ENSG00000080189

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000243896 ENSG00000080189 No_inf pgwt_inf SLC35C2 protein_coding protein_coding 48.52508 43.57685 53.8327 3.124135 4.145893 0.3048579 3.959101 0.000000 5.688214 0.0000000 1.623299 9.15436605 0.07834167 0.000000 0.104325 0.104325 0.0005112954 0.0005112954 FALSE TRUE
ENST00000317734 ENSG00000080189 No_inf pgwt_inf SLC35C2 protein_coding protein_coding 48.52508 43.57685 53.8327 3.124135 4.145893 0.3048579 10.925011 8.582095 12.969735 0.9120067 1.968057 0.59517898 0.22628333 0.198000 0.244600 0.046600 0.9928472467 0.0005112954 FALSE TRUE
ENST00000372227 ENSG00000080189 No_inf pgwt_inf SLC35C2 protein_coding protein_coding 48.52508 43.57685 53.8327 3.124135 4.145893 0.3048579 2.035285 3.792534 1.606593 1.2860025 1.011154 -1.23400489 0.04352500 0.086200 0.029000 -0.057200 0.9928472467 0.0005112954 FALSE TRUE
ENST00000480329 ENSG00000080189 No_inf pgwt_inf SLC35C2 protein_coding protein_coding_CDS_not_defined 48.52508 43.57685 53.8327 3.124135 4.145893 0.3048579 4.470315 6.842637 3.306529 1.5506721 2.398877 -1.04698484 0.09299167 0.157450 0.055625 -0.101825 0.8996108696 0.0005112954 FALSE TRUE
ENST00000484318 ENSG00000080189 No_inf pgwt_inf SLC35C2 protein_coding protein_coding_CDS_not_defined 48.52508 43.57685 53.8327 3.124135 4.145893 0.3048579 2.776173 0.000000 4.465503 0.0000000 2.591636 8.80590604 0.04937500 0.000000 0.073650 0.073650 0.9796447859 0.0005112954 FALSE FALSE
ENST00000487729 ENSG00000080189 No_inf pgwt_inf SLC35C2 protein_coding protein_coding_CDS_not_defined 48.52508 43.57685 53.8327 3.124135 4.145893 0.3048579 12.084523 12.002820 14.474852 2.8456171 1.349617 0.26997010 0.24661667 0.267975 0.268450 0.000475 1.0000000000 0.0005112954 FALSE TRUE
MSTRG.18356.3 ENSG00000080189 No_inf pgwt_inf SLC35C2 protein_coding   48.52508 43.57685 53.8327 3.124135 4.145893 0.3048579 4.727378 4.632840 4.462862 1.8052266 2.719613 -0.05380911 0.10533333 0.115000 0.093825 -0.021175 0.9928472467 0.0005112954 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000080189 E001 0.000000       20 46345980 46345983 4 -      
ENSG00000080189 E002 15.681165 0.0075418882 0.0030907158 0.04162195 20 46345984 46349527 3544 - 1.088 1.327 0.848
ENSG00000080189 E003 0.507763 0.0341041573 0.2510397873   20 46349528 46349529 2 - 0.088 0.255 1.828
ENSG00000080189 E004 85.711117 0.0054943371 0.5574639988 0.81506924 20 46349530 46350354 825 - 1.924 1.952 0.092
ENSG00000080189 E005 46.650155 0.0051376335 0.1453534023 0.44105348 20 46350355 46350524 170 - 1.639 1.715 0.260
ENSG00000080189 E006 8.909881 0.0017592636 0.0006558632 0.01296728 20 46350525 46350760 236 - 0.806 1.131 1.214
ENSG00000080189 E007 15.486452 0.0009085266 0.0151441448 0.12113034 20 46350761 46350770 10 - 1.119 1.299 0.639
