ENSG00000070423

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000292363 ENSG00000070423 No_inf pgwt_inf RNF126 protein_coding protein_coding 36.95889 28.08854 46.23661 1.276225 0.9821772 0.7188527 24.347615 13.0118333 32.122524 4.5579763 0.9122390 1.3031017 0.64279167 0.466650 0.696250 0.229600 9.928472e-01 2.019835e-05 FALSE TRUE
ENST00000586749 ENSG00000070423 No_inf pgwt_inf RNF126 protein_coding retained_intron 36.95889 28.08854 46.23661 1.276225 0.9821772 0.7188527 2.784986 2.9043856 3.915249 0.2841086 0.4018638 0.4295923 0.07685833 0.103925 0.084725 -0.019200 9.928472e-01 2.019835e-05 TRUE TRUE
ENST00000589762 ENSG00000070423 No_inf pgwt_inf RNF126 protein_coding protein_coding 36.95889 28.08854 46.23661 1.276225 0.9821772 0.7188527 2.493724 0.5345407 4.067821 0.5345407 1.5179043 2.9046866 0.06092500 0.017925 0.088100 0.070175 8.942454e-01 2.019835e-05 FALSE TRUE
MSTRG.14147.5 ENSG00000070423 No_inf pgwt_inf RNF126 protein_coding   36.95889 28.08854 46.23661 1.276225 0.9821772 0.7188527 2.512824 5.1302113 0.000000 0.9110075 0.0000000 -9.0056838 0.08441667 0.186475 0.000000 -0.186475 2.019835e-05 2.019835e-05 TRUE TRUE
MSTRG.14147.6 ENSG00000070423 No_inf pgwt_inf RNF126 protein_coding   36.95889 28.08854 46.23661 1.276225 0.9821772 0.7188527 2.122164 4.1616414 2.204850 4.1616414 2.2048504 -0.9134059 0.06299167 0.142225 0.046750 -0.095475 1.000000e+00 2.019835e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000070423 E001 0.2617264 0.2336578248 0.158639635   19 647526 647528 3 - 0.000 0.209 11.125
ENSG00000070423 E002 0.2617264 0.2336578248 0.158639635   19 647529 647529 1 - 0.000 0.209 13.261
ENSG00000070423 E003 0.5074701 0.0245523689 0.146783666   19 647530 647540 11 - 0.077 0.285 2.260
ENSG00000070423 E004 0.9814803 0.0164101342 0.517443499 0.79117998 19 647541 647556 16 - 0.249 0.350 0.675
ENSG00000070423 E005 84.2558872 0.0032884202 0.349367313 0.67000817 19 647557 648131 575 - 1.911 1.944 0.113
ENSG00000070423 E006 45.0391524 0.0003377958 0.428426052 0.73228535 19 648132 648277 146 - 1.671 1.637 -0.115
ENSG00000070423 E007 36.8926121 0.0119900755 0.783657052 0.92496483 19 648372 648487 116 - 1.580 1.563 -0.057
ENSG00000070423 E008 30.8790006 0.0010633975 0.831749295 0.94350705 19 648882 648975 94 - 1.502 1.491 -0.038
ENSG00000070423 E009 4.9961496 0.0029154712 0.002411889 0.03477391 19 648976 649052 77 - 0.592 0.941 1.412
ENSG00000070423 E010 13.1616655 0.0037000556 0.160216424 0.46304910 19 649053 649678 626 - 1.094 1.208 0.407
ENSG00000070423 E011 23.3376169 0.0017338155 0.482206366 0.76920598 19 649679 649748 70 - 1.398 1.355 -0.150
ENSG00000070423 E012 22.6368019 0.0007069133 0.599551186 0.83738894 19 650234 650296 63 - 1.381 1.349 -0.111
ENSG00000070423 E013 4.6463049 0.0051967390 0.275991461 0.60420310 19 650297 650594 298 - 0.688 0.817 0.523
ENSG00000070423 E014 2.3387674 0.0066215773 0.219791535 0.54316398 19 651385 651610 226 - 0.438 0.612 0.827
ENSG00000070423 E015 25.5051516 0.0010698959 0.804676073 0.93323649 19 651611 651691 81 - 1.412 1.426 0.050
ENSG00000070423 E016 32.2212917 0.0006347301 0.288053416 0.61572287 19 651692 651784 93 - 1.538 1.483 -0.190
ENSG00000070423 E017 15.9361421 0.0079914588 0.236351039 0.56161010 19 651785 651822 38 - 1.261 1.165 -0.341
ENSG00000070423 E018 14.7084395 0.0435814383 0.291569872 0.61973299 19 651823 651855 33 - 1.237 1.116 -0.432
ENSG00000070423 E019 0.9461529 0.0158166250 0.422995668 0.72829159 19 651856 651915 60 - 0.335 0.209 -0.910
ENSG00000070423 E020 24.9312906 0.0005472025 0.583063707 0.82848132 19 652233 652296 64 - 1.421 1.389 -0.110
ENSG00000070423 E021 2.1923569 0.0080496657 0.613289942 0.84414825 19 652358 652825 468 - 0.468 0.541 0.353
ENSG00000070423 E022 20.7419540 0.0006966791 0.167328185 0.47377375 19 652826 652884 59 - 1.367 1.277 -0.312
ENSG00000070423 E023 0.0000000       19 661356 661402 47 -      
ENSG00000070423 E024 23.7797683 0.0006714253 0.040257076 0.21957127 19 663047 663233 187 - 1.333 1.455 0.423

Help

Please Click HERE to learn more details about the results from DEXseq.