ENSG00000076928

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000354532 ENSG00000076928 No_inf pgwt_inf ARHGEF1 protein_coding protein_coding 146.543 261.2974 88.73471 15.67364 2.074816 -1.558015 39.267678 44.54924 33.039139 1.9637086 1.6462122 -0.4311121 0.33538333 0.171650 0.373275 0.201625 4.447282e-01 1.539295e-05 FALSE TRUE
ENST00000595723 ENSG00000076928 No_inf pgwt_inf ARHGEF1 protein_coding protein_coding 146.543 261.2974 88.73471 15.67364 2.074816 -1.558015 12.329541 21.43355 9.111293 8.2310403 4.5692322 -1.2332333 0.07752500 0.077475 0.101925 0.024450 1.000000e+00 1.539295e-05 FALSE TRUE
ENST00000598444 ENSG00000076928 No_inf pgwt_inf ARHGEF1 protein_coding retained_intron 146.543 261.2974 88.73471 15.67364 2.074816 -1.558015 8.449612 20.99103 0.000000 4.1279778 0.0000000 -11.0362445 0.04367500 0.079075 0.000000 -0.079075 1.539295e-05 1.539295e-05 FALSE FALSE
ENST00000617585 ENSG00000076928 No_inf pgwt_inf ARHGEF1 protein_coding retained_intron 146.543 261.2974 88.73471 15.67364 2.074816 -1.558015 19.448046 40.57115 10.495125 3.3145669 0.6734215 -1.9497166 0.11995833 0.156475 0.118275 -0.038200 9.928472e-01 1.539295e-05 FALSE FALSE
MSTRG.15225.1 ENSG00000076928 No_inf pgwt_inf ARHGEF1 protein_coding   146.543 261.2974 88.73471 15.67364 2.074816 -1.558015 12.277899 26.23882 7.128761 0.7703186 0.9510871 -1.8785071 0.07421667 0.101200 0.080600 -0.020600 9.928472e-01 1.539295e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000076928 E001 0.1316618 0.0122927288 1.000000e+00   19 41883173 41883182 10 + 0.000 0.065 9.570
ENSG00000076928 E002 0.1316618 0.0122927288 1.000000e+00   19 41883183 41883183 1 + 0.000 0.065 12.164
ENSG00000076928 E003 0.4748017 0.0279908604 7.367766e-02   19 41883184 41883199 16 + 0.323 0.065 -2.764
ENSG00000076928 E004 1.0798165 0.0120311006 2.856728e-02 1.788712e-01 19 41883200 41883203 4 + 0.507 0.173 -2.179
ENSG00000076928 E005 1.4726918 0.0094769633 1.691725e-01 4.764040e-01 19 41883204 41883204 1 + 0.507 0.296 -1.179
ENSG00000076928 E006 10.6942127 0.0122828139 7.957480e-02 3.222411e-01 19 41883205 41883223 19 + 1.143 0.968 -0.636
ENSG00000076928 E007 11.4475166 0.0079252801 7.356753e-02 3.079973e-01 19 41883224 41883224 1 + 1.165 0.998 -0.607
ENSG00000076928 E008 21.6012933 0.0007642437 5.626766e-02 2.652012e-01 19 41883225 41883289 65 + 1.397 1.269 -0.446
ENSG00000076928 E009 0.4741445 0.0312515929 7.394228e-02   19 41884370 41884373 4 + 0.323 0.065 -2.764
ENSG00000076928 E010 0.7020449 0.0144464262 8.341526e-03 8.241545e-02 19 41884374 41884396 23 + 0.454 0.065 -3.501
ENSG00000076928 E011 1.2101131 0.0104232134 5.910163e-02 2.731084e-01 19 41884397 41884424 28 + 0.507 0.218 -1.764
ENSG00000076928 E012 1.2271703 0.0109901884 2.093166e-01 5.300916e-01 19 41884425 41884447 23 + 0.454 0.259 -1.179
ENSG00000076928 E013 1.8153552 0.0081704165 2.105646e-02 1.487033e-01 19 41884448 41884493 46 + 0.635 0.296 -1.764
ENSG00000076928 E014 24.4618802 0.0007509470 3.723660e-02 2.097770e-01 19 41888064 41888106 43 + 1.451 1.319 -0.458
ENSG00000076928 E015 39.2037391 0.0004040365 9.786626e-03 9.143485e-02 19 41888192 41888278 87 + 1.648 1.517 -0.447
ENSG00000076928 E016 53.0518679 0.0090502827 8.870980e-02 3.417686e-01 19 41888752 41888865 114 + 1.759 1.654 -0.354
ENSG00000076928 E017 17.4025711 0.0008706770 1.326590e-01 4.220506e-01 19 41888866 41890776 1911 + 1.131 1.249 0.420
