ENSG00000077044

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264057 ENSG00000077044 No_inf pgwt_inf DGKD protein_coding protein_coding 25.13187 35.36886 21.27413 3.201797 0.4290163 -0.7331096 8.852155 7.1846167 10.578792 0.6138976 0.6076825 0.5575483 0.38732500 0.206000 0.49745 0.291450 0.281481962 0.000102003 FALSE TRUE
ENST00000430834 ENSG00000077044 No_inf pgwt_inf DGKD protein_coding nonsense_mediated_decay 25.13187 35.36886 21.27413 3.201797 0.4290163 -0.7331096 7.645397 12.4918815 4.703732 0.9737827 0.7769285 -1.4072037 0.29939167 0.360925 0.22190 -0.139025 0.992847247 0.000102003 FALSE TRUE
ENST00000471764 ENSG00000077044 No_inf pgwt_inf DGKD protein_coding retained_intron 25.13187 35.36886 21.27413 3.201797 0.4290163 -0.7331096 2.831587 8.4947610 0.000000 2.7441900 0.0000000 -9.7321269 0.07592500 0.227775 0.00000 -0.227775 0.000102003 0.000102003   FALSE
ENST00000480535 ENSG00000077044 No_inf pgwt_inf DGKD protein_coding protein_coding_CDS_not_defined 25.13187 35.36886 21.27413 3.201797 0.4290163 -0.7331096 1.079921 0.5618916 1.454368 0.0194656 0.8587771 1.3564646 0.04841667 0.016350 0.06785 0.051500 0.997345511 0.000102003   FALSE
ENST00000495901 ENSG00000077044 No_inf pgwt_inf DGKD protein_coding retained_intron 25.13187 35.36886 21.27413 3.201797 0.4290163 -0.7331096 2.190412 3.5069403 2.344634 0.9607704 0.8619016 -0.5788178 0.08254167 0.098550 0.11110 0.012550 1.000000000 0.000102003   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000077044 E001 0.4566703 0.0161192359 0.0266988269   2 233354494 233354507 14 + 0.321 0.000 -11.444
ENSG00000077044 E002 2.8088084 0.0166317052 0.0001737738 0.004584968 2 233354508 233354571 64 + 0.811 0.273 -2.640
ENSG00000077044 E003 4.6939163 0.0093537107 0.0190181408 0.139524188 2 233354572 233354674 103 + 0.894 0.610 -1.155
ENSG00000077044 E004 0.0000000       2 233385945 233386010 66 +      
ENSG00000077044 E005 0.0000000       2 233386054 233386214 161 +      
ENSG00000077044 E006 0.0000000       2 233388154 233388256 103 +      
ENSG00000077044 E007 6.1015007 0.0025019359 0.1882764167 0.502579352 2 233388257 233388367 111 + 0.923 0.781 -0.550
ENSG00000077044 E008 0.2279004 0.2765854894 0.2324317208   2 233388368 233388985 618 + 0.189 0.000 -12.235
ENSG00000077044 E009 5.1035869 0.0027754546 0.1073591332 0.378542491 2 233390403 233390483 81 + 0.879 0.694 -0.733
ENSG00000077044 E010 1.0144442 0.0137118850 0.2569056171 0.584553998 2 233392070 233392399 330 + 0.189 0.365 1.267
ENSG00000077044 E011 0.1139502 0.0111847340 0.4326629761   2 233408891 233409051 161 + 0.105 0.000 -12.011
ENSG00000077044 E012 0.7198497 0.0143547824 0.2822260592 0.610026571 2 233419241 233419421 181 + 0.321 0.158 -1.318
ENSG00000077044 E013 8.0151389 0.0031139891 0.0385474468 0.214073623 2 233434380 233434466 87 + 1.056 0.854 -0.759
ENSG00000077044 E014 5.4794753 0.0026262499 0.1455567387 0.441201249 2 233434467 233434484 18 + 0.894 0.731 -0.640
ENSG00000077044 E015 10.3704788 0.0013315813 0.0810349250 0.325402423 2 233434769 233434901 133 + 1.133 0.980 -0.557
ENSG00000077044 E016 9.0290485 0.0029298245 0.1104046096 0.383669750 2 233435818 233435924 107 + 1.077 0.927 -0.553
ENSG00000077044 E017 11.4663234 0.0381668279 0.1566815843 0.458320398 2 233436316 233436441 126 + 1.174 1.018 -0.564
ENSG00000077044 E018 7.9643954 0.0021525297 0.3252609855 0.649684546 2 233437377 233437479 103 + 1.001 0.904 -0.363
ENSG00000077044 E019 6.0166671 0.0023453736 0.0064189894 0.068979448 2 233438217 233438312 96 + 0.989 0.694 -1.148
