ENSG00000087053

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000352297 ENSG00000087053 No_inf pgwt_inf MTMR2 protein_coding protein_coding 14.26054 9.524471 16.27393 0.3913452 0.4827667 0.7722238 7.8877076 5.4168041 7.8633456 0.6051609 0.8670027 0.536874 0.55682500 0.577925 0.480875 -0.097050 0.99284725 0.01224948 FALSE TRUE
ENST00000409459 ENSG00000087053 No_inf pgwt_inf MTMR2 protein_coding protein_coding 14.26054 9.524471 16.27393 0.3913452 0.4827667 0.7722238 1.3772294 0.0000000 2.3668804 0.0000000 0.1932485 7.892926 0.08334167 0.000000 0.146600 0.146600 0.01224948 0.01224948 FALSE TRUE
ENST00000675362 ENSG00000087053 No_inf pgwt_inf MTMR2 protein_coding protein_coding 14.26054 9.524471 16.27393 0.3913452 0.4827667 0.7722238 0.1875810 0.5627429 0.0000000 0.5627429 0.0000000 -5.839816 0.01766667 0.053000 0.000000 -0.053000 0.99284725 0.01224948 FALSE TRUE
ENST00000675438 ENSG00000087053 No_inf pgwt_inf MTMR2 protein_coding protein_coding 14.26054 9.524471 16.27393 0.3913452 0.4827667 0.7722238 0.8067460 1.3004050 0.5981794 0.8053011 0.5981794 -1.107444 0.06515000 0.127625 0.037425 -0.090200 0.99284725 0.01224948 FALSE TRUE
ENST00000675454 ENSG00000087053 No_inf pgwt_inf MTMR2 protein_coding protein_coding 14.26054 9.524471 16.27393 0.3913452 0.4827667 0.7722238 0.1669369 0.5008108 0.0000000 0.5008108 0.0000000 -5.674717 0.01895000 0.056850 0.000000 -0.056850 0.99284725 0.01224948 FALSE TRUE
ENST00000676261 ENSG00000087053 No_inf pgwt_inf MTMR2 protein_coding protein_coding 14.26054 9.524471 16.27393 0.3913452 0.4827667 0.7722238 1.0090740 0.0000000 1.9600279 0.0000000 0.6577863 7.622072 0.06227500 0.000000 0.124075 0.124075 0.41730368 0.01224948 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000087053 E001 3.2915100 0.1499032230 0.3624736691 0.681850137 11 95821766 95824066 2301 - 0.570 0.697 0.551
ENSG00000087053 E002 0.5880411 0.0144728859 0.4705210212   11 95830548 95831161 614 - 0.236 0.124 -1.126
ENSG00000087053 E003 0.1315150 0.0122170618 0.2836804790   11 95832880 95832881 2 - 0.000 0.124 12.987
ENSG00000087053 E004 14.1805390 0.0010838417 0.2033721030 0.522414181 11 95832882 95834087 1206 - 1.130 1.228 0.350
ENSG00000087053 E005 1.2266721 0.0109896601 0.3507338506 0.671102119 11 95834088 95834088 1 - 0.280 0.424 0.874
ENSG00000087053 E006 1.1127219 0.0114077317 0.2233662250 0.547447681 11 95834089 95834091 3 - 0.236 0.424 1.196
ENSG00000087053 E007 1.1133665 0.0143008175 0.2243211369 0.548466833 11 95834092 95834102 11 - 0.236 0.424 1.196
ENSG00000087053 E008 83.6542862 0.0002461255 0.0001603502 0.004294828 11 95834103 95835289 1187 - 1.870 1.981 0.375
ENSG00000087053 E009 9.7080580 0.0014940194 0.6957337284 0.884266863 11 95835290 95835320 31 - 1.032 0.998 -0.126
ENSG00000087053 E010 17.8679746 0.0008086327 0.6338105690 0.854123013 11 95835321 95835451 131 - 1.277 1.245 -0.112
ENSG00000087053 E011 17.8269833 0.0093264710 0.0601140501 0.275735924 11 95836148 95836324 177 - 1.316 1.164 -0.537
ENSG00000087053 E012 14.6779631 0.0190904900 0.9041402955 0.971687315 11 95838094 95838207 114 - 1.179 1.193 0.048
ENSG00000087053 E013 14.2595426 0.0011094618 0.4138966276 0.721456023 11 95841617 95841709 93 - 1.147 1.211 0.227
ENSG00000087053 E014 21.9644174 0.0020225502 0.4763529002 0.765562220 11 95844953 95845159 207 - 1.331 1.378 0.162
ENSG00000087053 E015 19.4152681 0.0007760143 0.5748911433 0.824447924 11 95847714 95847899 186 - 1.312 1.276 -0.126
