ENSG00000071054

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000347699 ENSG00000071054 No_inf pgwt_inf MAP4K4 protein_coding protein_coding 110.7555 114.9891 93.75293 1.426691 2.197605 -0.2945331 14.364840 18.745793 12.398565 1.643091 1.0859682 -0.5960000 0.13078333 0.163400 0.132450 -0.030950 9.928472e-01 6.43381e-09 FALSE TRUE
ENST00000413150 ENSG00000071054 No_inf pgwt_inf MAP4K4 protein_coding protein_coding 110.7555 114.9891 93.75293 1.426691 2.197605 -0.2945331 26.281641 29.392192 20.451170 3.218737 2.4767175 -0.5230351 0.23657500 0.255600 0.217775 -0.037825 9.928472e-01 6.43381e-09 FALSE TRUE
MSTRG.16777.12 ENSG00000071054 No_inf pgwt_inf MAP4K4 protein_coding   110.7555 114.9891 93.75293 1.426691 2.197605 -0.2945331 10.644860 13.466510 6.140367 4.522360 2.5761481 -1.1317024 0.09472500 0.117475 0.067275 -0.050200 9.928472e-01 6.43381e-09 FALSE TRUE
MSTRG.16777.27 ENSG00000071054 No_inf pgwt_inf MAP4K4 protein_coding   110.7555 114.9891 93.75293 1.426691 2.197605 -0.2945331 15.343751 8.230540 16.558544 6.373621 2.4254313 1.0076360 0.13977500 0.071400 0.176625 0.105225 8.906867e-01 6.43381e-09 FALSE TRUE
MSTRG.16777.30 ENSG00000071054 No_inf pgwt_inf MAP4K4 protein_coding   110.7555 114.9891 93.75293 1.426691 2.197605 -0.2945331 6.103384 18.310152 0.000000 2.567055 0.0000000 -10.8392157 0.05305833 0.159175 0.000000 -0.159175 1.804753e-07 6.43381e-09 FALSE TRUE
MSTRG.16777.4 ENSG00000071054 No_inf pgwt_inf MAP4K4 protein_coding   110.7555 114.9891 93.75293 1.426691 2.197605 -0.2945331 8.474427 8.502453 6.382551 4.470191 3.7442860 -0.4131831 0.07660000 0.074150 0.069350 -0.004800 9.928472e-01 6.43381e-09 FALSE TRUE
MSTRG.16777.6 ENSG00000071054 No_inf pgwt_inf MAP4K4 protein_coding   110.7555 114.9891 93.75293 1.426691 2.197605 -0.2945331 11.168185 0.000000 16.137612 0.000000 0.6691559 10.6571051 0.10441667 0.000000 0.172175 0.172175 6.433810e-09 6.43381e-09 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000071054 E001 0.0000000       2 101696850 101697064 215 +      
ENSG00000071054 E002 0.2277562 1.540941e-02 2.031330e-01   2 101697583 101697654 72 + 0.182 0.000 -10.877
ENSG00000071054 E003 0.2281253 1.539987e-02 2.031216e-01   2 101697655 101697683 29 + 0.182 0.000 -13.215
ENSG00000071054 E004 0.4730802 1.544162e-02 2.637392e-01   2 101697684 101697693 10 + 0.250 0.090 -1.756
ENSG00000071054 E005 0.5876750 1.442799e-02 1.347045e-01   2 101697694 101697706 13 + 0.309 0.090 -2.171
ENSG00000071054 E006 1.5528487 8.713671e-03 1.090975e-01 3.812235e-01 2 101697707 101697723 17 + 0.523 0.284 -1.341
ENSG00000071054 E007 1.7983067 7.655185e-03 1.288690e-01 4.164405e-01 2 101697724 101697724 1 + 0.556 0.333 -1.171
ENSG00000071054 E008 3.3026855 4.688435e-03 6.137128e-01 8.444238e-01 2 101697725 101697743 19 + 0.666 0.602 -0.278
ENSG00000071054 E009 23.2940755 5.740262e-04 3.970139e-02 2.176811e-01 2 101697744 101698006 263 + 1.447 1.324 -0.428
ENSG00000071054 E010 14.7416144 2.303783e-03 7.216876e-02 3.051963e-01 2 101698007 101698025 19 + 1.265 1.129 -0.482
