ENSG00000067992

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000379162 ENSG00000067992 No_inf pgwt_inf PDK3 protein_coding protein_coding 3.31765 2.494381 3.194505 0.1495565 0.009091803 0.3556473 1.1233653 0.0000000 1.30852533 0.00000000 0.13210843 7.0427815 0.29447500 0.000000 0.409425 0.409425 0.0155661 0.0155661 FALSE TRUE
ENST00000493226 ENSG00000067992 No_inf pgwt_inf PDK3 protein_coding retained_intron 3.31765 2.494381 3.194505 0.1495565 0.009091803 0.3556473 0.1128685 0.1807252 0.03213809 0.07431260 0.03213809 -2.1782989 0.03466667 0.069075 0.010000 -0.059075 0.9763898 0.0155661 FALSE FALSE
ENST00000568479 ENSG00000067992 No_inf pgwt_inf PDK3 protein_coding protein_coding 3.31765 2.494381 3.194505 0.1495565 0.009091803 0.3556473 1.8482947 2.0171647 1.53501414 0.10814193 0.11616526 -0.3918432 0.59121667 0.810400 0.480600 -0.329800 0.5159406 0.0155661 FALSE TRUE
ENST00000688551 ENSG00000067992 No_inf pgwt_inf PDK3 protein_coding retained_intron 3.31765 2.494381 3.194505 0.1495565 0.009091803 0.3556473 0.2122781 0.2964911 0.25629675 0.02433932 0.08078995 -0.2028102 0.07310833 0.120525 0.080350 -0.040175 0.9928472 0.0155661 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000067992 E001 0.2620121 0.016110360 2.833236e-01   X 24465244 24465269 26 + 0.000 0.164 9.715
ENSG00000067992 E002 0.3766069 0.016966637 6.562471e-01   X 24465270 24465285 16 + 0.101 0.164 0.813
ENSG00000067992 E003 2.2087539 0.006268955 8.126842e-01 0.9362650021 X 24465286 24465561 276 + 0.525 0.487 -0.186
ENSG00000067992 E004 2.6300134 0.005639008 4.848561e-02 0.2430507354 X 24494742 24494883 142 + 0.692 0.416 -1.286
ENSG00000067992 E005 2.3857257 0.008419529 4.147546e-02 0.2233028893 X 24498829 24498900 72 + 0.668 0.376 -1.409
ENSG00000067992 E006 0.5079848 0.023232766 3.781446e-01   X 24498901 24500155 1255 + 0.101 0.228 1.399
ENSG00000067992 E007 3.7260231 0.004427528 5.295935e-02 0.2567254232 X 24503327 24503511 185 + 0.794 0.547 -1.049
ENSG00000067992 E008 2.3205252 0.009354244 6.395265e-01 0.8571475917 X 24505209 24505298 90 + 0.558 0.487 -0.338
ENSG00000067992 E009 3.0065790 0.010395773 9.693602e-02 0.3585525067 X 24518933 24519010 78 + 0.714 0.486 -1.017
ENSG00000067992 E010 1.0149545 0.013875823 2.004633e-01 0.5189094265 X 24524183 24525396 1214 + 0.183 0.376 1.398
ENSG00000067992 E011 0.6048862 0.016032017 5.710818e-01   X 24525397 24526197 801 + 0.251 0.164 -0.771
ENSG00000067992 E012 3.6161081 0.128662369 2.395002e-01 0.5652220834 X 24526198 24526274 77 + 0.776 0.547 -0.975
ENSG00000067992 E013 4.1564435 0.003812173 5.044590e-01 0.7834448401 X 24527574 24527675 102 + 0.756 0.670 -0.356
ENSG00000067992 E014 4.8287386 0.003186752 6.485051e-01 0.8616856515 X 24528076 24528186 111 + 0.736 0.782 0.186
ENSG00000067992 E015 3.9888717 0.025542980 1.582215e-01 0.4604212286 X 24531657 24531770 114 + 0.794 0.600 -0.808
ENSG00000067992 E016 4.2168614 0.079020616 1.780111e-01 0.4900331582 X 24533929 24534068 140 + 0.829 0.600 -0.945
ENSG00000067992 E017 1.5526308 0.017275749 1.148076e-01 0.3916384022 X 24534069 24534656 588 + 0.525 0.283 -1.356
ENSG00000067992 E018 0.4563012 0.016370165 3.444883e-02   X 24534657 24535492 836 + 0.311 0.000 -13.712
ENSG00000067992 E019 107.4359867 0.000187530 2.416166e-06 0.0001229766 X 24539134 24550466 11333 + 1.992 2.059 0.226

Help

Please Click HERE to learn more details about the results from DEXseq.