ENSG00000101337

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000398022 ENSG00000101337 No_inf pgwt_inf TM9SF4 protein_coding protein_coding 34.32496 24.62529 40.65151 0.835789 0.8112863 0.7229375 29.756350 15.044319 39.40575 1.0839541 0.7724935 1.388595 0.83432500 0.609275 0.9697 0.360425 5.285245e-03 3.500941e-07 FALSE TRUE
ENST00000479591 ENSG00000101337 No_inf pgwt_inf TM9SF4 protein_coding retained_intron 34.32496 24.62529 40.65151 0.835789 0.8112863 0.7229375 1.989849 5.969548 0.00000 0.4340663 0.0000000 -9.223893 0.08063333 0.241900 0.0000 -0.241900 3.500941e-07 3.500941e-07   FALSE
MSTRG.18131.6 ENSG00000101337 No_inf pgwt_inf TM9SF4 protein_coding   34.32496 24.62529 40.65151 0.835789 0.8112863 0.7229375 1.627437 2.544821 0.00000 0.9279840 0.0000000 -7.997078 0.05611667 0.106400 0.0000 -0.106400 2.041989e-03 3.500941e-07 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000101337 E001 0.0000000       20 32109714 32109716 3 +      
ENSG00000101337 E002 0.2448134 1.599119e-02 6.124635e-01   20 32109717 32109727 11 + 0.071 0.127 0.938
ENSG00000101337 E003 0.7017592 1.451023e-02 3.486829e-01 6.693976e-01 20 32109728 32109735 8 + 0.275 0.127 -1.384
ENSG00000101337 E004 3.2190451 4.458015e-03 6.073317e-01 8.413605e-01 20 32109736 32109755 20 + 0.640 0.569 -0.310
ENSG00000101337 E005 0.0000000       20 32109756 32109766 11 +      
ENSG00000101337 E006 0.2291896 2.629523e-01 6.261597e-01   20 32109767 32110039 273 + 0.132 0.000 -10.820
ENSG00000101337 E007 0.2626639 1.599408e-02 8.812446e-02   20 32131883 32131924 42 + 0.000 0.225 11.935
ENSG00000101337 E008 12.7620374 1.111622e-03 3.333262e-01 6.567064e-01 20 32133013 32133126 114 + 1.154 1.073 -0.291
ENSG00000101337 E009 16.4174869 9.888204e-03 1.738507e-01 4.835061e-01 20 32136074 32136173 100 + 1.267 1.153 -0.406
ENSG00000101337 E010 0.3769730 1.682426e-02 2.603337e-01   20 32136877 32136997 121 + 0.071 0.225 1.938
ENSG00000101337 E011 17.5128594 9.505565e-04 1.919269e-01 5.072071e-01 20 32141497 32141540 44 + 1.288 1.192 -0.336
ENSG00000101337 E012 26.3202405 5.636422e-04 8.793735e-02 3.402509e-01 20 32141541 32141665 125 + 1.459 1.356 -0.357
ENSG00000101337 E013 23.0014994 5.719968e-03 1.923195e-02 1.404580e-01 20 32141766 32141895 130 + 1.423 1.254 -0.588
ENSG00000101337 E014 17.7461085 7.769867e-04 1.556397e-01 4.567073e-01 20 32142982 32143077 96 + 1.296 1.192 -0.364
ENSG00000101337 E015 11.6299325 1.200616e-03 9.926337e-02 3.632032e-01 20 32143078 32143105 28 + 1.138 0.992 -0.532
ENSG00000101337 E016 22.3323568 6.559455e-04 3.383066e-01 6.608288e-01 20 32145091 32145209 119 + 1.377 1.315 -0.215
ENSG00000101337 E017 22.7777434 5.933696e-04 1.870718e-01 5.013005e-01 20 32145312 32145423 112 + 1.393 1.308 -0.295
ENSG00000101337 E018 18.8787838 7.589738e-04 3.785388e-01 6.958099e-01 20 32146785 32146855 71 + 1.307 1.246 -0.215
ENSG00000101337 E019 30.3669418 1.371285e-03 3.480311e-01 6.687993e-01 20 32149634 32149766 133 + 1.502 1.449 -0.183
ENSG00000101337 E020 20.3749193 9.895901e-04 1.584621e-01 4.607355e-01 20 32150622 32150703 82 + 1.350 1.254 -0.337
ENSG00000101337 E021 26.1775680 7.549546e-04 3.788161e-01 6.958934e-01 20 32150800 32150875 76 + 1.440 1.387 -0.182
ENSG00000101337 E022 30.9956189 4.867668e-04 5.197626e-01 7.923760e-01 20 32155103 32155186 84 + 1.505 1.469 -0.121
ENSG00000101337 E023 49.1306360 5.384544e-04 2.464641e-01 5.730462e-01 20 32157794 32157969 176 + 1.705 1.654 -0.174
ENSG00000101337 E024 25.9916942 2.565012e-03 5.883722e-01 8.317614e-01 20 32158451 32158514 64 + 1.405 1.438 0.115
ENSG00000101337 E025 2.5036706 1.336732e-01 3.313349e-02 1.953624e-01 20 32159143 32159991 849 + 0.350 0.733 1.831
ENSG00000101337 E026 31.2119938 4.336399e-04 3.862152e-01 7.009313e-01 20 32159992 32160111 120 + 1.512 1.464 -0.163
ENSG00000101337 E027 0.3766167 1.687405e-02 2.599367e-01   20 32161093 32161275 183 + 0.071 0.225 1.938
ENSG00000101337 E028 29.9536074 5.148801e-04 2.542110e-02 1.674040e-01 20 32161276 32161365 90 + 1.521 1.393 -0.441
ENSG00000101337 E029 343.7762424 7.500234e-05 3.021100e-12 4.369976e-10 20 32165295 32167258 1964 + 2.488 2.577 0.296

Help

Please Click HERE to learn more details about the results from DEXseq.