ENSG00000071054 E011 23.6966191 5.645719e-03 1.352241e-02 1.129228e-01 2 101698026 101698075 50 + 1.475 1.309 -0.573
ENSG00000071054 E012 18.3982819 8.225923e-03 8.707847e-02 3.382838e-01 2 101698076 101698080 5 + 1.353 1.222 -0.459
ENSG00000071054 E013 26.3229955 2.734234e-03 1.983543e-01 5.160595e-01 2 101698081 101698137 57 + 1.475 1.398 -0.265
ENSG00000071054 E014 29.2029399 4.513700e-04 3.480258e-01 6.687993e-01 2 101698473 101698529 57 + 1.504 1.454 -0.171
ENSG00000071054 E015 22.6196100 5.950143e-04 1.385483e-01 4.310483e-01 2 101698530 101698538 9 + 1.418 1.328 -0.311
ENSG00000071054 E016 43.3659560 3.058455e-04 1.837754e-02 1.373608e-01 2 101790720 101790776 57 + 1.700 1.594 -0.358
ENSG00000071054 E017 0.3779184 2.316609e-01 7.114817e-01   2 101797234 101797383 150 + 0.100 0.165 0.829
ENSG00000071054 E018 66.3293550 2.236720e-04 1.845510e-02 1.375178e-01 2 101823928 101824053 126 + 1.871 1.785 -0.288
ENSG00000071054 E019 55.5288687 1.382385e-03 2.844110e-02 1.784390e-01 2 101825319 101825401 83 + 1.798 1.706 -0.311
ENSG00000071054 E020 38.9537059 4.051646e-04 1.839502e-02 1.373806e-01 2 101825402 101825429 28 + 1.657 1.546 -0.379
ENSG00000071054 E021 72.0184627 2.291318e-04 6.882765e-06 3.055004e-04 2 101829504 101829594 91 + 1.942 1.784 -0.534
ENSG00000071054 E022 0.0000000       2 101829595 101829754 160 +      
ENSG00000071054 E023 101.3380578 1.418466e-04 1.242844e-04 3.513186e-03 2 101831721 101831851 131 + 2.067 1.953 -0.380
ENSG00000071054 E024 51.8621851 2.764316e-04 1.844913e-05 7.201399e-04 2 101834409 101834463 55 + 1.811 1.633 -0.600
ENSG00000071054 E025 70.6655241 6.041354e-04 1.714432e-04 4.527978e-03 2 101835900 101835978 79 + 1.924 1.787 -0.460
ENSG00000071054 E026 38.6873159 1.638000e-03 4.440361e-01 7.435784e-01 2 101839819 101839827 9 + 1.616 1.579 -0.125
ENSG00000071054 E027 110.3696005 1.731122e-03 3.096588e-01 6.359916e-01 2 101839828 101839994 167 + 2.061 2.029 -0.107
ENSG00000071054 E028 82.5310114 4.672465e-03 1.565123e-01 4.579785e-01 2 101842609 101842681 73 + 1.951 1.891 -0.201
ENSG00000071054 E029 168.6917100 2.869503e-04 1.907132e-02 1.397984e-01 2 101844101 101844311 211 + 2.256 2.202 -0.181
ENSG00000071054 E030 155.7355849 2.836987e-04 4.143186e-05 1.422672e-03 2 101855977 101856138 162 + 2.245 2.145 -0.334
ENSG00000071054 E031 102.5798949 2.822564e-03 7.361048e-03 7.601023e-02 2 101858996 101859082 87 + 2.064 1.967 -0.326
ENSG00000071054 E032 51.0363887 3.840499e-03 2.504896e-01 5.774738e-01 2 101859643 101859735 93 + 1.743 1.688 -0.185
ENSG00000071054 E033 110.8584186 1.351370e-04 9.222936e-03 8.820190e-02 2 101859736 101859864 129 + 2.085 2.012 -0.244
ENSG00000071054 E034 2.0845825 1.762559e-02 4.544045e-04 9.813880e-03 2 101859865 101860824 960 + 0.100 0.649 3.736
ENSG00000071054 E035 19.0636461 1.619342e-03 7.231821e-01 8.984461e-01 2 101860825 101860986 162 + 1.311 1.289 -0.078
ENSG00000071054 E036 3.6721184 5.556222e-03 3.625351e-02 2.067190e-01 2 101860987 101862240 1254 + 0.488 0.767 1.221
