ENSG00000088808

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000202556 ENSG00000088808 No_inf pgwt_inf PPP1R13B protein_coding protein_coding 8.725255 16.64966 4.331722 0.6699336 0.303149 -1.94002 2.3706318 3.2131973 1.4525960 0.59291327 0.35988701 -1.1399612 0.33750000 0.190250 0.329425 0.139175 0.99284725 0.02483481 FALSE TRUE
ENST00000554432 ENSG00000088808 No_inf pgwt_inf PPP1R13B protein_coding retained_intron 8.725255 16.64966 4.331722 0.6699336 0.303149 -1.94002 0.7354080 1.4058388 0.2602945 0.45849334 0.08684714 -2.3890531 0.08367500 0.081900 0.057750 -0.024150 0.99284725 0.02483481   FALSE
ENST00000555391 ENSG00000088808 No_inf pgwt_inf PPP1R13B protein_coding protein_coding_CDS_not_defined 8.725255 16.64966 4.331722 0.6699336 0.303149 -1.94002 0.4526394 0.4405372 0.8004784 0.29737793 0.29178489 0.8471273 0.08228333 0.027825 0.192175 0.164350 0.77943628 0.02483481 FALSE TRUE
ENST00000555708 ENSG00000088808 No_inf pgwt_inf PPP1R13B protein_coding protein_coding_CDS_not_defined 8.725255 16.64966 4.331722 0.6699336 0.303149 -1.94002 0.2752825 0.8258476 0.0000000 0.40195365 0.00000000 -6.3851681 0.01731667 0.051950 0.000000 -0.051950 0.97700932 0.02483481   FALSE
ENST00000555825 ENSG00000088808 No_inf pgwt_inf PPP1R13B protein_coding retained_intron 8.725255 16.64966 4.331722 0.6699336 0.303149 -1.94002 0.5247613 1.0400262 0.3226201 0.16877126 0.08440119 -1.6584781 0.06121667 0.062950 0.074375 0.011425 1.00000000 0.02483481 TRUE FALSE
ENST00000556597 ENSG00000088808 No_inf pgwt_inf PPP1R13B protein_coding nonsense_mediated_decay 8.725255 16.64966 4.331722 0.6699336 0.303149 -1.94002 1.5032924 3.4439796 1.0658975 0.31933722 0.19823864 -1.6827190 0.14905833 0.206175 0.241000 0.034825 0.99323661 0.02483481 TRUE TRUE
ENST00000557082 ENSG00000088808 No_inf pgwt_inf PPP1R13B protein_coding nonsense_mediated_decay 8.725255 16.64966 4.331722 0.6699336 0.303149 -1.94002 0.3441785 0.1898576 0.1533186 0.05958725 0.06405060 -0.2912832 0.06467500 0.011275 0.035275 0.024000 0.99284725 0.02483481 FALSE TRUE
ENST00000557587 ENSG00000088808 No_inf pgwt_inf PPP1R13B protein_coding nonsense_mediated_decay 8.725255 16.64966 4.331722 0.6699336 0.303149 -1.94002 0.5972759 0.8787766 0.0000000 0.87877662 0.00000000 -6.4737490 0.05754167 0.057900 0.000000 -0.057900 1.00000000 0.02483481 TRUE FALSE
ENST00000557744 ENSG00000088808 No_inf pgwt_inf PPP1R13B protein_coding retained_intron 8.725255 16.64966 4.331722 0.6699336 0.303149 -1.94002 1.4967575 4.4902724 0.0000000 0.86289673 0.00000000 -8.8138685 0.08849167 0.265475 0.000000 -0.265475 0.02483481 0.02483481   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000088808 E001 0.1315150 0.0123322748 1.000000e+00   14 103733195 103733751 557 - 0.000 0.064 9.417
ENSG00000088808 E002 0.1315150 0.0123322748 1.000000e+00   14 103733752 103733752 1 - 0.000 0.064 11.828
