ENSG00000077585

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000366592 ENSG00000077585 No_inf pgwt_inf GPR137B protein_coding protein_coding 37.48802 15.62615 49.4434 1.139957 1.558478 1.661184 30.051750 10.5826225 43.876942 0.7314788 0.4501079 2.050732 0.7810667 0.700025 0.890650 0.190625 0.99284725 0.04950343 FALSE TRUE
ENST00000419162 ENSG00000077585 No_inf pgwt_inf GPR137B protein_coding nonsense_mediated_decay 37.48802 15.62615 49.4434 1.139957 1.558478 1.661184 3.802926 0.8118354 5.305426 0.8118354 1.9331408 2.693264 0.0871500 0.047075 0.103975 0.056900 0.84407772 0.04950343 TRUE TRUE
ENST00000454895 ENSG00000077585 No_inf pgwt_inf GPR137B protein_coding protein_coding 37.48802 15.62615 49.4434 1.139957 1.558478 1.661184 3.491220 4.2316948 0.000000 1.4203333 0.0000000 -8.728497 0.1288167 0.252900 0.000000 -0.252900 0.04950343 0.04950343 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000077585 E001 0.8157901 0.0128895428 5.453501e-01 0.8082105744 1 236142505 236142538 34 + 0.262 0.157 -0.928
ENSG00000077585 E002 0.7991020 0.0126384646 1.251790e-01 0.4100883719 1 236142539 236142543 5 + 0.293 0.000 -13.042
ENSG00000077585 E003 53.7376693 0.0002834925 2.452357e-06 0.0001244606 1 236142544 236143036 493 + 1.736 1.509 -0.773
ENSG00000077585 E004 0.1311489 0.0124070156 1.414812e-01   1 236168701 236168705 5 + 0.000 0.157 12.337
ENSG00000077585 E005 17.1493805 0.0264377920 9.550704e-01 0.9889416250 1 236168706 236168755 50 + 1.209 1.210 0.005
ENSG00000077585 E006 55.2333297 0.0004630416 3.677643e-01 0.6863468392 1 236178414 236178636 223 + 1.688 1.726 0.129
ENSG00000077585 E007 38.9976926 0.0004284854 5.190508e-01 0.7919048604 1 236179879 236180028 150 + 1.541 1.574 0.112
ENSG00000077585 E008 0.1145948 0.0112879100 1.000000e+00   1 236180029 236180188 160 + 0.056 0.000 -10.382
ENSG00000077585 E009 35.8656591 0.0004095504 7.720862e-01 0.9204905891 1 236183778 236183906 129 + 1.511 1.526 0.052
ENSG00000077585 E010 35.6102391 0.0005729085 2.808326e-01 0.6089283231 1 236205126 236205250 125 + 1.496 1.554 0.197
ENSG00000077585 E011 14.7986069 0.0011042214 8.469288e-01 0.9494860295 1 236208050 236208060 11 + 1.145 1.161 0.056
ENSG00000077585 E012 117.5985152 0.0002428524 1.523483e-01 0.4517434409 1 236208061 236208907 847 + 2.011 2.049 0.125
ENSG00000077585 E013 0.1308632 0.0122511951 1.415671e-01   1 236221791 236221865 75 + 0.000 0.157 12.339

Help

Please Click HERE to learn more details about the results from DEXseq.