ENSG00000084234

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000338167 ENSG00000084234 No_inf pgwt_inf APLP2 protein_coding protein_coding 456.3595 603.7971 374.4518 2.092432 1.61851 -0.689269 237.90473 284.17270 209.987071 7.763791 4.320845 -0.4364495 0.5311750 0.470575 0.560925 0.090350 0.9928472 0.0101036 FALSE TRUE
ENST00000345598 ENSG00000084234 No_inf pgwt_inf APLP2 protein_coding protein_coding 456.3595 603.7971 374.4518 2.092432 1.61851 -0.689269 30.63515 79.59967 1.538425 1.767826 1.538425 -5.6840698 0.0544750 0.131850 0.004125 -0.127725 0.0101036 0.0101036 FALSE TRUE
ENST00000528499 ENSG00000084234 No_inf pgwt_inf APLP2 protein_coding protein_coding 456.3595 603.7971 374.4518 2.092432 1.61851 -0.689269 92.63399 98.34938 90.795326 4.153527 5.818716 -0.1152858 0.2107250 0.162950 0.242475 0.079525 0.9928472 0.0101036 FALSE TRUE
ENST00000533616 ENSG00000084234 No_inf pgwt_inf APLP2 protein_coding nonsense_mediated_decay 456.3595 603.7971 374.4518 2.092432 1.61851 -0.689269 65.79191 107.83432 38.014754 4.087440 3.570611 -1.5039394 0.1372833 0.178575 0.101425 -0.077150 0.9548687 0.0101036 FALSE TRUE
ENST00000650012 ENSG00000084234 No_inf pgwt_inf APLP2 protein_coding protein_coding 456.3595 603.7971 374.4518 2.092432 1.61851 -0.689269 17.26046 10.18650 26.887428 1.493617 1.619506 1.3993937 0.0421500 0.016900 0.071775 0.054875 0.1337390 0.0101036 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000084234 E001 0.1315150 1.233902e-02 8.375292e-01   11 130068147 130068158 12 + 0.000 0.079 9.740
ENSG00000084234 E002 0.0000000       11 130069837 130069860 24 +      
ENSG00000084234 E003 0.1141751 1.123788e-02 3.465511e-01   11 130069861 130069862 2 + 0.114 0.000 -13.022
ENSG00000084234 E004 2.1565002 6.928136e-03 2.223275e-02 1.540995e-01 11 130069863 130069890 28 + 0.662 0.343 -1.578
ENSG00000084234 E005 2.2710950 6.320379e-03 1.225043e-02 1.059163e-01 11 130069891 130069893 3 + 0.689 0.343 -1.693
ENSG00000084234 E006 2.2710950 6.320379e-03 1.225043e-02 1.059163e-01 11 130069894 130069895 2 + 0.689 0.343 -1.693
ENSG00000084234 E007 2.6311550 5.582953e-03 7.541958e-03 7.718502e-02 11 130069896 130069898 3 + 0.739 0.381 -1.677
ENSG00000084234 E008 7.0171953 2.194447e-03 1.673395e-03 2.655721e-02 11 130069899 130069905 7 + 1.060 0.749 -1.184
ENSG00000084234 E009 50.9106830 7.207518e-03 5.428509e-01 8.068592e-01 11 130069906 130069915 10 + 1.715 1.691 -0.080
ENSG00000084234 E010 184.0998931 9.254069e-04 7.108978e-02 3.025633e-01 11 130069916 130070014 99 + 2.275 2.238 -0.123
ENSG00000084234 E011 49.4618497 3.189829e-04 1.842906e-01 4.975888e-01 11 130070015 130070018 4 + 1.717 1.669 -0.163
ENSG00000084234 E012 67.3323448 1.024057e-03 5.000715e-02 2.478230e-01 11 130070019 130070037 19 + 1.860 1.793 -0.226
ENSG00000084234 E013 120.3866601 3.764565e-04 2.003566e-04 5.123377e-03 11 130070038 130070082 45 + 2.127 2.030 -0.326
ENSG00000084234 E014 0.0000000       11 130070568 130070747 180 +      
ENSG00000084234 E015 0.1315150 1.233902e-02 8.375292e-01   11 130100270 130100425 156 + 0.000 0.079 11.605
ENSG00000084234 E016 0.1138060 1.120427e-02 3.465597e-01   11 130101370 130101513 144 + 0.114 0.000 -13.023
ENSG00000084234 E017 0.0000000       11 130101926 130102000 75 +      
ENSG00000084234 E018 0.7032024 3.573556e-02 3.214154e-02 1.916507e-01 11 130108605 130108983 379 + 0.397 0.079 -2.900
ENSG00000084234 E019 0.4912017 1.018823e-01 6.932326e-01   11 130109161 130109426 266 + 0.204 0.146 -0.578
ENSG00000084234 E020 0.3600528 2.199267e-01 4.092080e-01   11 130109427 130109428 2 + 0.204 0.079 -1.579
ENSG00000084234 E021 296.7732150 8.421694e-05 1.426577e-10 1.635664e-08 11 130109429 130109549 121 + 2.522 2.416 -0.351
