ENSG00000100413

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000337566 ENSG00000100413 No_inf pgwt_inf POLR3H protein_coding protein_coding 28.14604 16.54408 32.98461 2.207635 2.604794 0.9950439 4.117118 0.0000000 8.818476 0.0000000 1.9745054 9.7860206 0.13000833 0.000000 0.282100 0.282100 0.0007339123 0.0007339123 FALSE TRUE
ENST00000355209 ENSG00000100413 No_inf pgwt_inf POLR3H protein_coding protein_coding 28.14604 16.54408 32.98461 2.207635 2.604794 0.9950439 4.394233 2.8640438 5.892526 0.9765866 0.2777099 1.0382504 0.17239167 0.201350 0.182750 -0.018600 1.0000000000 0.0007339123 FALSE TRUE
ENST00000407461 ENSG00000100413 No_inf pgwt_inf POLR3H protein_coding protein_coding 28.14604 16.54408 32.98461 2.207635 2.604794 0.9950439 9.571182 6.7756835 10.569128 1.3353177 0.8628728 0.6406546 0.35205000 0.405900 0.320400 -0.085500 0.9928472467 0.0007339123 FALSE TRUE
ENST00000420561 ENSG00000100413 No_inf pgwt_inf POLR3H protein_coding protein_coding_CDS_not_defined 28.14604 16.54408 32.98461 2.207635 2.604794 0.9950439 5.788360 3.8838961 4.510896 2.4187775 2.8500717 0.2153943 0.18728333 0.198275 0.119625 -0.078650 0.9928472467 0.0007339123   FALSE
ENST00000431534 ENSG00000100413 No_inf pgwt_inf POLR3H protein_coding nonsense_mediated_decay 28.14604 16.54408 32.98461 2.207635 2.604794 0.9950439 1.842116 0.3821866 1.541528 0.3821866 0.6890344 1.9840779 0.05720833 0.029550 0.043550 0.014000 0.9928472467 0.0007339123 FALSE TRUE
ENST00000442616 ENSG00000100413 No_inf pgwt_inf POLR3H protein_coding nonsense_mediated_decay 28.14604 16.54408 32.98461 2.207635 2.604794 0.9950439 1.005987 1.2559929 1.015057 0.5026970 0.3979104 -0.3045650 0.04839167 0.089700 0.029625 -0.060075 0.9928472467 0.0007339123   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000100413 E001 0.0000000       22 41525799 41525803 5 -      
ENSG00000100413 E002 22.6739613 0.0117676958 0.003177238 0.04232544 22 41525804 41528841 3038 - 1.268 1.476 0.722
ENSG00000100413 E003 0.0000000       22 41528842 41528842 1 -      
ENSG00000100413 E004 0.0000000       22 41528843 41528864 22 -      
ENSG00000100413 E005 0.0000000       22 41528865 41529211 347 -      
ENSG00000100413 E006 5.5353698 0.0027225744 0.169016532 0.47616683 22 41529212 41529336 125 - 0.839 0.677 -0.651
ENSG00000100413 E007 28.6092548 0.0005226949 0.840610021 0.94726323 22 41530687 41530888 202 - 1.446 1.442 -0.014
ENSG00000100413 E008 8.2977805 0.0016370214 0.406452051 0.71588963 22 41532094 41532118 25 - 0.968 0.890 -0.294
ENSG00000100413 E009 9.8359931 0.0015978366 0.320493749 0.64528406 22 41532119 41532157 39 - 1.037 0.949 -0.325
ENSG00000100413 E010 0.4742377 0.0155085716 0.888951579   22 41532604 41532624 21 - 0.170 0.139 -0.348
ENSG00000100413 E011 0.8497700 0.0140765451 0.480649908 0.76808492 22 41532625 41532658 34 - 0.214 0.328 0.822
ENSG00000100413 E012 14.9541910 0.0010557505 0.636745277 0.85547186 22 41532659 41532745 87 - 1.163 1.205 0.149
ENSG00000100413 E013 1.8840432 0.0092909695 0.003925493 0.04902110 22 41533522 41533687 166 - 0.255 0.677 2.237
ENSG00000100413 E014 2.2923741 0.2363663462 0.536748297 0.80302096 22 41539143 41540698 1556 - 0.465 0.560 0.458
ENSG00000100413 E015 14.6980846 0.0223458450 0.379356810 0.69614174 22 41540699 41540795 97 - 1.195 1.115 -0.286
ENSG00000100413 E016 0.2461098 0.0161674791 0.510451888   22 41543752 41543990 239 - 0.064 0.139 1.237
ENSG00000100413 E017 16.9525363 0.0010133065 0.239153914 0.56496469 22 41543991 41544121 131 - 1.253 1.173 -0.282
ENSG00000100413 E018 23.7334200 0.0006575622 0.223531487 0.54769651 22 41544122 41544427 306 - 1.388 1.321 -0.235
ENSG00000100413 E019 0.2454678 0.0161425593 0.510703744   22 41544428 41544489 62 - 0.064 0.139 1.237
ENSG00000100413 E020 0.0000000       22 41544511 41544606 96 -      

Help

Please Click HERE to learn more details about the results from DEXseq.