ENSG00000102858

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262370 ENSG00000102858 No_inf pgwt_inf MGRN1 protein_coding protein_coding 27.43597 24.53469 32.29485 1.278454 2.542473 0.3963399 10.9925171 10.5246245 8.623132 1.1518015 1.234656 -0.2871829 0.42803333 0.431475 0.281175 -0.150300 9.928472e-01 2.29493e-06 FALSE TRUE
ENST00000586183 ENSG00000102858 No_inf pgwt_inf MGRN1 protein_coding protein_coding 27.43597 24.53469 32.29485 1.278454 2.542473 0.3963399 1.6372110 0.0000000 3.342760 0.0000000 1.043028 8.3892056 0.05621667 0.000000 0.103325 0.103325 1.235327e-02 2.29493e-06 FALSE TRUE
ENST00000588994 ENSG00000102858 No_inf pgwt_inf MGRN1 protein_coding protein_coding 27.43597 24.53469 32.29485 1.278454 2.542473 0.3963399 0.8529143 1.1011865 0.000000 1.1011865 0.000000 -6.7959571 0.04094167 0.051350 0.000000 -0.051350 9.928472e-01 2.29493e-06 FALSE TRUE
ENST00000590790 ENSG00000102858 No_inf pgwt_inf MGRN1 protein_coding protein_coding 27.43597 24.53469 32.29485 1.278454 2.542473 0.3963399 2.1384753 0.6919733 3.708993 0.6919733 2.490253 2.4054240 0.06702500 0.025300 0.107500 0.082200 9.569145e-01 2.29493e-06 FALSE TRUE
MSTRG.10565.18 ENSG00000102858 No_inf pgwt_inf MGRN1 protein_coding   27.43597 24.53469 32.29485 1.278454 2.542473 0.3963399 3.3228727 0.0000000 9.968618 0.0000000 1.357354 9.9626962 0.10308333 0.000000 0.309250 0.309250 2.294930e-06 2.29493e-06 FALSE TRUE
MSTRG.10565.21 ENSG00000102858 No_inf pgwt_inf MGRN1 protein_coding   27.43597 24.53469 32.29485 1.278454 2.542473 0.3963399 3.2428930 6.5929188 0.000000 2.4557739 0.000000 -9.3669601 0.11940833 0.255375 0.000000 -0.255375 1.468518e-01 2.29493e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000102858 E001 0.0000000       16 4616493 4616575 83 +      
ENSG00000102858 E002 0.8329479 0.0153497703 0.32261130 0.64713341 16 4624824 4624825 2 + 0.334 0.181 -1.163
ENSG00000102858 E003 2.2889516 0.0061908028 0.37178772 0.68995045 16 4624826 4624841 16 + 0.578 0.449 -0.619
ENSG00000102858 E004 2.2889516 0.0061908028 0.37178772 0.68995045 16 4624842 4624845 4 + 0.578 0.449 -0.619
ENSG00000102858 E005 3.4201838 0.0049109357 0.94243654 0.98542813 16 4624846 4624867 22 + 0.651 0.640 -0.047
ENSG00000102858 E006 5.1377182 0.0541184746 0.98663567 0.99968565 16 4624868 4624960 93 + 0.785 0.791 0.022
ENSG00000102858 E007 1.8334529 0.0572533899 0.95487830 0.98892079 16 4624961 4624986 26 + 0.455 0.449 -0.033
ENSG00000102858 E008 5.4899737 0.0291496115 0.10186598 0.36790696 16 4624987 4625048 62 + 0.694 0.902 0.826
ENSG00000102858 E009 0.8676210 0.0137422271 0.59915903 0.83724549 16 4649080 4650364 1285 + 0.229 0.309 0.574
ENSG00000102858 E010 5.5064323 0.0207463175 0.04552127 0.23456674 16 4650365 4650386 22 + 0.673 0.916 0.966
ENSG00000102858 E011 4.5682784 0.0045252852 0.40706482 0.71639846 16 4650387 4650399 13 + 0.694 0.791 0.393
ENSG00000102858 E012 11.5118184 0.0037580660 0.09971207 0.36421956 16 4650400 4650483 84 + 1.021 1.160 0.502
ENSG00000102858 E013 0.9018761 0.0215866385 0.03658617 0.20777924 16 4650484 4651106 623 + 0.091 0.407 2.744
ENSG00000102858 E014 11.2743261 0.0091164183 0.74747098 0.90955578 16 4651963 4652051 89 + 1.075 1.102 0.096
ENSG00000102858 E015 16.4155511 0.0009080037 0.03674994 0.20820780 16 4652678 4652824 147 + 1.311 1.160 -0.533