ENSG00000077044 E020 6.3489436 0.0022616244 0.1868976487 0.500916271 2 233438313 233438379 67 + 0.937 0.797 -0.541
ENSG00000077044 E021 9.6838416 0.0014576557 0.2871688469 0.614895665 2 233441887 233441995 109 + 1.077 0.980 -0.355
ENSG00000077044 E022 2.4524021 0.0059276357 0.6333018532 0.853805927 2 233441996 233442591 596 + 0.572 0.504 -0.318
ENSG00000077044 E023 11.8404830 0.0048823647 0.0905508092 0.345388696 2 233445623 233445762 140 + 1.182 1.036 -0.527
ENSG00000077044 E024 7.8929494 0.0072217717 0.1360764463 0.427238835 2 233446712 233446796 85 + 0.846 1.000 0.580
ENSG00000077044 E025 3.2077023 0.0984242778 0.9057009056 0.972238474 2 233447701 233447905 205 + 0.632 0.610 -0.096
ENSG00000077044 E026 1.1495028 0.0618201572 0.1855133365 0.499247743 2 233448030 233448086 57 + 0.189 0.404 1.489
ENSG00000077044 E027 8.4655212 0.0126045238 0.4492749029 0.747397684 2 233448087 233448181 95 + 0.923 1.000 0.284
ENSG00000077044 E028 13.2648241 0.0019441224 0.0195238945 0.141901076 2 233448276 233448375 100 + 1.247 1.062 -0.664
ENSG00000077044 E029 25.1203595 0.0009605181 0.4044286419 0.714698882 2 233449103 233449376 274 + 1.440 1.388 -0.177
ENSG00000077044 E030 12.7940646 0.0011725319 0.4802714746 0.767824098 2 233449982 233450131 150 + 1.166 1.109 -0.207
ENSG00000077044 E031 11.3550668 0.0012183918 0.8420056423 0.947755813 2 233450922 233451050 129 + 1.096 1.078 -0.067
ENSG00000077044 E032 11.2796415 0.0012768177 0.7368804942 0.904432676 2 233451964 233452060 97 + 1.067 1.093 0.097
ENSG00000077044 E033 0.6219309 0.0186351090 0.8375919747   2 233454357 233454464 108 + 0.189 0.220 0.267
ENSG00000077044 E034 14.4344194 0.0114083797 0.7746033852 0.921573180 2 233454763 233454873 111 + 1.198 1.171 -0.096
ENSG00000077044 E035 13.8902539 0.0564184776 0.6010992147 0.838141872 2 233456899 233456995 97 + 1.205 1.137 -0.242
ENSG00000077044 E036 10.8254269 0.0013467150 0.4117891692 0.720063193 2 233457221 233457328 108 + 1.024 1.093 0.253
ENSG00000077044 E037 6.8671569 0.0062254407 0.0023933050 0.034571698 2 233457329 233457817 489 + 0.658 1.000 1.339
ENSG00000077044 E038 1.1643256 0.0125487768 0.0312921575 0.188984696 2 233458239 233458283 45 + 0.105 0.440 2.682
ENSG00000077044 E039 11.3925343 0.0013372283 0.8267636088 0.941412088 2 233458284 233458397 114 + 1.077 1.093 0.060
ENSG00000077044 E040 20.8415804 0.0027201143 0.6937535551 0.883753499 2 233459757 233459891 135 + 1.349 1.321 -0.096
ENSG00000077044 E041 20.5650780 0.0009389044 0.4862667474 0.772124134 2 233460194 233460345 152 + 1.354 1.307 -0.163
ENSG00000077044 E042 17.3288406 0.0008675458 0.8051341268 0.933373657 2 233462348 233462459 112 + 1.247 1.263 0.055
ENSG00000077044 E043 16.9141209 0.0007904473 0.3262747202 0.650686344 2 233462643 233462735 93 + 1.205 1.273 0.240
ENSG00000077044 E044 5.5990477 0.0140379233 0.5659727708 0.818926730 2 233463814 233464163 350 + 0.772 0.840 0.267
ENSG00000077044 E045 20.0593379 0.0088816933 0.2240185074 0.548224131 2 233464164 233464283 120 + 1.261 1.352 0.319
ENSG00000077044 E046 20.9285277 0.0006803146 0.1619753609 0.465621054 2 233467086 233467203 118 + 1.280 1.369 0.310
ENSG00000077044 E047 21.2534494 0.0010213470 0.3347764430 0.657854609 2 233468423 233468553 131 + 1.304 1.364 0.211
ENSG00000077044 E048 339.1323636 0.0001424899 0.0002403602 0.005956939 2 233469371 233472104 2734 + 2.498 2.542 0.149

Help

Please Click HERE to learn more details about the results from DEXseq.