ENSG00000103064

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000219343 ENSG00000103064 No_inf pgwt_inf SLC7A6 protein_coding protein_coding 15.47511 15.33431 14.92196 0.4400985 0.614608 -0.03930065 4.8951941 2.688053 6.946695 1.6026325 2.3586135 1.3664833 0.32665833 0.178825 0.469350 0.290525 0.9928472467 0.0007108592 FALSE TRUE
ENST00000563208 ENSG00000103064 No_inf pgwt_inf SLC7A6 protein_coding retained_intron 15.47511 15.33431 14.92196 0.4400985 0.614608 -0.03930065 1.2920608 2.728010 0.000000 0.3349315 0.0000000 -8.0969837 0.08128333 0.176550 0.000000 -0.176550 0.0007108592 0.0007108592 FALSE FALSE
ENST00000566454 ENSG00000103064 No_inf pgwt_inf SLC7A6 protein_coding protein_coding 15.47511 15.33431 14.92196 0.4400985 0.614608 -0.03930065 2.8146868 2.475251 2.260251 2.4752514 2.0231151 -0.1305400 0.17915833 0.153650 0.148200 -0.005450 0.9928472467 0.0007108592 FALSE TRUE
ENST00000568088 ENSG00000103064 No_inf pgwt_inf SLC7A6 protein_coding protein_coding 15.47511 15.33431 14.92196 0.4400985 0.614608 -0.03930065 0.9339299 0.000000 1.101696 0.0000000 0.6386155 6.7966188 0.05382500 0.000000 0.069650 0.069650 0.9606631404 0.0007108592 FALSE FALSE
ENST00000618043 ENSG00000103064 No_inf pgwt_inf SLC7A6 protein_coding protein_coding 15.47511 15.33431 14.92196 0.4400985 0.614608 -0.03930065 1.5985149 3.788765 0.000000 1.7703486 0.0000000 -8.5693868 0.10228333 0.249975 0.000000 -0.249975 0.2981019096 0.0007108592 FALSE TRUE
ENST00000648130 ENSG00000103064 No_inf pgwt_inf SLC7A6 protein_coding nonsense_mediated_decay 15.47511 15.33431 14.92196 0.4400985 0.614608 -0.03930065 1.6662788 2.152134 1.657677 1.0438793 0.9572159 -0.3746153 0.11380000 0.142325 0.111925 -0.030400 0.9928472467 0.0007108592 TRUE TRUE
MSTRG.11419.13 ENSG00000103064 No_inf pgwt_inf SLC7A6 protein_coding   15.47511 15.33431 14.92196 0.4400985 0.614608 -0.03930065 1.4010710 1.305277 1.856562 0.7762360 1.1423364 0.5050172 0.08838333 0.085000 0.123925 0.038925 1.0000000000 0.0007108592 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000103064 E001 0.1308632 0.0122708866 0.4767853539   16 68264516 68264522 7 + 0.000 0.101 10.608
ENSG00000103064 E002 0.1308632 0.0122708866 0.4767853539   16 68264523 68264525 3 + 0.000 0.101 12.863
ENSG00000103064 E003 0.1308632 0.0122708866 0.4767853539   16 68264526 68264547 22 + 0.000 0.101 12.863
ENSG00000103064 E004 0.1308632 0.0122708866 0.4767853539   16 68264548 68264549 2 + 0.000 0.101 12.863
ENSG00000103064 E005 0.3587636 0.1515414742 0.6898514099   16 68264550 68264559 10 + 0.163 0.101 -0.794
ENSG00000103064 E006 0.5871644 0.0151672947 0.2179848639   16 68264560 68264568 9 + 0.281 0.101 -1.794
ENSG00000103064 E007 0.9293205 0.0119491780 0.0390909340 0.21587239 16 68264569 68264576 8 + 0.414 0.101 -2.602
ENSG00000103064 E008 0.1145948 0.0112957921 0.6062227130   16 68264577 68264581 5 + 0.089 0.000 -13.389
ENSG00000103064 E009 0.2457437 0.0163598352 0.9250101164   16 68264582 68264741 160 + 0.089 0.101 0.206
ENSG00000103064 E010 0.1141751 0.0113634115 0.6061103486   16 68265516 68265773 258 + 0.089 0.000 -13.389
