ENSG00000100320

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000397303 ENSG00000100320 No_inf pgwt_inf RBFOX2 protein_coding protein_coding 10.5816 12.14261 10.83184 3.843014 3.6322 -0.1646566 2.7356425 0.2594538 4.139579 0.2594538 0.3446183 3.9448550 0.31265833 0.012850 0.47780 0.464950 0.020863335 0.003966821 FALSE TRUE
ENST00000408983 ENSG00000100320 No_inf pgwt_inf RBFOX2 protein_coding protein_coding 10.5816 12.14261 10.83184 3.843014 3.6322 -0.1646566 0.3890171 0.5255457 0.000000 0.5255457 0.0000000 -5.7429378 0.05081667 0.095975 0.00000 -0.095975 0.993236612 0.003966821 FALSE FALSE
ENST00000438146 ENSG00000100320 No_inf pgwt_inf RBFOX2 protein_coding protein_coding 10.5816 12.14261 10.83184 3.843014 3.6322 -0.1646566 0.8926561 0.1167463 1.113275 0.1167463 0.7045956 3.1476960 0.10637500 0.006775 0.15535 0.148575 0.992847247 0.003966821 FALSE TRUE
MSTRG.19332.23 ENSG00000100320 No_inf pgwt_inf RBFOX2 protein_coding   10.5816 12.14261 10.83184 3.843014 3.6322 -0.1646566 3.6649329 7.2794388 3.715360 4.2328885 3.7153599 -0.9684279 0.18683333 0.388800 0.17170 -0.217100 0.992847247 0.003966821   FALSE
MSTRG.19332.4 ENSG00000100320 No_inf pgwt_inf RBFOX2 protein_coding   10.5816 12.14261 10.83184 3.843014 3.6322 -0.1646566 1.5878716 2.7643456 0.000000 0.2302261 0.0000000 -8.1160037 0.18097500 0.307550 0.00000 -0.307550 0.003966821 0.003966821 FALSE TRUE
MSTRG.19332.6 ENSG00000100320 No_inf pgwt_inf RBFOX2 protein_coding   10.5816 12.14261 10.83184 3.843014 3.6322 -0.1646566 1.0056594 0.7926078 1.766941 0.3291545 0.7260890 1.1466288 0.12330833 0.125850 0.18300 0.057150 0.992847247 0.003966821 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000100320 E001 0.1141751 0.0112822227 6.116364e-01   22 35738736 35738737 2 - 0.090 0.000 -11.063
ENSG00000100320 E002 0.3767001 0.0170142157 5.075905e-01   22 35738738 35738757 20 - 0.090 0.183 1.195
ENSG00000100320 E003 1.0177953 0.1253906730 1.561232e-01 4.573757e-01 22 35738758 35738793 36 - 0.164 0.410 1.780
ENSG00000100320 E004 93.8494676 0.0002207972 2.226616e-10 2.504283e-08 22 35738794 35743601 4808 - 1.895 2.045 0.504
ENSG00000100320 E005 4.1864955 0.0039138144 4.785975e-01 7.666162e-01 22 35743602 35743932 331 - 0.669 0.757 0.365
ENSG00000100320 E006 0.3938931 0.0181501262 8.159010e-02   22 35743933 35743957 25 - 0.000 0.252 14.225
ENSG00000100320 E007 0.1315150 0.0121773104 4.732315e-01   22 35743958 35743962 5 - 0.000 0.101 12.816
ENSG00000100320 E008 0.1315150 0.0121773104 4.732315e-01   22 35743963 35743982 20 - 0.000 0.101 12.816
ENSG00000100320 E009 2.7165995 0.0054300837 4.732615e-01 7.632164e-01 22 35743983 35744077 95 - 0.517 0.617 0.458
ENSG00000100320 E010 2.4550102 0.0059678547 7.777910e-01 9.227114e-01 22 35744078 35744086 9 - 0.517 0.559 0.195
ENSG00000100320 E011 2.0621252 0.0092600067 6.443966e-01 8.595949e-01 22 35744087 35744124 38 - 0.517 0.452 -0.320
ENSG00000100320 E012 1.3590514 0.0375055243 6.389921e-01 8.567991e-01 22 35744125 35744147 23 - 0.331 0.410 0.458
ENSG00000100320 E013 1.3417115 0.0134072761 9.245372e-01 9.786246e-01 22 35744148 35744163 16 - 0.375 0.364 -0.068
ENSG00000100320 E014 4.1041650 0.0044737599 3.152727e-01 6.411903e-01 22 35744164 35744232 69 - 0.764 0.644 -0.497
ENSG00000100320 E015 3.3686290 0.0044605616 2.382473e-01 5.639198e-01 22 35744233 35744249 17 - 0.709 0.559 -0.653
ENSG00000100320 E016 3.5606791 0.0041976519 2.439824e-02 1.629599e-01 22 35745923 35745995 73 - 0.781 0.491 -1.265
ENSG00000100320 E017 4.0429808 0.0041020202 8.508406e-01 9.512240e-01 22 35746473 35746561 89 - 0.689 0.715 0.107
