ENSG00000090530

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000319332 ENSG00000090530 No_inf pgwt_inf P3H2 protein_coding protein_coding 148.1301 2.950188 224.4983 0.2581974 8.519816 6.244936 50.98323 0.3897086 81.74657 0.2411388 4.298570 7.676242 0.2779417 0.1409 0.366200 0.225300 0.89047964 0.03916143 FALSE TRUE
ENST00000427335 ENSG00000090530 No_inf pgwt_inf P3H2 protein_coding protein_coding 148.1301 2.950188 224.4983 0.2581974 8.519816 6.244936 49.49753 2.4450941 78.02864 0.3439431 5.730781 4.990338 0.4955500 0.8220 0.348575 -0.473425 0.21672325 0.03916143 FALSE TRUE
ENST00000490940 ENSG00000090530 No_inf pgwt_inf P3H2 protein_coding retained_intron 148.1301 2.950188 224.4983 0.2581974 8.519816 6.244936 45.91831 0.0000000 61.59038 0.0000000 8.935981 12.588723 0.2066500 0.0000 0.271275 0.271275 0.03916143 0.03916143   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000090530 E001 7.6622756 2.983585e-03 1.0000000000 1.00000000 3 189956728 189956830 103 - 0.485 0.466 -0.097
ENSG00000090530 E002 370.4011427 6.000190e-05 0.0050242545 0.05841384 3 189956831 189957696 866 - 1.998 2.132 0.448
ENSG00000090530 E003 203.4563992 9.129339e-05 0.0283172871 0.17825821 3 189957697 189958004 308 - 1.748 1.552 -0.666
ENSG00000090530 E004 1.1393749 5.635322e-02 1.0000000000 1.00000000 3 189963459 189963957 499 - 0.118 0.000 -8.570
ENSG00000090530 E005 87.1585240 6.296415e-04 0.7384088836 0.90533452 3 189963958 189964049 92 - 1.388 1.345 -0.146
ENSG00000090530 E006 61.7903028 4.749724e-03 0.8925301426 0.96739057 3 189964050 189964098 49 - 1.244 1.263 0.064
ENSG00000090530 E007 0.0000000       3 189964099 189964121 23 -      
ENSG00000090530 E008 74.8020058 2.845237e-04 0.6499988839 0.86258133 3 189970816 189970891 76 - 1.324 1.263 -0.216
ENSG00000090530 E009 0.1141751 1.140299e-02 0.0446309024   3 189971548 189971889 342 - 0.013 0.000 -5.859
ENSG00000090530 E010 84.8560789 1.688713e-04 0.5818374009 0.82774810 3 189971890 189972007 118 - 1.377 1.306 -0.247
ENSG00000090530 E011 108.4785529 1.317902e-04 0.0472205035 0.23969647 3 189972874 189973024 151 - 1.474 1.655 0.619
ENSG00000090530 E012 0.2279811 1.555936e-02 0.1136898853   3 189973025 189973184 160 - 0.026 0.000 -6.757
ENSG00000090530 E013 69.9473986 1.236252e-03 0.1897808708 0.50426484 3 189973909 189974004 96 - 1.299 1.098 -0.711
ENSG00000090530 E014 0.5699629 3.985651e-02 0.4384157075   3 189974005 189974190 186 - 0.063 0.000 -7.731
ENSG00000090530 E015 34.7772202 7.376942e-04 0.9389242377 0.98381457 3 189974558 189974567 10 - 1.014 1.026 0.045
ENSG00000090530 E016 34.3199688 5.069914e-04 0.9150058989 0.97485305 3 189974568 189974572 5 - 1.008 1.026 0.064
ENSG00000090530 E017 81.3050217 2.041544e-04 0.6850992853 0.87990242 3 189974573 189974685 113 - 1.359 1.306 -0.184
ENSG00000090530 E018 73.7163013 2.010166e-04 0.3927081622 0.70592929 3 189983046 189983140 95 - 1.315 1.415 0.346
ENSG00000090530 E019 0.1138060 1.134772e-02 0.0446400334   3 189983141 189983484 344 - 0.013 0.000 -5.861
ENSG00000090530 E020 46.5383548 2.933987e-04 0.0457750383 0.23518088 3 189984550 189984590 41 - 1.123 1.382 0.910
ENSG00000090530 E021 64.0348988 1.924074e-03 0.1052435558 0.37441090 3 189986788 189986877 90 - 1.255 1.446 0.664
ENSG00000090530 E022 96.9457174 1.681383e-04 0.1812825818 0.49413740 3 189987527 189987669 143 - 1.434 1.263 -0.596
ENSG00000090530 E023 0.4555123 5.052220e-02 0.3001937342   3 189987670 189987765 96 - 0.051 0.000 -7.337
ENSG00000090530 E024 35.3189987 3.820585e-04 0.3456322571 0.66697491 3 189988907 189988914 8 - 1.023 0.831 -0.725
ENSG00000090530 E025 80.9234002 1.666067e-04 0.1621417666 0.46592280 3 189988915 189989038 124 - 1.359 1.160 -0.699
ENSG00000090530 E026 99.4586581 1.456700e-04 0.5508314647 0.81123265 3 189994094 189994283 190 - 1.441 1.502 0.211
ENSG00000090530 E027 55.3208581 6.082943e-03 0.3023635621 0.62946165 3 189995290 189995442 153 - 1.202 1.026 -0.635
ENSG00000090530 E028 0.0000000       3 190116580 190116648 69 -      
ENSG00000090530 E029 90.5730534 4.436893e-04 0.0008897996 0.01643560 3 190120252 190120897 646 - 1.409 0.831 -2.094
ENSG00000090530 E030 0.1139502 1.138185e-02 0.0446321781   3 190121537 190121678 142 - 0.013 0.000 -5.860
ENSG00000090530 E031 0.1138060 1.134772e-02 0.0446400334   3 190122203 190122437 235 - 0.013 0.000 -5.861

Help

Please Click HERE to learn more details about the results from DEXseq.