ENSG00000078269

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355585 ENSG00000078269 No_inf pgwt_inf SYNJ2 protein_coding protein_coding 27.54589 10.71635 34.15755 0.2939766 0.6649752 1.671467 8.6701108 2.8786558 10.6986469 0.1304409 1.8467054 1.8903060 0.3043083 0.268500 0.311800 0.043300 0.9991665370 0.0001396648 FALSE TRUE
ENST00000367112 ENSG00000078269 No_inf pgwt_inf SYNJ2 protein_coding protein_coding_CDS_not_defined 27.54589 10.71635 34.15755 0.2939766 0.6649752 1.671467 0.6393808 0.8264559 0.4631828 0.3901600 0.2406000 -0.8218917 0.0365250 0.079600 0.013775 -0.065825 0.8708196314 0.0001396648 FALSE TRUE
ENST00000367113 ENSG00000078269 No_inf pgwt_inf SYNJ2 protein_coding protein_coding 27.54589 10.71635 34.15755 0.2939766 0.6649752 1.671467 3.6770012 2.4702122 3.2209566 0.4929008 2.1055485 0.3814978 0.1536250 0.229425 0.096775 -0.132650 0.9495999974 0.0001396648 FALSE FALSE
ENST00000367122 ENSG00000078269 No_inf pgwt_inf SYNJ2 protein_coding protein_coding 27.54589 10.71635 34.15755 0.2939766 0.6649752 1.671467 5.2588632 3.5901306 5.2239609 0.4814614 0.5564874 0.5398539 0.2227750 0.332425 0.153525 -0.178900 0.8145785030 0.0001396648 FALSE TRUE
MSTRG.25583.6 ENSG00000078269 No_inf pgwt_inf SYNJ2 protein_coding   27.54589 10.71635 34.15755 0.2939766 0.6649752 1.671467 8.0376866 0.0000000 12.5898906 0.0000000 2.4618328 10.2991955 0.2256167 0.000000 0.365575 0.365575 0.0001396648 0.0001396648 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000078269 E001 2.5961094 0.0094813508 6.249173e-01 8.498836e-01 6 157981863 157981953 91 + 0.548 0.479 -0.329
ENSG00000078269 E002 3.6245550 0.0040576132 1.414146e-01 4.348383e-01 6 157981954 157982037 84 + 0.687 0.479 -0.942
ENSG00000078269 E003 3.2023629 0.0046326353 8.667088e-01 9.575433e-01 6 157982038 157982088 51 + 0.600 0.582 -0.078
ENSG00000078269 E004 0.0000000       6 158017048 158017203 156 +      
ENSG00000078269 E005 6.4998092 0.0021417643 5.292338e-01 7.982425e-01 6 158017204 158017290 87 + 0.860 0.795 -0.256
ENSG00000078269 E006 0.0000000       6 158017465 158017795 331 +      
ENSG00000078269 E007 0.7026359 0.0137241411 5.604964e-01 8.163490e-01 6 158026985 158027075 91 + 0.242 0.147 -0.886
ENSG00000078269 E008 2.0699040 0.0071103051 1.776208e-02 1.345104e-01 6 158027076 158027165 90 + 0.548 0.147 -2.651
ENSG00000078269 E009 2.1084400 0.0236616110 3.088405e-01 6.351492e-01 6 158027367 158028755 1389 + 0.510 0.344 -0.886
ENSG00000078269 E010 32.6907245 0.0055573326 5.752544e-08 4.271043e-06 6 158028756 158029026 271 + 1.574 1.190 -1.331
ENSG00000078269 E011 1.3068575 0.0108267609 9.940236e-01 1.000000e+00 6 158029027 158029406 380 + 0.341 0.344 0.021
ENSG00000078269 E012 23.1087740 0.0007638885 3.725426e-05 1.300249e-03 6 158030408 158031000 593 + 1.415 1.117 -1.049
ENSG00000078269 E013 3.4133270 0.0297310402 4.539695e-01 7.505754e-01 6 158033455 158033489 35 + 0.646 0.534 -0.502
ENSG00000078269 E014 7.7649258 0.0049065446 5.547661e-01 8.136210e-01 6 158033490 158033680 191 + 0.886 0.957 0.266
ENSG00000078269 E015 3.8199864 0.0039273393 9.281472e-03 8.852250e-02 6 158043316 158043399 84 + 0.738 0.344 -1.886
ENSG00000078269 E016 3.5902230 0.0040114687 1.516807e-02 1.212302e-01 6 158054967 158055028 62 + 0.713 0.344 -1.786