ENSG00000080189 E008 44.683257 0.0003168837 0.3683392454 0.68681620 20 46350771 46350890 120 - 1.639 1.680 0.142
ENSG00000080189 E009 39.419020 0.0003722291 0.9372886070 0.98310665 20 46352051 46352122 72 - 1.604 1.610 0.021
ENSG00000080189 E010 26.209792 0.0005072783 0.4286355864 0.73238755 20 46352123 46352149 27 - 1.411 1.458 0.164
ENSG00000080189 E011 20.953076 0.0006775986 0.7627839794 0.91576169 20 46352150 46352163 14 - 1.350 1.333 -0.059
ENSG00000080189 E012 22.955778 0.0042107339 0.9250753231 0.97892703 20 46352164 46352185 22 - 1.375 1.384 0.029
ENSG00000080189 E013 29.186007 0.0015269855 0.8692562903 0.95855426 20 46352186 46352226 41 - 1.474 1.485 0.039
ENSG00000080189 E014 7.144505 0.0086504076 0.0062590608 0.06793670 20 46352227 46353197 971 - 0.740 1.036 1.132
ENSG00000080189 E015 47.270584 0.0019792922 0.2608480083 0.58844881 20 46354882 46354965 84 - 1.707 1.658 -0.166
ENSG00000080189 E016 29.728237 0.0011681848 0.6989129460 0.88599613 20 46355073 46355103 31 - 1.496 1.478 -0.064
ENSG00000080189 E017 38.478678 0.0003623987 0.7854454803 0.92561174 20 46355104 46355178 75 - 1.589 1.604 0.052
ENSG00000080189 E018 24.423503 0.0005931758 0.8679136703 0.95806495 20 46355179 46355241 63 - 1.399 1.411 0.042
ENSG00000080189 E019 3.094688 0.1513234471 0.3976969505 0.70991426 20 46355242 46355279 38 - 0.541 0.675 0.592
ENSG00000080189 E020 25.471477 0.0012246766 0.7895481562 0.92718092 20 46355802 46355874 73 - 1.429 1.416 -0.046
ENSG00000080189 E021 23.308463 0.0058423811 0.3500326994 0.67058231 20 46356574 46356637 64 - 1.414 1.354 -0.210
ENSG00000080189 E022 23.547435 0.0005863928 0.0350339405 0.20204365 20 46357623 46357702 80 - 1.447 1.322 -0.434
ENSG00000080189 E023 20.643271 0.0006494132 0.3493502185 0.67000817 20 46357703 46357773 71 - 1.363 1.305 -0.200
ENSG00000080189 E024 18.479205 0.0007655914 0.0665464287 0.29195733 20 46358387 46358426 40 - 1.345 1.223 -0.427
ENSG00000080189 E025 30.154614 0.0004886034 0.0074671551 0.07665856 20 46358427 46358558 132 - 1.557 1.416 -0.486
ENSG00000080189 E026 21.956186 0.0022878628 0.0342917614 0.19943715 20 46358559 46358690 132 - 1.422 1.288 -0.467
ENSG00000080189 E027 16.171587 0.0015972519 0.5969385507 0.83596908 20 46358691 46358763 73 - 1.252 1.216 -0.126
ENSG00000080189 E028 9.370463 0.0014985172 0.7591487071 0.91451551 20 46358764 46358958 195 - 1.028 1.003 -0.094
ENSG00000080189 E029 2.796477 0.0052305073 0.8173966266 0.93746052 20 46358959 46359082 124 - 0.594 0.564 -0.134
ENSG00000080189 E030 1.356520 0.0440969810 0.5850143057 0.82963951 20 46363086 46363174 89 - 0.327 0.415 0.508
ENSG00000080189 E031 2.173323 0.0065543210 0.5522486159 0.81211862 20 46364040 46364370 331 - 0.541 0.457 -0.408
ENSG00000080189 E032 8.986350 0.0015696108 0.0279833360 0.17703770 20 46364371 46364458 88 - 1.088 0.884 -0.756

Help

Please Click HERE to learn more details about the results from DEXseq.