ENSG00000071054 E037 3.1285762 4.856683e-03 2.762001e-01 6.043730e-01 2 101863821 101864051 231 + 0.523 0.671 0.659
ENSG00000071054 E038 83.7991925 1.858234e-04 6.984495e-03 7.330544e-02 2 101864930 101865036 107 + 1.972 1.885 -0.293
ENSG00000071054 E039 28.0147248 7.098671e-03 3.356086e-02 1.967327e-01 2 101866428 101866430 3 + 1.531 1.394 -0.473
ENSG00000071054 E040 64.5932125 1.519374e-03 7.368768e-04 1.421950e-02 2 101866431 101866492 62 + 1.884 1.749 -0.455
ENSG00000071054 E041 75.7410185 1.908041e-04 1.371687e-06 7.483800e-05 2 101866493 101866579 87 + 1.967 1.801 -0.558
ENSG00000071054 E042 90.2084142 1.343256e-03 1.233634e-04 3.494595e-03 2 101867212 101867309 98 + 2.026 1.894 -0.445
ENSG00000071054 E043 4.6342370 3.114143e-03 1.520561e-01 4.513308e-01 2 101867310 101867535 226 + 0.641 0.815 0.714
ENSG00000071054 E044 8.1865414 2.947955e-02 3.114304e-02 1.884486e-01 2 101867536 101867855 320 + 0.792 1.056 0.999
ENSG00000071054 E045 3.9149908 1.192219e-02 5.115437e-02 2.510707e-01 2 101867856 101868028 173 + 0.523 0.784 1.119
ENSG00000071054 E046 9.8560113 1.369808e-03 1.459484e-03 2.392039e-02 2 101868029 101868037 9 + 1.169 0.886 -1.041
ENSG00000071054 E047 149.8684213 1.325156e-04 1.537665e-02 1.223098e-01 2 101869622 101869797 176 + 2.207 2.149 -0.195
ENSG00000071054 E048 5.6124568 6.940198e-03 2.333838e-01 5.587881e-01 2 101869798 101870085 288 + 0.734 0.873 0.549
ENSG00000071054 E049 146.8799873 7.320509e-04 1.975525e-02 1.429952e-01 2 101870295 101870415 121 + 2.200 2.139 -0.205
ENSG00000071054 E050 2.0830951 2.011145e-02 4.828071e-04 1.029329e-02 2 101870416 101870633 218 + 0.100 0.649 3.736
ENSG00000071054 E051 65.0683469 2.393196e-04 2.185651e-01 5.417125e-01 2 101871494 101871685 192 + 1.841 1.797 -0.149
ENSG00000071054 E052 140.5968339 1.179908e-04 1.720721e-01 4.808959e-01 2 101873647 101873764 118 + 2.166 2.133 -0.110
ENSG00000071054 E053 176.3472134 2.470092e-04 2.442934e-02 1.630486e-01 2 101874082 101874252 171 + 2.273 2.222 -0.169
ENSG00000071054 E054 196.9019966 1.243925e-04 8.782202e-01 9.613298e-01 2 101877003 101877146 144 + 2.294 2.292 -0.005
ENSG00000071054 E055 233.1166982 7.754009e-05 8.858667e-01 9.643328e-01 2 101882551 101882685 135 + 2.366 2.365 -0.003
ENSG00000071054 E056 190.4070395 8.206417e-05 9.976743e-01 1.000000e+00 2 101885187 101885287 101 + 2.277 2.279 0.007
ENSG00000071054 E057 251.5558855 7.359420e-05 7.989059e-01 9.308762e-01 2 101887088 101887237 150 + 2.400 2.397 -0.010
ENSG00000071054 E058 30.0486354 5.140462e-04 4.427724e-01 7.426817e-01 2 101887238 101887261 24 + 1.463 1.507 0.151
ENSG00000071054 E059 274.3257049 4.439357e-04 8.459980e-02 3.327947e-01 2 101887778 101887937 160 + 2.415 2.452 0.121
ENSG00000071054 E060 268.5269207 7.090409e-05 1.780292e-03 2.787041e-02 2 101888796 101888935 140 + 2.392 2.452 0.200
ENSG00000071054 E061 1204.2070906 1.028337e-04 5.172836e-84 3.051169e-80 2 101891166 101894751 3586 + 2.974 3.143 0.565

Help

Please Click HERE to learn more details about the results from DEXseq.