ENSG00000085382

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262903 ENSG00000085382 No_inf pgwt_inf HACE1 protein_coding protein_coding 9.433503 7.129082 8.178475 0.7663567 3.587433 0.1978563 2.1327535 1.7688977 2.8015481 0.06893517 0.16006697 0.6603812 0.31379167 0.258400 0.476600 0.218200 0.992847247 0.000768277 FALSE TRUE
ENST00000369125 ENSG00000085382 No_inf pgwt_inf HACE1 protein_coding protein_coding 9.433503 7.129082 8.178475 0.7663567 3.587433 0.1978563 0.6011356 0.0000000 0.1711945 0.00000000 0.17119455 4.1794676 0.08705833 0.000000 0.040275 0.040275 0.992847247 0.000768277 FALSE TRUE
ENST00000369127 ENSG00000085382 No_inf pgwt_inf HACE1 protein_coding retained_intron 9.433503 7.129082 8.178475 0.7663567 3.587433 0.1978563 0.6623396 0.9684341 0.5501389 0.18009149 0.08536275 -0.8046902 0.09317500 0.134725 0.092375 -0.042350 0.992847247 0.000768277 FALSE TRUE
ENST00000517424 ENSG00000085382 No_inf pgwt_inf HACE1 protein_coding nonsense_mediated_decay 9.433503 7.129082 8.178475 0.7663567 3.587433 0.1978563 0.9679770 0.3671968 0.6174086 0.36719678 0.35822939 0.7340879 0.13340833 0.061625 0.129450 0.067825 0.992847247 0.000768277 FALSE TRUE
ENST00000517995 ENSG00000085382 No_inf pgwt_inf HACE1 protein_coding protein_coding_CDS_not_defined 9.433503 7.129082 8.178475 0.7663567 3.587433 0.1978563 1.1537988 2.9126785 0.0000000 0.47744559 0.00000000 -8.1911473 0.15790833 0.416625 0.000000 -0.416625 0.000768277 0.000768277 FALSE TRUE
ENST00000518402 ENSG00000085382 No_inf pgwt_inf HACE1 protein_coding protein_coding 9.433503 7.129082 8.178475 0.7663567 3.587433 0.1978563 0.5279722 0.8542479 0.0000000 0.85424793 0.00000000 -6.4333733 0.04789167 0.092000 0.000000 -0.092000 0.992847247 0.000768277 FALSE TRUE
MSTRG.25060.12 ENSG00000085382 No_inf pgwt_inf HACE1 protein_coding   9.433503 7.129082 8.178475 0.7663567 3.587433 0.1978563 3.1706175 0.0000000 3.7528834 0.00000000 3.75288342 8.5556948 0.12804167 0.000000 0.198275 0.198275 0.992847247 0.000768277   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000085382 E001 0.0000000       6 104728094 104728094 1 -      
ENSG00000085382 E002 0.0000000       6 104728095 104728096 2 -      
ENSG00000085382 E003 17.0379634 0.001006340 0.013252047 0.11140114 6 104728097 104728921 825 - 1.146 1.312 0.586
ENSG00000085382 E004 4.7674001 0.003269677 0.161616069 0.46492177 6 104728922 104729041 120 - 0.655 0.815 0.654
ENSG00000085382 E005 5.9117407 0.002580458 0.058460723 0.27137513 6 104729042 104729169 128 - 0.704 0.908 0.804
ENSG00000085382 E006 9.7939843 0.001766878 0.027953393 0.17689043 6 104729170 104729317 148 - 0.905 1.098 0.711
ENSG00000085382 E007 18.3262674 0.006041035 0.120722037 0.40202309 6 104729318 104729764 447 - 1.216 1.321 0.370
ENSG00000085382 E008 8.2451883 0.004334687 0.703010102 0.88865110 6 104730303 104730416 114 - 0.985 0.942 -0.160
ENSG00000085382 E009 0.9807818 0.013228060 0.798132639 0.93058795 6 104730417 104732370 1954 - 0.319 0.276 -0.289
ENSG00000085382 E010 3.1102916 0.172792449 0.605116382 0.83982244 6 104744160 104744173 14 - 0.569 0.636 0.296
ENSG00000085382 E011 4.5834500 0.064243475 0.813853547 0.93664696 6 104744174 104744230 57 - 0.727 0.752 0.104
ENSG00000085382 E012 4.8136416 0.014741625 0.911217039 0.97370539 6 104744512 104744610 99 - 0.769 0.752 -0.066
ENSG00000085382 E013 6.3208900 0.002380886 0.746155483 0.90901687 6 104750341 104750472 132 - 0.842 0.871 0.110