ENSG00000088808 E003 3.6377569 0.0042765155 5.333354e-01 0.800855420 14 103733753 103733922 170 - 0.677 0.605 -0.310
ENSG00000088808 E004 13.2386178 0.0011996626 7.603096e-01 0.914735605 14 103733923 103734366 444 - 1.115 1.102 -0.047
ENSG00000088808 E005 17.2255189 0.0017588181 3.948345e-02 0.217013549 14 103734367 103734663 297 - 1.075 1.253 0.634
ENSG00000088808 E006 17.4241411 0.0009532992 1.724278e-01 0.481433960 14 103734664 103734891 228 - 1.127 1.245 0.420
ENSG00000088808 E007 2.4098740 0.0059314718 7.864954e-01 0.925941640 14 103734892 103734892 1 - 0.459 0.510 0.249
ENSG00000088808 E008 6.1416406 0.0023816075 3.996097e-01 0.711514324 14 103734893 103734983 91 - 0.869 0.786 -0.324
ENSG00000088808 E009 3.6180508 0.0043461037 3.123466e-01 0.638281447 14 103734984 103734999 16 - 0.710 0.588 -0.526
ENSG00000088808 E010 6.9937130 0.0019417856 1.768860e-01 0.488156035 14 103735000 103735079 80 - 0.949 0.818 -0.499
ENSG00000088808 E011 4.9174042 0.0037242160 8.253381e-01 0.940985670 14 103735080 103735113 34 - 0.741 0.725 -0.066
ENSG00000088808 E012 5.4262710 0.0052783492 8.750007e-01 0.960490350 14 103735114 103735195 82 - 0.770 0.762 -0.030
ENSG00000088808 E013 11.6643762 0.0072592703 2.826524e-01 0.610402456 14 103736003 103736202 200 - 1.115 1.031 -0.306
ENSG00000088808 E014 4.8514691 0.0031166860 2.568328e-01 0.584531224 14 103736203 103737693 1491 - 0.603 0.762 0.670
ENSG00000088808 E015 3.4750101 0.1263649655 2.440289e-01 0.570232457 14 103737694 103737710 17 - 0.741 0.551 -0.821
ENSG00000088808 E016 8.1403696 0.0023573038 2.759122e-01 0.604166535 14 103737711 103737860 150 - 0.984 0.886 -0.368
ENSG00000088808 E017 2.1822510 0.0175877020 2.883486e-01 0.615955237 14 103738389 103738678 290 - 0.328 0.510 0.986
ENSG00000088808 E018 6.8952418 0.0023298931 3.839416e-01 0.699510375 14 103738679 103738812 134 - 0.911 0.829 -0.314
ENSG00000088808 E019 4.9337842 0.0031973934 8.991967e-01 0.969876768 14 103738886 103739023 138 - 0.710 0.738 0.112
ENSG00000088808 E020 0.0000000       14 103739024 103739272 249 -      
ENSG00000088808 E021 10.7296002 0.0021441568 9.595042e-01 0.990182495 14 103739824 103740063 240 - 1.017 1.024 0.027
ENSG00000088808 E022 18.7465593 0.0009047881 5.575062e-01 0.815078971 14 103740064 103740593 530 - 1.205 1.261 0.197
ENSG00000088808 E023 6.9911128 0.0023374445 1.782807e-01 0.490243225 14 103741790 103741991 202 - 0.949 0.818 -0.499
ENSG00000088808 E024 3.8791096 0.0126120315 4.611530e-01 0.755034050 14 103741992 103742088 97 - 0.710 0.622 -0.374
ENSG00000088808 E025 9.1298356 0.0016360180 6.025216e-01 0.838676539 14 103742089 103742291 203 - 0.911 0.976 0.244
ENSG00000088808 E026 6.6267435 0.0024398067 3.250130e-01 0.649486200 14 103742654 103742823 170 - 0.741 0.868 0.501
ENSG00000088808 E027 3.2848247 0.0073880101 8.367701e-05 0.002551452 14 103742824 103743078 255 - 0.000 0.698 15.599
ENSG00000088808 E028 0.9021618 0.0126959106 3.693488e-01 0.687708345 14 103743891 103744015 125 - 0.139 0.292 1.349
