ENSG00000075391

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000462775 ENSG00000075391 No_inf pgwt_inf RASAL2 protein_coding protein_coding 32.49166 40.74502 24.86781 1.681355 0.866564 -0.7121181 4.635103 7.742229 1.562301 1.106614 1.1204386 -2.301733747 0.13395000 0.191425 0.066350 -0.125075 0.845567008 0.003531005 FALSE TRUE
ENST00000463079 ENSG00000075391 No_inf pgwt_inf RASAL2 protein_coding retained_intron 32.49166 40.74502 24.86781 1.681355 0.866564 -0.7121181 10.830281 10.276479 10.268561 1.113054 0.7873100 -0.001110906 0.34462500 0.252600 0.411200 0.158600 0.953282237 0.003531005 FALSE FALSE
MSTRG.2301.1 ENSG00000075391 No_inf pgwt_inf RASAL2 protein_coding   32.49166 40.74502 24.86781 1.681355 0.866564 -0.7121181 7.793814 5.214150 7.858763 1.073123 1.0836306 0.590940326 0.25690833 0.126450 0.314925 0.188475 0.692432885 0.003531005 FALSE TRUE
MSTRG.2301.14 ENSG00000075391 No_inf pgwt_inf RASAL2 protein_coding   32.49166 40.74502 24.86781 1.681355 0.866564 -0.7121181 1.379836 4.139508 0.000000 1.106707 0.0000000 -8.696796393 0.03383333 0.101500 0.000000 -0.101500 0.003531005 0.003531005 FALSE TRUE
MSTRG.2301.2 ENSG00000075391 No_inf pgwt_inf RASAL2 protein_coding   32.49166 40.74502 24.86781 1.681355 0.866564 -0.7121181 2.012714 2.832103 1.093460 1.163451 0.6548978 -1.364924675 0.06010833 0.069850 0.042225 -0.027625 0.992847247 0.003531005   FALSE
MSTRG.2301.4 ENSG00000075391 No_inf pgwt_inf RASAL2 protein_coding   32.49166 40.74502 24.86781 1.681355 0.866564 -0.7121181 1.731781 3.403400 1.222869 1.388722 0.5293777 -1.469190070 0.05050000 0.084700 0.050850 -0.033850 0.992847247 0.003531005 TRUE FALSE
MSTRG.2301.7 ENSG00000075391 No_inf pgwt_inf RASAL2 protein_coding   32.49166 40.74502 24.86781 1.681355 0.866564 -0.7121181 1.075034 3.225101 0.000000 2.039633 0.0000000 -8.337666974 0.02490000 0.074700 0.000000 -0.074700 0.992847247 0.003531005   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000075391 E001 1.2269098 1.152951e-02 4.652260e-01 7.575529e-01 1 178094013 178094049 37 + 0.407 0.294 -0.682
ENSG00000075391 E002 2.4545002 5.950763e-03 3.019538e-01 6.289798e-01 1 178094050 178094103 54 + 0.613 0.467 -0.682
ENSG00000075391 E003 6.2249318 7.013626e-03 5.435182e-05 1.788792e-03 1 178094104 178094224 121 + 1.074 0.632 -1.724
ENSG00000075391 E004 24.6337391 1.253517e-02 3.121154e-04 7.312229e-03 1 178094225 178094694 470 + 1.545 1.274 -0.939
ENSG00000075391 E005 0.3766167 1.654565e-02 9.332157e-01   1 178120961 178121087 127 + 0.117 0.142 0.318
ENSG00000075391 E006 1.9822184 7.437692e-03 6.698774e-01 8.723637e-01 1 178123056 178123182 127 + 0.501 0.438 -0.319
ENSG00000075391 E007 0.9301698 1.509479e-02 4.529642e-03 5.426779e-02 1 178123719 178123815 97 + 0.501 0.077 -3.489
ENSG00000075391 E008 1.0486197 4.867136e-01 1.175198e-01 3.967600e-01 1 178125182 178125326 145 + 0.000 0.406 12.284
ENSG00000075391 E009 2.6356694 5.789935e-03 6.305334e-01 8.522391e-01 1 178125327 178125501 175 + 0.501 0.569 0.318
ENSG00000075391 E010 0.6391391 1.424112e-02 3.897950e-01   1 178132790 178132837 48 + 0.117 0.249 1.318
ENSG00000075391 E011 72.9480102 2.055919e-04 6.622758e-09 5.869378e-07 1 178134565 178137465 2901 + 1.693 1.915 0.747