ENSG00000085382 E014 9.9874437 0.001447766 0.146077572 0.44198733 6 104771193 104771389 197 - 0.960 1.082 0.448
ENSG00000085382 E015 6.6161189 0.002708238 0.258003596 0.58589901 6 104771925 104772074 150 - 0.807 0.920 0.434
ENSG00000085382 E016 3.6853669 0.036098301 0.634057929 0.85417101 6 104776741 104776828 88 - 0.704 0.636 -0.289
ENSG00000085382 E017 3.4698380 0.032116049 0.797215369 0.93017398 6 104777013 104777097 85 - 0.628 0.657 0.126
ENSG00000085382 E018 1.9794834 0.049125656 0.886594765 0.96454874 6 104777098 104777110 13 - 0.462 0.476 0.074
ENSG00000085382 E019 3.5941672 0.025695915 0.029482412 0.18232797 6 104777206 104777317 112 - 0.807 0.507 -1.289
ENSG00000085382 E020 0.1139502 0.011379883 0.446422688   6 104780353 104780457 105 - 0.104 0.000 -11.441
ENSG00000085382 E021 0.0000000       6 104782363 104782455 93 -      
ENSG00000085382 E022 1.7175069 0.040342478 0.739103632 0.90562247 6 104784086 104784129 44 - 0.462 0.407 -0.289
ENSG00000085382 E023 2.7332627 0.017440207 0.684558165 0.87970829 6 104784130 104784173 44 - 0.536 0.589 0.242
ENSG00000085382 E024 3.3733618 0.004544820 0.382785089 0.69881103 6 104784417 104784485 69 - 0.569 0.678 0.477
ENSG00000085382 E025 10.4703426 0.001383514 0.048053810 0.24189052 6 104784985 104785319 335 - 1.146 0.974 -0.626
ENSG00000085382 E026 7.7301284 0.001876491 0.283767923 0.61146983 6 104785320 104787414 2095 - 0.875 0.974 0.374
ENSG00000085382 E027 3.5957454 0.005071431 0.019586920 0.14218395 6 104791504 104791654 151 - 0.807 0.507 -1.289
ENSG00000085382 E028 2.7449344 0.042194326 0.033914489 0.19814515 6 104795579 104795685 107 - 0.727 0.407 -1.482
ENSG00000085382 E029 1.7979758 0.093670235 0.159264185 0.46187919 6 104796655 104796716 62 - 0.569 0.324 -1.289
ENSG00000085382 E030 1.2901116 0.127050795 0.031720559 0.19051221 6 104796717 104796756 40 - 0.536 0.159 -2.460
ENSG00000085382 E031 2.5181133 0.097202490 0.134470081 0.42500160 6 104796929 104797025 97 - 0.680 0.407 -1.289
ENSG00000085382 E032 1.5869901 0.011294126 0.550088044 0.81082810 6 104811311 104811393 83 - 0.462 0.367 -0.511
ENSG00000085382 E033 0.0000000       6 104824814 104824907 94 -      
ENSG00000085382 E034 0.3417870 0.020763902 0.072907574   6 104833042 104833059 18 - 0.258 0.000 -12.867
ENSG00000085382 E035 1.1743055 0.016934490 0.027815156 0.17641953 6 104833060 104833147 88 - 0.500 0.159 -2.289
ENSG00000085382 E036 0.7191322 0.016747535 0.300870711 0.62817677 6 104833148 104833173 26 - 0.319 0.159 -1.289
ENSG00000085382 E037 0.9637179 0.014082297 0.338915367 0.66128192 6 104843223 104843298 76 - 0.372 0.221 -1.026
ENSG00000085382 E038 2.3522235 0.006075287 0.001596171 0.02561892 6 104849142 104849246 105 - 0.727 0.276 -2.289
ENSG00000085382 E039 1.6680242 0.010884475 0.051790974 0.25300227 6 104850907 104850996 90 - 0.569 0.276 -1.611
ENSG00000085382 E040 0.9995100 0.013789136 0.654936220 0.86549757 6 104852317 104852371 55 - 0.258 0.324 0.448
ENSG00000085382 E041 0.2628107 0.016305113 0.312052142   6 104858394 104858532 139 - 0.000 0.159 11.208
ENSG00000085382 E042 0.0000000       6 104859379 104859436 58 -      
ENSG00000085382 E043 0.0000000       6 104859437 104859566 130 -      
ENSG00000085382 E044 1.9112604 0.007238533 0.061716211 0.27978367 6 104859567 104859919 353 - 0.600 0.324 -1.426

Help

Please Click HERE to learn more details about the results from DEXseq.