ENSG00000076928 E018 41.9052116 0.0004457028 2.919965e-03 3.999207e-02 19 41892025 41892123 99 + 1.686 1.540 -0.497
ENSG00000076928 E019 5.8612395 0.0042625474 2.764685e-01 6.045896e-01 19 41892124 41892330 207 + 0.883 0.757 -0.491
ENSG00000076928 E020 30.1132681 0.0004764169 3.997653e-02 2.186026e-01 19 41892331 41892373 43 + 1.529 1.410 -0.407
ENSG00000076928 E021 0.2633236 0.2850695091 7.703570e-01   19 41892374 41892528 155 + 0.000 0.122 12.259
ENSG00000076928 E022 26.7874288 0.0005365627 5.919239e-01 8.334160e-01 19 41892603 41892633 31 + 1.422 1.388 -0.117
ENSG00000076928 E023 75.0829352 0.0047348634 9.980296e-02 3.643668e-01 19 41892634 41892849 216 + 1.888 1.811 -0.258
ENSG00000076928 E024 0.3771270 0.0167090893 9.240642e-01   19 41893190 41893273 84 + 0.136 0.122 -0.179
ENSG00000076928 E025 26.1817272 0.0027631979 8.623941e-01 9.558430e-01 19 41893274 41893303 30 + 1.397 1.385 -0.041
ENSG00000076928 E026 51.7075981 0.0003064542 6.024719e-01 8.386518e-01 19 41894207 41894291 85 + 1.692 1.668 -0.083
ENSG00000076928 E027 35.4134110 0.0017959737 3.601970e-01 6.797276e-01 19 41894292 41894306 15 + 1.552 1.500 -0.179
ENSG00000076928 E028 45.4461278 0.0009902852 5.454761e-02 2.610634e-01 19 41894451 41894486 36 + 1.686 1.592 -0.320
ENSG00000076928 E029 56.2690454 0.0020723416 8.813108e-02 3.407521e-01 19 41894487 41894547 61 + 1.767 1.687 -0.269
ENSG00000076928 E030 39.9581757 0.0011053839 9.990424e-02 3.645233e-01 19 41894626 41894661 36 + 1.626 1.540 -0.293
ENSG00000076928 E031 40.5142819 0.0003972610 2.854140e-02 1.788419e-01 19 41895349 41895378 30 + 1.648 1.538 -0.375
ENSG00000076928 E032 75.0085937 0.0002520061 1.388935e-02 1.150819e-01 19 41895379 41895486 108 + 1.898 1.806 -0.311
ENSG00000076928 E033 65.2657684 0.0016997631 4.390298e-02 2.303225e-01 19 41896377 41896482 106 + 1.835 1.748 -0.294
ENSG00000076928 E034 56.6216487 0.0010810106 2.256479e-08 1.826028e-06 19 41896483 41896878 396 + 1.494 1.775 0.955
ENSG00000076928 E035 15.4384483 0.0009250688 2.461169e-02 1.638085e-01 19 41897315 41897326 12 + 1.024 1.216 0.691
ENSG00000076928 E036 45.8670839 0.0002973617 1.520665e-07 1.020557e-05 19 41897327 41897674 348 + 1.403 1.686 0.967
ENSG00000076928 E037 37.1647563 0.0003812164 1.724481e-06 9.197797e-05 19 41897675 41897810 136 + 1.312 1.597 0.982
ENSG00000076928 E038 43.9318962 0.0003815836 1.371545e-03 2.288179e-02 19 41897811 41897945 135 + 1.479 1.646 0.573
ENSG00000076928 E039 24.5933219 0.0005612543 1.816208e-01 4.943609e-01 19 41897946 41897982 37 + 1.296 1.385 0.309
ENSG00000076928 E040 54.9807800 0.0003304214 4.131450e-05 1.419561e-03 19 41897983 41898113 131 + 1.552 1.747 0.663
ENSG00000076928 E041 79.5945569 0.0001937704 1.398188e-12 2.126769e-10 19 41898114 41898423 310 + 1.630 1.923 0.990
ENSG00000076928 E042 20.1229465 0.0069026597 3.926656e-06 1.877932e-04 19 41898424 41898441 18 + 0.941 1.361 1.506
ENSG00000076928 E043 116.0959342 0.0038156455 2.399832e-01 5.657584e-01 19 41898442 41898587 146 + 2.054 2.007 -0.158
ENSG00000076928 E044 0.3943257 0.0159552997 3.843704e-01   19 41900836 41900933 98 + 0.000 0.173 13.691
ENSG00000076928 E045 110.7707249 0.0012673139 9.322386e-01 9.810451e-01 19 41901887 41902026 140 + 2.004 2.000 -0.013
ENSG00000076928 E046 32.7595513 0.0025152706 4.056099e-01 7.153589e-01 19 41902027 41902033 7 + 1.445 1.495 0.171
ENSG00000076928 E047 89.3750371 0.0001651476 1.903992e-01 5.049838e-01 19 41902274 41902356 83 + 1.875 1.921 0.153