ENSG00000088808 E029 0.4915678 0.0636082604 3.975163e-01   14 103746373 103746373 1 - 0.243 0.120 -1.237
ENSG00000088808 E030 4.3397516 0.0034132362 8.575090e-02 0.335246816 14 103746374 103746553 180 - 0.822 0.622 -0.821
ENSG00000088808 E031 0.2617264 0.3666584361 8.842543e-01   14 103746652 103746707 56 - 0.000 0.120 12.439
ENSG00000088808 E032 0.3936739 0.0161644127 4.281319e-01   14 103746708 103746772 65 - 0.000 0.170 13.218
ENSG00000088808 E033 0.3936739 0.0161644127 4.281319e-01   14 103746773 103746860 88 - 0.000 0.170 13.218
ENSG00000088808 E034 1.1813797 0.0108008001 3.082855e-02 0.187421485 14 103746933 103747397 465 - 0.000 0.387 14.494
ENSG00000088808 E035 4.3277557 0.0133425499 4.819756e-01 0.769139773 14 103749794 103749934 141 - 0.603 0.712 0.464
ENSG00000088808 E036 3.9927925 0.0402449172 3.863902e-01 0.700975378 14 103753000 103753196 197 - 0.741 0.622 -0.499
ENSG00000088808 E037 3.8008864 0.0794649110 7.355808e-01 0.903909290 14 103754070 103754164 95 - 0.603 0.654 0.224
ENSG00000088808 E038 2.9190194 0.0051948380 7.471433e-01 0.909421059 14 103754165 103754238 74 - 0.513 0.570 0.266
ENSG00000088808 E039 0.9832416 0.0201374952 2.224964e-01 0.546561052 14 103754239 103754244 6 - 0.399 0.214 -1.236
ENSG00000088808 E040 0.1311489 0.0124019058 1.000000e+00   14 103757649 103757649 1 - 0.000 0.064 11.828
ENSG00000088808 E041 4.0148118 0.0038147835 5.226990e-01 0.794324666 14 103757650 103757751 102 - 0.710 0.638 -0.304
ENSG00000088808 E042 0.1311489 0.0124019058 1.000000e+00   14 103759191 103759305 115 - 0.000 0.064 11.828
ENSG00000088808 E043 1.1131519 0.0112516999 3.353291e-01 0.658342427 14 103763863 103764479 617 - 0.398 0.255 -0.914
ENSG00000088808 E044 0.1311489 0.0124019058 1.000000e+00   14 103778592 103778744 153 - 0.000 0.064 11.828
ENSG00000088808 E045 2.1468415 0.0065391075 9.790266e-01 0.997305921 14 103778745 103778754 10 - 0.459 0.464 0.027
ENSG00000088808 E046 3.2775612 0.0045377018 8.542830e-01 0.952660869 14 103778755 103778821 67 - 0.603 0.588 -0.066
ENSG00000088808 E047 1.9992831 0.0073239615 4.745320e-01 0.764262863 14 103784795 103784914 120 - 0.513 0.414 -0.499
ENSG00000088808 E048 0.0000000       14 103794577 103794663 87 -      
ENSG00000088808 E049 1.4903515 0.0108627258 3.595235e-01 0.679205163 14 103797371 103797518 148 - 0.459 0.326 -0.751
ENSG00000088808 E050 0.0000000       14 103840079 103840107 29 -      
ENSG00000088808 E051 0.0000000       14 103846775 103846885 111 -      
ENSG00000088808 E052 0.0000000       14 103847008 103847298 291 -      
ENSG00000088808 E053 2.6879411 0.0110975599 2.966898e-01 0.624482586 14 103847299 103847541 243 - 0.398 0.570 0.851
ENSG00000088808 E054 1.0330378 0.0117194362 2.732415e-01 0.601606831 14 103847542 103847575 34 - 0.139 0.326 1.571

Help

Please Click HERE to learn more details about the results from DEXseq.