ENSG00000102858 E016 11.3179385 0.0216195237 0.64490587 0.85969241 16 4657246 4657311 66 + 1.116 1.065 -0.184
ENSG00000102858 E017 7.6540438 0.0019503477 0.49965136 0.78040756 16 4657312 4657363 52 + 0.970 0.902 -0.256
ENSG00000102858 E018 0.2279004 0.2509703678 0.34097605   16 4664069 4664286 218 + 0.165 0.000 -10.939
ENSG00000102858 E019 1.2099969 0.0588619749 0.66870906 0.87150687 16 4664416 4664708 293 + 0.378 0.309 -0.426
ENSG00000102858 E020 12.0420956 0.0011185777 0.44124303 0.74146825 16 4664709 4664775 67 + 1.084 1.144 0.218
ENSG00000102858 E021 0.7188262 0.0144324415 0.49756009 0.77885987 16 4665099 4665101 3 + 0.285 0.181 -0.841
ENSG00000102858 E022 11.2344096 0.0028586543 0.94220457 0.98537967 16 4665102 4665151 50 + 1.092 1.084 -0.029
ENSG00000102858 E023 9.2524012 0.0290389865 0.71540277 0.89452307 16 4668265 4668296 32 + 1.031 0.991 -0.146
ENSG00000102858 E024 6.9844245 0.0021485600 0.76419991 0.91645164 16 4668297 4668312 16 + 0.888 0.916 0.108
ENSG00000102858 E025 0.2454580 0.0160933230 0.92878993   16 4669121 4669252 132 + 0.091 0.100 0.159
ENSG00000102858 E026 8.6250153 0.0111652435 0.37291254 0.69080627 16 4671391 4671404 14 + 0.937 1.024 0.324
ENSG00000102858 E027 12.6494736 0.0059745531 0.51748698 0.79117998 16 4671405 4671459 55 + 1.108 1.160 0.187
ENSG00000102858 E028 0.3763283 0.0168449565 0.51493308   16 4672400 4672516 117 + 0.091 0.181 1.159
ENSG00000102858 E029 26.5203808 0.0172522849 0.98879841 1.00000000 16 4673498 4673657 160 + 1.442 1.438 -0.014
ENSG00000102858 E030 0.4571707 0.0159786997 0.05868873   16 4676406 4676452 47 + 0.285 0.000 -12.448
ENSG00000102858 E031 1.1141048 0.0185172048 0.61842448 0.84663014 16 4676921 4677462 542 + 0.285 0.360 0.481
ENSG00000102858 E032 18.1597777 0.0007727368 0.00468712 0.05570518 16 4677463 4677572 110 + 1.371 1.175 -0.686
ENSG00000102858 E033 13.5528971 0.0010848859 0.14028184 0.43350577 16 4680032 4680097 66 + 1.218 1.102 -0.415
ENSG00000102858 E034 0.7386231 0.4321472210 0.79649459 0.93003815 16 4680173 4680275 103 + 0.229 0.250 0.158
ENSG00000102858 E035 1.9657344 0.0642883430 0.85295668 0.95200173 16 4680428 4680650 223 + 0.455 0.487 0.159
ENSG00000102858 E036 0.9997828 0.0132656295 0.38842768 0.70222663 16 4680651 4680676 26 + 0.229 0.360 0.896
ENSG00000102858 E037 1.1132401 0.0130081168 0.61705169 0.84604262 16 4681348 4681549 202 + 0.285 0.360 0.481
ENSG00000102858 E038 30.8027474 0.0005885522 0.97423999 0.99548812 16 4681550 4681776 227 + 1.503 1.502 -0.001
ENSG00000102858 E039 16.7312655 0.0648677584 0.34637920 0.66746112 16 4682823 4682946 124 + 1.296 1.197 -0.348
ENSG00000102858 E040 12.0177078 0.0223389331 0.44010506 0.74081754 16 4683224 4683269 46 + 1.152 1.074 -0.282
ENSG00000102858 E041 16.1580428 0.0075082894 0.77199485 0.92045006 16 4683843 4683932 90 + 1.224 1.244 0.071
ENSG00000102858 E042 2.0260775 0.0071553070 0.14139528 0.43483831 16 4686259 4686303 45 + 0.578 0.360 -1.104
ENSG00000102858 E043 19.6219031 0.0007310538 0.07796863 0.31856180 16 4686304 4688795 2492 + 1.253 1.366 0.395
ENSG00000102858 E044 267.2421138 0.0000813116 0.51390750 0.78918377 16 4688796 4690974 2179 + 2.425 2.432 0.023

Help

Please Click HERE to learn more details about the results from DEXseq.