ENSG00000087589

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360314 ENSG00000087589 No_inf pgwt_inf CASS4 protein_coding protein_coding 11.28174 15.58014 7.033666 0.2573718 0.2400425 -1.146236 1.150454 0.6529734 1.178313 0.6529734 1.178313 0.8418922 0.1182333 0.042375 0.169775 0.127400 1.000000e+00 4.882745e-06 FALSE TRUE
ENST00000434344 ENSG00000087589 No_inf pgwt_inf CASS4 protein_coding protein_coding 11.28174 15.58014 7.033666 0.2573718 0.2400425 -1.146236 2.087437 4.1079704 0.000000 0.1380008 0.000000 -8.6857896 0.1513000 0.263550 0.000000 -0.263550 1.083370e-03 4.882745e-06 FALSE TRUE
ENST00000679529 ENSG00000087589 No_inf pgwt_inf CASS4 protein_coding protein_coding 11.28174 15.58014 7.033666 0.2573718 0.2400425 -1.146236 3.124055 8.9995392 0.000000 0.7295578 0.000000 -9.8153095 0.2039667 0.576650 0.000000 -0.576650 4.882745e-06 4.882745e-06 FALSE TRUE
ENST00000679887 ENSG00000087589 No_inf pgwt_inf CASS4 protein_coding protein_coding 11.28174 15.58014 7.033666 0.2573718 0.2400425 -1.146236 1.536489 0.0000000 2.660347 0.0000000 1.770313 8.0608832 0.1800750 0.000000 0.358075 0.358075 8.383388e-01 4.882745e-06 FALSE TRUE
MSTRG.18436.6 ENSG00000087589 No_inf pgwt_inf CASS4 protein_coding   11.28174 15.58014 7.033666 0.2573718 0.2400425 -1.146236 3.251258 1.5842920 3.068484 0.3671703 1.352684 0.9493043 0.3345083 0.102400 0.454625 0.352225 9.928472e-01 4.882745e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000087589 E001 0.3598652 0.1478781736 2.932860e-01   20 56412112 56412214 103 + 0.225 0.071 -1.941
ENSG00000087589 E002 0.6051861 0.1587849446 2.819474e-01   20 56412260 56412260 1 + 0.305 0.131 -1.525
ENSG00000087589 E003 1.1122364 0.0546930831 5.584762e-01 0.815419040 20 56412261 56412307 47 + 0.372 0.275 -0.619
ENSG00000087589 E004 0.7527941 0.0271446762 9.576809e-01 0.989462412 20 56412308 56412336 29 + 0.225 0.232 0.059
ENSG00000087589 E005 1.6216357 0.0091297683 7.613511e-01 0.915355553 20 56412337 56412392 56 + 0.431 0.383 -0.263
ENSG00000087589 E006 2.8657146 0.0342915458 6.676538e-01 0.871104197 20 56412393 56412494 102 + 0.608 0.541 -0.303
ENSG00000087589 E007 1.5053194 0.0096709441 9.405750e-01 0.984722269 20 56423087 56423256 170 + 0.372 0.383 0.059
ENSG00000087589 E008 8.7394148 0.0017800256 1.846802e-02 0.137517846 20 56437164 56437424 261 + 1.098 0.877 -0.819
ENSG00000087589 E009 5.7260423 0.0027447150 3.388370e-03 0.044271473 20 56437425 56437586 162 + 0.992 0.673 -1.249
ENSG00000087589 E010 5.5496224 0.0519365601 1.519698e-01 0.451150150 20 56445900 56446001 102 + 0.910 0.720 -0.747
ENSG00000087589 E011 5.7476399 0.0592374635 7.571448e-01 0.913765213 20 56450599 56450679 81 + 0.830 0.787 -0.170
ENSG00000087589 E012 66.0002671 0.0002336160 1.816986e-01 0.494512269 20 56451819 56453129 1311 + 1.825 1.778 -0.157
ENSG00000087589 E013 1.2608694 0.0134442562 7.714084e-01 0.920052544 20 56453130 56453896 767 + 0.305 0.350 0.282
ENSG00000087589 E014 138.3072935 0.0001669082 3.616363e-05 0.001272066 20 56458340 56460567 2228 + 2.058 2.133 0.251

Help

Please Click HERE to learn more details about the results from DEXseq.