ENSG00000103064 E011 0.0000000       16 68266591 68266592 2 +      
ENSG00000103064 E012 1.3237931 0.0097267657 0.4798710265 0.76748714 16 68266593 68266594 2 + 0.414 0.312 -0.602
ENSG00000103064 E013 1.4379682 0.0095098200 0.3410662969 0.66306861 16 68266595 68266601 7 + 0.451 0.312 -0.794
ENSG00000103064 E014 1.8957028 0.0075591256 0.0723064443 0.30550907 16 68266602 68266603 2 + 0.572 0.312 -1.379
ENSG00000103064 E015 5.8653875 0.0025173805 0.0416150673 0.22379021 16 68266604 68266721 118 + 0.931 0.717 -0.839
ENSG00000103064 E016 0.0000000       16 68272979 68273044 66 +      
ENSG00000103064 E017 0.3766167 0.0166820448 0.5112220317   16 68273795 68273817 23 + 0.089 0.184 1.206
ENSG00000103064 E018 1.2274582 0.0114684750 0.8482889866 0.95018820 16 68273818 68273821 4 + 0.330 0.364 0.206
ENSG00000103064 E019 3.1910345 0.0469783479 0.7673509110 0.91794377 16 68273822 68273904 83 + 0.598 0.645 0.206
ENSG00000103064 E020 11.5894583 0.0013908456 0.0900068543 0.34434303 16 68274691 68274868 178 + 1.160 1.031 -0.467
ENSG00000103064 E021 3.7782293 0.0120972463 0.8447441927 0.94868001 16 68274869 68274876 8 + 0.688 0.670 -0.074
ENSG00000103064 E022 13.8669476 0.0014020078 0.0340398413 0.19861516 16 68274877 68275126 250 + 1.241 1.090 -0.538
ENSG00000103064 E023 9.3553709 0.0016891009 0.4625969763 0.75614814 16 68275127 68275249 123 + 1.043 0.986 -0.209
ENSG00000103064 E024 0.5248228 0.0160315540 0.0337494978   16 68286578 68286637 60 + 0.000 0.312 14.623
ENSG00000103064 E025 1.6545379 0.1311012100 0.0636922667 0.28483127 16 68287323 68287435 113 + 0.226 0.560 1.943
ENSG00000103064 E026 3.5486681 0.0045041424 0.8897473831 0.96603120 16 68287746 68287759 14 + 0.645 0.670 0.106
ENSG00000103064 E027 6.0193743 0.0058789984 0.5753730428 0.82468485 16 68287760 68287871 112 + 0.811 0.879 0.265
ENSG00000103064 E028 0.0000000       16 68290396 68290540 145 +      
ENSG00000103064 E029 0.0000000       16 68290962 68291208 247 +      
ENSG00000103064 E030 0.0000000       16 68291209 68291285 77 +      
ENSG00000103064 E031 0.0000000       16 68291286 68291332 47 +      
ENSG00000103064 E032 0.0000000       16 68291333 68291557 225 +      
ENSG00000103064 E033 0.0000000       16 68291558 68291661 104 +      
ENSG00000103064 E034 0.0000000       16 68294678 68294704 27 +      
ENSG00000103064 E035 6.5329829 0.0073406389 0.4114796476 0.71996732 16 68294705 68294801 97 + 0.826 0.922 0.369
ENSG00000103064 E036 0.0000000       16 68294802 68294907 106 +      
ENSG00000103064 E037 14.9168261 0.0009938463 0.2053152334 0.52504285 16 68296364 68296513 150 + 1.241 1.159 -0.292
ENSG00000103064 E038 19.6201700 0.0007252204 0.0952669758 0.35505074 16 68296627 68296810 184 + 1.360 1.264 -0.335
ENSG00000103064 E039 18.0247045 0.0008321458 0.4997828164 0.78040777 16 68297234 68297476 243 + 1.252 1.305 0.186
ENSG00000103064 E040 26.5842779 0.0005780199 0.0944342697 0.35331155 16 68297477 68298490 1014 + 1.389 1.487 0.339
ENSG00000103064 E041 29.9302459 0.0070301188 0.0007362813 0.01421317 16 68298491 68301823 3333 + 1.377 1.581 0.701

Help

Please Click HERE to learn more details about the results from DEXseq.