ENSG00000075391 E012 1.9961840 9.153463e-03 9.401302e-01 9.845292e-01 1 178230310 178233880 3571 + 0.456 0.467 0.055
ENSG00000075391 E013 12.4352964 9.168185e-02 4.083919e-01 7.174495e-01 1 178283564 178283691 128 + 1.201 1.051 -0.538
ENSG00000075391 E014 12.4979473 1.214157e-02 2.491452e-02 1.652232e-01 1 178299992 178300118 127 + 1.234 1.028 -0.738
ENSG00000075391 E015 0.3596429 1.654158e-02 3.334791e-01   1 178341471 178341608 138 + 0.210 0.077 -1.682
ENSG00000075391 E016 0.0000000       1 178371374 178371475 102 +      
ENSG00000075391 E017 0.1139502 1.111283e-02 3.293957e-01   1 178372203 178372322 120 + 0.117 0.000 -12.146
ENSG00000075391 E018 0.3763212 2.041647e-01 1.000000e+00   1 178389010 178389307 298 + 0.117 0.142 0.318
ENSG00000075391 E019 11.8151232 1.093030e-03 6.204179e-02 2.802711e-01 1 178390100 178390206 107 + 1.184 1.028 -0.561
ENSG00000075391 E020 11.4155472 1.818239e-03 3.417327e-02 1.990899e-01 1 178420511 178420620 110 + 1.184 1.004 -0.651
ENSG00000075391 E021 16.8696850 8.074838e-04 3.391751e-02 1.981451e-01 1 178439422 178439575 154 + 1.325 1.174 -0.534
ENSG00000075391 E022 12.3794926 1.262146e-03 1.531915e-02 1.219971e-01 1 178441549 178441647 99 + 1.226 1.028 -0.710
ENSG00000075391 E023 57.1873120 3.054247e-03 7.620046e-03 7.767238e-02 1 178442675 178443229 555 + 1.820 1.698 -0.413
ENSG00000075391 E024 20.6040769 1.387765e-03 4.870770e-02 2.437267e-01 1 178445518 178445662 145 + 1.396 1.265 -0.457
ENSG00000075391 E025 21.1074980 6.526250e-04 2.298978e-03 3.363008e-02 1 178451571 178451715 145 + 1.442 1.246 -0.682
ENSG00000075391 E026 7.8580260 1.715573e-03 9.534156e-01 9.886103e-01 1 178452416 178452436 21 + 0.926 0.931 0.019
ENSG00000075391 E027 28.0650643 4.784937e-04 4.284933e-03 5.225591e-02 1 178452437 178452652 216 + 1.542 1.380 -0.555
ENSG00000075391 E028 28.7738567 3.904806e-03 4.505199e-02 2.330209e-01 1 178454447 178454648 202 + 1.530 1.407 -0.421
ENSG00000075391 E029 6.5530897 2.056530e-03 2.520054e-01 5.789319e-01 1 178456475 178456699 225 + 0.775 0.901 0.488
ENSG00000075391 E030 10.5872252 1.374380e-02 1.264669e-01 4.121314e-01 1 178456700 178456720 21 + 1.137 0.987 -0.547
ENSG00000075391 E031 40.8010236 3.469062e-04 1.325677e-04 3.689423e-03 1 178456721 178456899 179 + 1.710 1.530 -0.612
ENSG00000075391 E032 124.2188060 1.256733e-04 2.153054e-07 1.400120e-05 1 178457683 178458544 862 + 2.163 2.024 -0.466
ENSG00000075391 E033 0.2626639 1.606871e-02 4.505428e-01   1 178459045 178459078 34 + 0.000 0.142 11.184
ENSG00000075391 E034 23.4295274 6.150675e-04 1.018387e-03 1.821361e-02 1 178464278 178464412 135 + 1.488 1.287 -0.697
ENSG00000075391 E035 47.4696858 3.144239e-04 1.135300e-02 1.009119e-01 1 178465920 178466122 203 + 1.735 1.623 -0.380
ENSG00000075391 E036 31.8844492 1.158164e-02 1.923093e-02 1.404580e-01 1 178467334 178467421 88 + 1.596 1.433 -0.559
ENSG00000075391 E037 0.6049571 1.889031e-02 3.365971e-01   1 178470693 178470723 31 + 0.286 0.142 -1.267
ENSG00000075391 E038 987.1100408 8.649801e-05 5.980593e-34 5.039457e-31 1 178473075 178484147 11073 + 2.921 3.001 0.268

Help

Please Click HERE to learn more details about the results from DEXseq.