ENSG00000087053 E016 17.9420872 0.0008755743 0.3729604617 0.690859152 11 95849674 95849862 189 - 1.289 1.228 -0.214
ENSG00000087053 E017 0.2450991 0.0161397833 0.6390808226   11 95850208 95850599 392 - 0.072 0.124 0.874
ENSG00000087053 E018 11.9416027 0.0011897320 0.0111706251 0.099950077 11 95850600 95850749 150 - 1.174 0.952 -0.808
ENSG00000087053 E019 4.0188273 0.0036110101 0.1376451848 0.429699046 11 95857552 95857555 4 - 0.756 0.562 -0.827
ENSG00000087053 E020 7.4376995 0.0019242303 0.8018614261 0.932130765 11 95857556 95857635 80 - 0.925 0.901 -0.091
ENSG00000087053 E021 1.0971864 0.0117844064 0.5794479161 0.826226873 11 95857636 95858530 895 - 0.280 0.367 0.552
ENSG00000087053 E022 9.2189869 0.0014489879 0.5884761586 0.831776063 11 95858531 95858632 102 - 1.017 0.968 -0.183
ENSG00000087053 E023 9.2987834 0.0034353413 0.2752562873 0.603313595 11 95861992 95862102 111 - 1.039 0.936 -0.384
ENSG00000087053 E024 7.8242821 0.0091108557 0.1080583181 0.379566193 11 95862272 95862366 95 - 0.994 0.822 -0.654
ENSG00000087053 E025 1.7642628 0.0075948457 0.1958986423 0.512642972 11 95862367 95865439 3073 - 0.501 0.300 -1.126
ENSG00000087053 E026 0.1139502 0.0111197069 1.0000000000   11 95865440 95865590 151 - 0.072 0.000 -12.715
ENSG00000087053 E027 0.0000000       11 95865591 95865600 10 -      
ENSG00000087053 E028 7.0060779 0.0021874296 0.1754888758 0.486069209 11 95865601 95865676 76 - 0.943 0.800 -0.553
ENSG00000087053 E029 0.0000000       11 95866384 95866402 19 -      
ENSG00000087053 E030 0.2284008 0.0153210556 0.5298758426   11 95866403 95866486 84 - 0.134 0.000 -13.625
ENSG00000087053 E031 1.2711076 0.0112352041 0.0454768928 0.234409781 11 95882374 95882496 123 - 0.448 0.124 -2.448
ENSG00000087053 E032 0.0000000       11 95887326 95887373 48 -      
ENSG00000087053 E033 0.0000000       11 95887610 95887611 2 -      
ENSG00000087053 E034 1.8930918 0.0079550977 0.3758299929 0.693403921 11 95887612 95887684 73 - 0.501 0.367 -0.711
ENSG00000087053 E035 0.1316618 0.0122467812 0.2836568043   11 95887685 95887759 75 - 0.000 0.124 12.987
ENSG00000087053 E036 5.4878918 0.0053591950 0.4847961576 0.771043466 11 95888156 95888261 106 - 0.832 0.751 -0.319
ENSG00000087053 E037 0.1138060 0.0111125601 1.0000000000   11 95907862 95907923 62 - 0.072 0.000 -12.715
ENSG00000087053 E038 0.0000000       11 95910610 95910843 234 -      
ENSG00000087053 E039 0.0000000       11 95912939 95913077 139 -      
ENSG00000087053 E040 2.7301761 0.0607339591 0.4313757026 0.734115873 11 95914242 95914312 71 - 0.610 0.475 -0.629
ENSG00000087053 E041 0.1308632 0.0121795559 0.2837570752   11 95914313 95914333 21 - 0.000 0.124 12.987
ENSG00000087053 E042 0.1316618 0.0122467812 0.2836568043   11 95915815 95915963 149 - 0.000 0.124 12.987
ENSG00000087053 E043 0.0000000       11 95917377 95917486 110 -      
ENSG00000087053 E044 0.0000000       11 95923621 95923691 71 -      
ENSG00000087053 E045 0.3938127 0.0351894995 0.0309180965   11 95923692 95923874 183 - 0.000 0.300 14.384
ENSG00000087053 E046 6.5065285 0.0022628143 0.8010557397 0.931768271 11 95923875 95924000 126 - 0.854 0.882 0.108
ENSG00000087053 E047 4.5590002 0.0061936513 0.8816651723 0.962749714 11 95924001 95924131 131 - 0.742 0.725 -0.070
ENSG00000087053 E048 0.3766069 0.0165967537 0.2780292379   11 95924479 95924776 298 - 0.072 0.221 1.874
ENSG00000087053 E049 0.1316618 0.0122467812 0.2836568043   11 95925081 95925315 235 - 0.000 0.124 12.987

Help

Please Click HERE to learn more details about the results from DEXseq.