ENSG00000099785

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000215555 ENSG00000099785 No_inf pgwt_inf MARCHF2 protein_coding protein_coding 17.00625 25.32998 11.08011 2.525728 0.8191034 -1.192142 4.8121727 9.130838 1.2263558 2.0824988 1.2263558 -2.8862325 0.24287500 0.354725 0.100975 -0.253750 0.35046536 0.01188967 FALSE TRUE
ENST00000381035 ENSG00000099785 No_inf pgwt_inf MARCHF2 protein_coding protein_coding 17.00625 25.32998 11.08011 2.525728 0.8191034 -1.192142 0.9919072 1.214000 0.8742423 0.1906822 0.8742423 -0.4690904 0.06725833 0.048875 0.068625 0.019750 0.99284725 0.01188967 FALSE TRUE
ENST00000594796 ENSG00000099785 No_inf pgwt_inf MARCHF2 protein_coding retained_intron 17.00625 25.32998 11.08011 2.525728 0.8191034 -1.192142 2.2897755 0.000000 2.8794611 0.0000000 1.7030812 8.1746566 0.15183333 0.000000 0.230675 0.230675 0.88304757 0.01188967 FALSE FALSE
ENST00000601724 ENSG00000099785 No_inf pgwt_inf MARCHF2 protein_coding protein_coding 17.00625 25.32998 11.08011 2.525728 0.8191034 -1.192142 0.9096279 1.390262 0.0000000 1.3902615 0.0000000 -7.1295525 0.05071667 0.043425 0.000000 -0.043425 1.00000000 0.01188967 FALSE FALSE
ENST00000602117 ENSG00000099785 No_inf pgwt_inf MARCHF2 protein_coding protein_coding 17.00625 25.32998 11.08011 2.525728 0.8191034 -1.192142 1.4048117 3.915442 0.0000000 0.9793047 0.0000000 -8.6167111 0.05647500 0.153300 0.000000 -0.153300 0.01188967 0.01188967 FALSE TRUE
MSTRG.14450.11 ENSG00000099785 No_inf pgwt_inf MARCHF2 protein_coding   17.00625 25.32998 11.08011 2.525728 0.8191034 -1.192142 1.3893964 2.684317 1.1337788 1.5848219 0.6604197 -1.2361113 0.07911667 0.115325 0.103150 -0.012175 1.00000000 0.01188967 FALSE TRUE
MSTRG.14450.2 ENSG00000099785 No_inf pgwt_inf MARCHF2 protein_coding   17.00625 25.32998 11.08011 2.525728 0.8191034 -1.192142 2.3649966 2.190939 1.5585118 2.1909387 0.9262626 -0.4887226 0.17100833 0.106950 0.149450 0.042500 0.99284725 0.01188967 FALSE TRUE
MSTRG.14450.7 ENSG00000099785 No_inf pgwt_inf MARCHF2 protein_coding   17.00625 25.32998 11.08011 2.525728 0.8191034 -1.192142 1.1314736 3.161919 0.0000000 3.1619192 0.0000000 -8.3092122 0.04432500 0.120425 0.000000 -0.120425 1.00000000 0.01188967 FALSE TRUE
MSTRG.14450.8 ENSG00000099785 No_inf pgwt_inf MARCHF2 protein_coding   17.00625 25.32998 11.08011 2.525728 0.8191034 -1.192142 1.0292878 0.000000 3.0878635 0.0000000 1.8894779 8.2751297 0.10488333 0.000000 0.314650 0.314650 0.95599749 0.01188967 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000099785 E001 0.0000000       19 8413270 8413289 20 +      
ENSG00000099785 E002 0.0000000       19 8413290 8413294 5 +      
ENSG00000099785 E003 0.2631768 0.0162879725 1.000000000   19 8413295 8413304 10 + 0.000 0.103 8.979
ENSG00000099785 E004 0.2631768 0.0162879725 1.000000000   19 8413305 8413307 3 + 0.000 0.103 10.680
ENSG00000099785 E005 4.2843067 0.0491248930 0.066925204 0.29279639 19 8413308 8413340 33 + 0.370 0.700 1.578
ENSG00000099785 E006 6.1683254 0.0097928114 0.322016383 0.64666962 19 8413341 8413420 80 + 0.661 0.803 0.578
ENSG00000099785 E007 2.0487905 0.0071040096 0.705954374 0.89010982 19 8413422 8413794 373 + 0.370 0.438 0.371
ENSG00000099785 E008 1.7847547 0.0226725173 0.916334814 0.97529219 19 8416958 8417151 194 + 0.370 0.393 0.130
ENSG00000099785 E009 1.8390955 0.0095831418 0.017567924 0.13372682 19 8418405 8418536 132 + 0.000 0.458 13.071
ENSG00000099785 E010 0.9195145 0.0122515783 0.147510112 0.44418746 19 8418537 8418538 2 + 0.000 0.287 12.258
ENSG00000099785 E011 7.9859090 0.0115801226 0.118525145 0.39843122 19 8418539 8418741 203 + 0.702 0.908 0.814
ENSG00000099785 E012 7.0992433 0.0020513476 0.058942758 0.27277790 19 8418742 8418807 66 + 0.617 0.870 1.033
ENSG00000099785 E013 15.4147763 0.0009541223 0.094843910 0.35409549 19 8421789 8421926 138 + 0.998 1.158 0.578
ENSG00000099785 E014 9.7741837 0.0015782661 0.131248071 0.42017981 19 8421927 8421951 25 + 0.805 0.980 0.671
ENSG00000099785 E015 10.6702340 0.0172391345 0.634665419 0.85449411 19 8421952 8422016 65 + 1.017 0.974 -0.159
ENSG00000099785 E016 21.8772942 0.0008912022 0.063187065 0.28337827 19 8426609 8426804 196 + 1.361 1.245 -0.405
ENSG00000099785 E017 25.1008779 0.0006569600 0.194600303 0.51078130 19 8430658 8430867 210 + 1.386 1.312 -0.255
ENSG00000099785 E018 0.1141751 0.0112492854 0.126027102   19 8430868 8430892 25 + 0.161 0.000 -13.149
ENSG00000099785 E019 23.6938170 0.0011944538 0.994584505 1.00000000 19 8438388 8438534 147 + 1.297 1.307 0.033
ENSG00000099785 E020 30.2824715 0.0010389109 0.006372381 0.06864251 19 8438535 8439017 483 + 1.516 1.373 -0.493

Help

Please Click HERE to learn more details about the results from DEXseq.