ENSG00000078269 E017 4.2288898 0.0297163386 3.191331e-01 6.444056e-01 6 158059257 158059353 97 + 0.726 0.582 -0.614
ENSG00000078269 E018 0.2456901 0.0163539505 4.449381e-01   6 158059354 158059537 184 + 0.060 0.147 1.436
ENSG00000078269 E019 6.1248278 0.0036396013 3.071533e-01 6.335201e-01 6 158061992 158062054 63 + 0.851 0.735 -0.462
ENSG00000078269 E020 6.3535441 0.0021636718 2.359431e-01 5.610412e-01 6 158062055 158062164 110 + 0.869 0.735 -0.531
ENSG00000078269 E021 5.3558633 0.0074037018 2.188973e-02 1.523871e-01 6 158063791 158063872 82 + 0.842 0.534 -1.301
ENSG00000078269 E022 6.6475722 0.0097478644 2.055385e-02 1.466261e-01 6 158064601 158064750 150 + 0.919 0.626 -1.179
ENSG00000078269 E023 9.0396118 0.0017085958 9.611580e-01 9.907579e-01 6 158064826 158064991 166 + 0.963 0.976 0.047
ENSG00000078269 E024 8.8212021 0.0024950274 6.586569e-01 8.667588e-01 6 158066444 158066635 192 + 0.941 0.994 0.195
ENSG00000078269 E025 4.7538261 0.0030101064 9.867158e-01 9.996857e-01 6 158068647 158068728 82 + 0.726 0.735 0.038
ENSG00000078269 E026 6.8433819 0.0033845688 3.925651e-01 7.058768e-01 6 158069533 158069673 141 + 0.886 0.795 -0.355
ENSG00000078269 E027 0.2454678 0.0165091061 4.456236e-01   6 158070128 158070506 379 + 0.060 0.147 1.436
ENSG00000078269 E028 7.8538793 0.0017554239 7.041042e-02 3.009810e-01 6 158071602 158071794 193 + 0.963 0.766 -0.760
ENSG00000078269 E029 11.1213154 0.0012174926 5.209480e-01 7.930899e-01 6 158074580 158074738 159 + 1.063 1.011 -0.190
ENSG00000078269 E030 7.4462335 0.0269568585 5.764194e-01 8.250469e-01 6 158076626 158076782 157 + 0.911 0.848 -0.242
ENSG00000078269 E031 0.8858131 0.1419777081 3.019171e-02 1.851690e-01 6 158077680 158078163 484 + 0.113 0.479 2.758
ENSG00000078269 E032 6.6810558 0.0171864215 1.113460e-01 3.855768e-01 6 158078164 158078281 118 + 0.903 0.701 -0.797
ENSG00000078269 E033 1.0963634 0.0164010580 2.810605e-01 6.090307e-01 6 158078282 158079356 1075 + 0.242 0.417 1.114
ENSG00000078269 E034 13.3032664 0.0204197403 2.342340e-01 5.596608e-01 6 158081109 158081327 219 + 1.080 1.201 0.436
ENSG00000078269 E035 5.7210329 0.0103071114 7.892686e-01 9.270562e-01 6 158081432 158081510 79 + 0.783 0.822 0.156
ENSG00000078269 E036 8.8578044 0.0177501051 3.852698e-01 7.002578e-01 6 158083429 158083597 169 + 0.926 1.028 0.377
ENSG00000078269 E037 13.7247311 0.0044637755 4.818305e-01 7.691379e-01 6 158084001 158084174 174 + 1.111 1.179 0.244
ENSG00000078269 E038 10.0594939 0.0014850446 5.758875e-01 8.248124e-01 6 158086855 158086989 135 + 1.022 0.976 -0.171
ENSG00000078269 E039 8.7462798 0.0016124967 3.043450e-01 6.311116e-01 6 158088660 158088772 113 + 0.919 1.028 0.406
ENSG00000078269 E040 9.3555668 0.0027718139 2.544209e-01 5.814161e-01 6 158089839 158089947 109 + 0.941 1.060 0.436
ENSG00000078269 E041 12.4254629 0.0164898888 4.795068e-01 7.672684e-01 6 158092926 158093104 179 + 1.069 1.143 0.266
ENSG00000078269 E042 1.0603319 0.2313626397 8.483119e-01 9.501938e-01 6 158093888 158094094 207 + 0.310 0.257 -0.370
ENSG00000078269 E043 300.1530350 0.0010537726 3.616222e-09 3.379767e-07 6 158095618 158099181 3564 + 2.410 2.504 0.313

Help

Please Click HERE to learn more details about the results from DEXseq.