076 0.954 -0.450
ENSG00000067596 E007 9.2336931 0.0016340921 0.1372443530 0.4290591873 17 43490391 43490463 73 + 1.069 0.925 -0.529
ENSG00000067596 E008 0.0000000       17 43490464 43490493 30 +      
ENSG00000067596 E009 6.1724059 0.0023129648 0.0242494681 0.1622601473 17 43491165 43491193 29 + 0.953 0.699 -0.998
ENSG00000067596 E010 7.6093804 0.0075926965 0.0274165303 0.1749379642 17 43491194 43491250 57 + 1.028 0.788 -0.911
ENSG00000067596 E011 9.8515171 0.0013586990 0.0032707761 0.0431912984 17 43492183 43492292 110 + 1.140 0.862 -1.028
ENSG00000067596 E012 22.2239155 0.0233479846 0.1396570915 0.4325711160 17 43492681 43493040 360 + 1.422 1.285 -0.476
ENSG00000067596 E013 11.2611319 0.0013418673 0.0713921787 0.3033183251 17 43493445 43493589 145 + 1.153 0.993 -0.580
ENSG00000067596 E014 18.7116978 0.0313462658 0.1848109719 0.4983175159 17 43493683 43493886 204 + 1.355 1.208 -0.515
ENSG00000067596 E015 10.4931737 0.0431679717 0.0872689676 0.3386768341 17 43496181 43496268 88 + 1.147 0.925 -0.811
ENSG00000067596 E016 11.6936961 0.0047680184 0.3381751658 0.6606936129 17 43498862 43498959 98 + 1.140 1.052 -0.318
ENSG00000067596 E017 14.7956419 0.0060295077 0.9527384267 0.9884898589 17 43499956 43500103 148 + 1.202 1.192 -0.034
ENSG00000067596 E018 16.4884695 0.0008550471 0.2833354782 0.6110313290 17 43504644 43504825 182 + 1.207 1.278 0.250
ENSG00000067596 E019 18.8101773 0.0007787454 0.2768270958 0.6049083399 17 43507003 43507197 195 + 1.330 1.251 -0.274
ENSG00000067596 E020 19.5170282 0.0040624947 0.9060949114 0.9722384745 17 43507503 43507688 186 + 1.317 1.304 -0.046
ENSG00000067596 E021 22.1068302 0.0008228378 0.3637903357 0.6831419413 17 43507809 43508019 211 + 1.390 1.328 -0.215
ENSG00000067596 E022 20.6004049 0.0056348239 0.8195787887 0.9384039250 17 43508339 43508520 182 + 1.342 1.322 -0.072
ENSG00000067596 E023 19.8921233 0.0037160819 0.9956747798 1.0000000000 17 43513362 43513502 141 + 1.321 1.316 -0.018
ENSG00000067596 E024 24.9161124 0.0133944489 0.5855148602 0.8299770859 17 43517167 43517322 156 + 1.432 1.387 -0.154
ENSG00000067596 E025 1.6389997 0.1499218956 0.1023554889 0.3685722203 17 43517323 43520129 2807 + 0.265 0.553 1.614
ENSG00000067596 E026 22.2419507 0.0078698208 0.7851272146 0.9255148547 17 43520130 43520267 138 + 1.359 1.372 0.046
ENSG00000067596 E027 20.1534613 0.0007016578 0.2334131446 0.5587881353 17 43520751 43520879 129 + 1.290 1.361 0.250
ENSG00000067596 E028 34.6157486 0.0004404463 0.3019297846 0.6289797675 17 43521369 43521565 197 + 1.528 1.574 0.157
ENSG00000067596 E029 27.0215704 0.0116562002 0.6034507264 0.8390901897 17 43522047 43522151 105 + 1.432 1.462 0.104
ENSG00000067596 E030 19.3151154 0.0143953705 0.8762626668 0.9608561766 17 43522152 43522226 75 + 1.303 1.310 0.022
ENSG00000067596 E031 73.1887685 0.0002157201 0.0016221516 0.0259378134 17 43523628 43524185 558 + 1.820 1.920 0.337
ENSG00000067596 E032 81.6891044 0.0002009653 0.0000267219 0.0009809948 17 43524186 43526386 2201 + 1.853 1.980 0.426
ENSG00000067596 E033 8.9974468 0.0249044592 0.0961324512 0.3569844600 17 43526387 43526495 109 + 0.911 1.084 0.641
ENSG00000067596 E034 13.0772793 0.0010550942 0.7765955619 0.9223759196 17 43526496 43526803 308 + 1.160 1.132 -0.098
ENSG00000067596 E035 0.1145948 0.0112130614 0.7409334831   17 43536412 43536498 87 + 0.083 0.000 -11.545
ENSG00000067596 E036 0.8683313 0.0152929184 0.4298531770 0.7332444351 17 43544162 43544784 623 + 0.212 0.331 0.858
ENSG00000067596 E037 0.0000000       17 43544785 43544815 31 +      
ENSG00000067596 E038 0.0000000       17 43590088 43590165 78 +      
ENSG00000067596 E039 0.0000000       17 43590166 43590741 576 +      
ENSG00000067596 E040 0.0000000       17 43609887 43610338 452 +      

Help

Please Click HERE to learn more details about the results from DEXseq.