ENSG00000100320 E018 1.1320256 0.1444660860 3.158019e-01 6.417341e-01 22 35746562 35750183 3622 - 0.227 0.410 1.195
ENSG00000100320 E019 0.0000000       22 35750184 35750260 77 -      
ENSG00000100320 E020 0.1308632 0.0122779492 4.729000e-01   22 35750426 35750457 32 - 0.000 0.101 12.816
ENSG00000100320 E021 0.3932413 0.0221514376 8.187139e-02   22 35752613 35752655 43 - 0.000 0.252 14.219
ENSG00000100320 E022 4.6314246 0.0300848841 8.311493e-01 9.433642e-01 22 35756105 35756144 40 - 0.764 0.737 -0.110
ENSG00000100320 E023 7.7037410 0.0348403190 1.687705e-01 4.757009e-01 22 35759888 35760009 122 - 1.016 0.847 -0.640
ENSG00000100320 E024 2.5960258 0.0059756658 2.036770e-02 1.457727e-01 22 35760010 35760020 11 - 0.689 0.364 -1.571
ENSG00000100320 E025 1.4377915 0.0328984510 3.673431e-01 6.861155e-01 22 35760021 35760032 12 - 0.452 0.311 -0.805
ENSG00000100320 E026 5.8682317 0.0028251343 4.450767e-02 2.318669e-01 22 35761202 35761294 93 - 0.932 0.715 -0.850
ENSG00000100320 E027 5.5402735 0.0027966898 1.771745e-01 4.884190e-01 22 35761415 35761468 54 - 0.883 0.737 -0.576
ENSG00000100320 E028 0.0000000       22 35763437 35763556 120 -      
ENSG00000100320 E029 5.5060655 0.0026860524 5.026690e-02 2.486599e-01 22 35765423 35765483 61 - 0.908 0.693 -0.853
ENSG00000100320 E030 0.1316618 0.0123957587 4.727969e-01   22 35767368 35767441 74 - 0.000 0.101 12.816
ENSG00000100320 E031 2.6478120 0.0674061855 3.801400e-01 6.965712e-01 22 35768257 35768267 11 - 0.624 0.491 -0.612
ENSG00000100320 E032 5.8850263 0.0030207797 8.520323e-02 3.341945e-01 22 35768268 35768341 74 - 0.920 0.737 -0.718
ENSG00000100320 E033 3.8414403 0.0180820851 1.731937e-01 4.824813e-01 22 35768342 35768349 8 - 0.764 0.589 -0.738
ENSG00000100320 E034 0.3933882 0.0322208591 8.268065e-02   22 35772931 35772971 41 - 0.000 0.252 14.204
ENSG00000100320 E035 0.1315150 0.0121773104 4.732315e-01   22 35777656 35778024 369 - 0.000 0.101 12.816
ENSG00000100320 E036 3.8414403 0.0180820851 1.731937e-01 4.824813e-01 22 35778025 35778027 3 - 0.764 0.589 -0.738
ENSG00000100320 E037 3.7099253 0.0083313451 1.056226e-01 3.752639e-01 22 35778028 35778056 29 - 0.764 0.559 -0.876
ENSG00000100320 E038 2.4196977 0.0132892197 5.449090e-01 8.080121e-01 22 35778057 35778075 19 - 0.574 0.491 -0.390
ENSG00000100320 E039 1.8139477 0.0488141510 6.246076e-01 8.497818e-01 22 35778076 35778078 3 - 0.486 0.410 -0.390
ENSG00000100320 E040 4.8540360 0.0047317774 5.833360e-01 8.286364e-01 22 35781600 35781743 144 - 0.797 0.737 -0.241
ENSG00000100320 E041 0.8155244 0.0139952948 7.117318e-02 3.027783e-01 22 35781744 35781746 3 - 0.375 0.101 -2.390
ENSG00000100320 E042 0.2454678 0.0163585482 9.215280e-01   22 35781937 35781994 58 - 0.090 0.101 0.195
ENSG00000100320 E043 6.0803904 0.1270613089 7.050488e-01 8.896257e-01 22 35809780 35810004 225 - 0.870 0.830 -0.153
ENSG00000100320 E044 0.0000000       22 35824320 35824373 54 -      
ENSG00000100320 E045 0.0000000       22 35836320 35836439 120 -      
ENSG00000100320 E046 0.0000000       22 35840192 35840587 396 -      
ENSG00000100320 E047 1.1750612 0.0108099870 7.914704e-02 3.210269e-01 22 35938847 35938897 51 - 0.452 0.183 -1.805
ENSG00000100320 E048 0.0000000       22 35961463 35961534 72 -      
ENSG00000100320 E049 0.0000000       22 35961563 35961666 104 -      
ENSG00000100320 E050 2.4834456 0.0061150953 3.074571e-02 1.872180e-01 22 36028240 36028824 585 - 0.669 0.364 -1.483

Help

Please Click HERE to learn more details about the results from DEXseq.