ENSG00000084234 E022 146.8448618 2.133770e-03 3.667849e-03 4.681688e-02 11 130109550 130109581 32 + 2.204 2.122 -0.276
ENSG00000084234 E023 122.3391152 2.459401e-03 5.790502e-03 6.420104e-02 11 130109582 130109602 21 + 2.127 2.042 -0.286
ENSG00000084234 E024 0.0000000       11 130109603 130109617 15 +      
ENSG00000084234 E025 0.0000000       11 130109618 130109823 206 +      
ENSG00000084234 E026 134.7490655 1.366794e-04 1.470723e-04 4.014128e-03 11 130110538 130110564 27 + 2.173 2.081 -0.305
ENSG00000084234 E027 109.8290374 2.960424e-04 5.483211e-03 6.181392e-02 11 130110565 130110573 9 + 2.074 2.001 -0.245
ENSG00000084234 E028 115.1328923 1.589597e-04 3.226755e-03 4.282389e-02 11 130110574 130110585 12 + 2.095 2.020 -0.251
ENSG00000084234 E029 219.9090668 8.631776e-05 2.191353e-03 3.252171e-02 11 130110586 130110661 76 + 2.362 2.308 -0.180
ENSG00000084234 E030 220.0714930 8.385453e-05 2.407716e-04 5.964348e-03 11 130120706 130120765 60 + 2.370 2.303 -0.222
ENSG00000084234 E031 206.8790100 8.172945e-05 7.673393e-03 7.799152e-02 11 130120766 130120818 53 + 2.332 2.284 -0.158
ENSG00000084234 E032 0.3940400 1.593835e-02 2.145857e-01   11 130120819 130120823 5 + 0.000 0.204 13.095
ENSG00000084234 E033 274.5627698 6.706751e-05 6.418134e-03 6.897945e-02 11 130121614 130121712 99 + 2.450 2.409 -0.137
ENSG00000084234 E034 162.7561495 9.632037e-05 2.011988e-02 1.446953e-01 11 130121713 130121745 33 + 2.227 2.181 -0.155
ENSG00000084234 E035 289.0134867 6.966770e-05 8.777465e-02 3.399931e-01 11 130121746 130121810 65 + 2.460 2.439 -0.071
ENSG00000084234 E036 650.1070490 5.023062e-05 1.773022e-02 1.344028e-01 11 130122305 130122513 209 + 2.810 2.791 -0.063
ENSG00000084234 E037 369.7812718 5.433340e-05 1.157653e-06 6.448602e-05 11 130123612 130123779 168 + 2.595 2.527 -0.227
ENSG00000084234 E038 539.8611469 4.389002e-05 1.230517e-04 3.487626e-03 11 130126700 130126830 131 + 2.743 2.702 -0.136
ENSG00000084234 E039 335.8922796 5.324859e-05 1.855616e-05 7.232545e-04 11 130127766 130127840 75 + 2.550 2.488 -0.207
ENSG00000084234 E040 584.3688162 4.807574e-05 3.513642e-02 2.023928e-01 11 130129048 130129206 159 + 2.762 2.745 -0.056
ENSG00000084234 E041 558.3398821 3.682445e-05 1.356828e-01 4.267805e-01 11 130130038 130130166 129 + 2.738 2.729 -0.031
ENSG00000084234 E042 484.4804307 2.686956e-04 2.782805e-01 6.062624e-01 11 130133629 130133728 100 + 2.675 2.668 -0.022
ENSG00000084234 E043 518.6778915 4.628567e-05 3.735167e-01 6.912319e-01 11 130135563 130135715 153 + 2.686 2.708 0.075
ENSG00000084234 E044 50.9210882 2.648707e-04 2.879563e-02 1.794606e-01 11 130137256 130137291 36 + 1.629 1.736 0.364
ENSG00000084234 E045 14.4081456 2.928335e-03 1.404463e-04 3.864737e-03 11 130138778 130139655 878 + 0.928 1.270 1.238
ENSG00000084234 E046 433.4406908 4.904434e-05 9.518983e-01 9.880919e-01 11 130140398 130140483 86 + 2.615 2.626 0.037
ENSG00000084234 E047 31.1271777 4.644277e-04 4.419170e-09 4.030860e-07 11 130140495 130141411 917 + 1.227 1.594 1.272
ENSG00000084234 E048 10.1242326 1.546920e-02 4.603499e-02 2.360032e-01 11 130141412 130141497 86 + 0.880 1.101 0.821
ENSG00000084234 E049 563.4556355 7.608248e-04 6.762881e-01 8.753031e-01 11 130141498 130141572 75 + 2.725 2.742 0.058
ENSG00000084234 E050 5.5557968 3.239120e-02 2.453450e-01 5.718131e-01 11 130141573 130141918 346 + 0.689 0.858 0.676
ENSG00000084234 E051 808.4313242 4.546548e-04 8.772480e-01 9.612481e-01 11 130141919 130142074 156 + 2.887 2.895 0.027
ENSG00000084234 E052 4284.9987143 1.584555e-04 2.494263e-44 4.565878e-41 11 130143347 130144858 1512 + 3.560 3.646 0.288

Help

Please Click HERE to learn more details about the results from DEXseq.