ENSG00000101445

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000299824 ENSG00000101445 No_inf pgwt_inf PPP1R16B protein_coding protein_coding 25.01169 17.32725 30.32275 0.7025229 0.3264754 0.8070015 8.849091 0.8255121 19.124817 0.8255121 2.536388 4.51739555 0.3048083 0.042975 0.631875 0.58890 0.02570796 0.02570796 FALSE TRUE
ENST00000373331 ENSG00000101445 No_inf pgwt_inf PPP1R16B protein_coding protein_coding 25.01169 17.32725 30.32275 0.7025229 0.3264754 0.8070015 9.228859 7.9180026 8.474416 0.5375355 1.480834 0.09785793 0.3853417 0.460375 0.280625 -0.17975 0.96969959 0.02570796 FALSE TRUE
MSTRG.18274.1 ENSG00000101445 No_inf pgwt_inf PPP1R16B protein_coding   25.01169 17.32725 30.32275 0.7025229 0.3264754 0.8070015 1.387519 0.2157864 0.000000 0.2157864 0.000000 -4.49688659 0.0523250 0.013550 0.000000 -0.01355 0.99284725 0.02570796 FALSE TRUE
MSTRG.18274.3 ENSG00000101445 No_inf pgwt_inf PPP1R16B protein_coding   25.01169 17.32725 30.32275 0.7025229 0.3264754 0.8070015 5.405768 7.9465763 2.723517 1.2073347 2.723517 -1.54138955 0.2502000 0.461150 0.087500 -0.37365 0.14889981 0.02570796 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000101445 E001 0.0000000       20 38805671 38805696 26 +      
ENSG00000101445 E002 0.3591300 0.016642922 1.0000000000   20 38805697 38805710 14 + 0.126 0.132 0.072
ENSG00000101445 E003 0.6047420 0.014514985 0.8475434641   20 38805711 38805723 13 + 0.178 0.233 0.487
ENSG00000101445 E004 2.3047040 0.006133874 0.5764832899 0.825047955 20 38805724 38805792 69 + 0.456 0.584 0.612
ENSG00000101445 E005 12.7771017 0.006499971 0.3072185822 0.633556276 20 38835825 38836115 291 + 1.130 1.104 -0.093
ENSG00000101445 E006 7.0610875 0.003726742 0.5675834992 0.819616387 20 38836116 38836175 60 + 0.890 0.889 -0.002
ENSG00000101445 E007 0.1311489 0.012240249 0.2898105528   20 38838113 38838198 86 + 0.000 0.132 11.368
ENSG00000101445 E008 0.0000000       20 38838448 38838510 63 +      
ENSG00000101445 E009 8.1874910 0.003532051 0.0905059368 0.345333274 20 38889595 38889665 71 + 0.983 0.869 -0.431
ENSG00000101445 E010 10.4756788 0.002386868 0.1464781740 0.442583799 20 38895565 38895710 146 + 1.066 0.994 -0.262
ENSG00000101445 E011 9.9942106 0.001479261 0.0015646211 0.025206824 20 38900581 38900684 104 + 1.096 0.847 -0.928
ENSG00000101445 E012 11.8559501 0.001121423 0.0001888635 0.004892863 20 38902668 38902792 125 + 1.172 0.889 -1.038
ENSG00000101445 E013 10.4199472 0.001343035 0.0305930423 0.186759688 20 38905969 38906094 126 + 1.084 0.945 -0.513
ENSG00000101445 E014 8.8049347 0.001577911 0.1773314283 0.488648648 20 38906979 38907054 76 + 0.998 0.927 -0.264
ENSG00000101445 E015 14.7557256 0.001041486 0.6999727878 0.886719208 20 38907806 38907935 130 + 1.167 1.202 0.124
ENSG00000101445 E016 5.5058842 0.002869599 0.6524276118 0.864098062 20 38908028 38908031 4 + 0.795 0.801 0.024
ENSG00000101445 E017 19.2237175 0.034257686 0.4233815725 0.728616532 20 38908032 38908193 162 + 1.295 1.273 -0.079
ENSG00000101445 E018 693.9825551 0.009540132 0.0011402404 0.019811276 20 38918157 38923024 4868 + 2.787 2.881 0.312

Help

Please Click HERE to learn more details about the results from DEXseq.