ENSG00000076928 E048 130.7113677 0.0001189692 5.472316e-01 8.092467e-01 19 41902533 41902658 126 + 2.060 2.077 0.056
ENSG00000076928 E049 53.7237087 0.0002501695 6.019658e-01 8.386141e-01 19 41902784 41902797 14 + 1.708 1.684 -0.081
ENSG00000076928 E050 110.2701092 0.0001431843 2.741628e-01 6.022520e-01 19 41902798 41902898 101 + 2.024 1.989 -0.117
ENSG00000076928 E051 116.6453962 0.0003762680 2.373075e-02 1.601987e-01 19 41903307 41903407 101 + 2.072 2.003 -0.234
ENSG00000076928 E052 3.4956320 0.0721468426 4.080811e-02 2.213440e-01 19 41903656 41903706 51 + 0.323 0.691 1.822
ENSG00000076928 E053 100.5573998 0.0001807791 5.466700e-01 8.089887e-01 19 41903707 41903784 78 + 1.974 1.953 -0.069
ENSG00000076928 E054 95.5329471 0.0021532623 9.738443e-01 9.954844e-01 19 41904035 41904110 76 + 1.937 1.937 0.002
ENSG00000076928 E055 145.1902209 0.0004451408 1.996192e-01 5.178103e-01 19 41904216 41904383 168 + 2.143 2.107 -0.122
ENSG00000076928 E056 107.0156294 0.0007817899 7.072573e-01 8.908251e-01 19 41904949 41905036 88 + 1.996 1.982 -0.044
ENSG00000076928 E057 116.7767060 0.0001306833 4.621065e-01 7.557271e-01 19 41905175 41905261 87 + 2.040 2.017 -0.077
ENSG00000076928 E058 3.6242700 0.0041652978 1.263115e-02 1.081163e-01 19 41905513 41905589 77 + 0.323 0.705 1.880
ENSG00000076928 E059 6.1907770 0.0202089360 7.778480e-01 9.227451e-01 19 41905590 41905759 170 + 0.789 0.826 0.143
ENSG00000076928 E060 74.4887040 0.0001982450 9.772139e-01 9.965816e-01 19 41905760 41905799 40 + 1.830 1.831 0.001
ENSG00000076928 E061 62.8911136 0.0002338877 4.480015e-01 7.463891e-01 19 41905800 41905827 28 + 1.736 1.767 0.105
ENSG00000076928 E062 94.1788319 0.0021432312 7.012469e-01 8.876226e-01 19 41905939 41906025 87 + 1.942 1.927 -0.053
ENSG00000076928 E063 25.3709771 0.0005292562 3.475876e-11 4.457013e-09 19 41906026 41906335 310 + 0.941 1.469 1.880
ENSG00000076928 E064 78.7479196 0.0001816874 4.397802e-01 7.405067e-01 19 41906457 41906575 119 + 1.875 1.846 -0.099
ENSG00000076928 E065 48.0504044 0.0011868005 8.402427e-01 9.470700e-01 19 41906576 41906620 45 + 1.637 1.646 0.031
ENSG00000076928 E066 2.6723484 0.0061271416 4.898743e-01 7.742257e-01 19 41906621 41906702 82 + 0.454 0.557 0.499
ENSG00000076928 E067 88.0949273 0.0001723982 9.708500e-01 9.945110e-01 19 41906703 41906803 101 + 1.902 1.903 0.002
ENSG00000076928 E068 15.6557384 0.0100939414 2.118624e-03 3.169935e-02 19 41906804 41907104 301 + 0.941 1.241 1.087
ENSG00000076928 E069 153.6332547 0.0001339231 9.995672e-01 1.000000e+00 19 41907105 41907454 350 + 2.142 2.141 -0.003
ENSG00000076928 E070 0.0000000       19 41923092 41923093 2 +      
ENSG00000076928 E071 0.1316618 0.0122927288 1.000000e+00   19 41923094 41923211 118 + 0.000 0.065 12.164
ENSG00000076928 E072 0.2628107 0.0161155106 6.919183e-01   19 41923212 41923233 22 + 0.000 0.122 13.122
ENSG00000076928 E073 0.2623781 0.0160945995 6.919207e-01   19 41928590 41928722 133 + 0.000 0.122 13.122
ENSG00000076928 E074 0.0000000       19 41928820 41928830 11 +      
ENSG00000076928 E075 0.0000000       19 41928831 41928853 23 +      
ENSG00000076928 E076 0.3931610 0.0290184041 3.877229e-01   19 41928854 41928986 133 + 0.000 0.173 13.616
ENSG00000076928 E077 0.9181226 0.2299575388 1.205258e-01 4.018235e-01 19 41929655 41930150 496 + 0.000 0.330 14.118

Help

Please Click HERE to learn more details about the results from DEXseq.