ENSG00000103091

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000562371 ENSG00000103091 No_inf pgwt_inf WDR59 protein_coding retained_intron 16.73386 14.24457 17.25475 1.413977 2.622424 0.2764052 0.5450821 0.0000000 1.6352462 0.0000000 1.6352462 7.3621597 0.02646667 0.000000 0.079400 0.079400 0.99284725 0.02273295 FALSE FALSE
ENST00000563111 ENSG00000103091 No_inf pgwt_inf WDR59 protein_coding protein_coding 16.73386 14.24457 17.25475 1.413977 2.622424 0.2764052 0.4391064 0.5588778 0.0000000 0.5588778 0.0000000 -5.8300469 0.04116667 0.053825 0.000000 -0.053825 0.99284725 0.02273295 FALSE FALSE
ENST00000563797 ENSG00000103091 No_inf pgwt_inf WDR59 protein_coding protein_coding 16.73386 14.24457 17.25475 1.413977 2.622424 0.2764052 2.1234865 2.3415405 3.3666806 0.9659225 0.6861177 0.5219996 0.12607500 0.155525 0.197550 0.042025 0.99284725 0.02273295 FALSE FALSE
ENST00000569183 ENSG00000103091 No_inf pgwt_inf WDR59 protein_coding retained_intron 16.73386 14.24457 17.25475 1.413977 2.622424 0.2764052 0.9830621 1.8636751 0.5050455 0.9353274 0.3455989 -1.8630990 0.06380833 0.124650 0.042050 -0.082600 0.99284725 0.02273295   FALSE
ENST00000569421 ENSG00000103091 No_inf pgwt_inf WDR59 protein_coding protein_coding_CDS_not_defined 16.73386 14.24457 17.25475 1.413977 2.622424 0.2764052 1.0140701 1.5247870 0.0000000 0.5373002 0.0000000 -7.2618946 0.06689167 0.101425 0.000000 -0.101425 0.02273295 0.02273295 FALSE FALSE
ENST00000570070 ENSG00000103091 No_inf pgwt_inf WDR59 protein_coding retained_intron 16.73386 14.24457 17.25475 1.413977 2.622424 0.2764052 0.9563528 0.8814597 1.0987643 0.8814597 1.0987643 0.3147113 0.05405833 0.056000 0.053350 -0.002650 1.00000000 0.02273295 FALSE FALSE
ENST00000616369 ENSG00000103091 No_inf pgwt_inf WDR59 protein_coding protein_coding 16.73386 14.24457 17.25475 1.413977 2.622424 0.2764052 1.7015247 0.6813870 2.5024225 0.6813870 0.4033204 1.8615138 0.10483333 0.048625 0.150075 0.101450 0.54518299 0.02273295 FALSE TRUE
MSTRG.11528.2 ENSG00000103091 No_inf pgwt_inf WDR59 protein_coding   16.73386 14.24457 17.25475 1.413977 2.622424 0.2764052 3.0521821 3.4284872 2.9610619 0.3189789 0.3110153 -0.2107953 0.20237500 0.256950 0.176275 -0.080675 0.99284725 0.02273295 TRUE TRUE
MSTRG.11528.26 ENSG00000103091 No_inf pgwt_inf WDR59 protein_coding   16.73386 14.24457 17.25475 1.413977 2.622424 0.2764052 2.0130276 0.0000000 2.1919429 0.0000000 2.1919429 7.7826332 0.08861667 0.000000 0.099600 0.099600 0.99284725 0.02273295   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000103091 E001 0.2448134 0.0165993570 0.95151017   16 74871362 74871877 516 - 0.098 0.092 -0.091
ENSG00000103091 E002 24.6703427 0.0007050517 0.64964291 0.86232357 16 74871878 74874078 2201 - 1.389 1.421 0.111
ENSG00000103091 E003 19.3123582 0.0009752871 0.25300162 0.58008870 16 74874079 74874394 316 - 1.260 1.340 0.281
ENSG00000103091 E004 5.1732861 0.0039090460 0.95238529 0.98835527 16 74874395 74874425 31 - 0.782 0.794 0.046
ENSG00000103091 E005 4.6007752 0.0195016878 0.39005558 0.70369874 16 74874426 74874444 19 - 0.680 0.794 0.461
ENSG00000103091 E006 9.9898293 0.0013395512 0.05514551 0.26257550 16 74885653 74885795 143 - 0.934 1.109 0.646
ENSG00000103091 E007 0.0000000       16 74885796 74886235 440 -      
ENSG00000103091 E008 11.5616679 0.0012209181 0.15905643 0.46150058 16 74886270 74886396 127 - 1.025 1.148 0.442
ENSG00000103091 E009 0.0000000       16 74886397 74886469 73 -      
ENSG00000103091 E010 8.2059935 0.0018750212 0.24278183 0.56900437 16 74887683 74887755 73 - 0.893 1.011 0.439
ENSG00000103091 E011 5.2402953 0.0817790985 0.34684384 0.66785997 16 74888169 74888210 42 - 0.703 0.855 0.609
ENSG00000103091 E012 4.7479158 0.0392317973 0.24542599 0.57191011 16 74888211 74888243 33 - 0.657 0.826 0.686
ENSG00000103091 E013 5.9918594 0.0351090915 0.22900285 0.55427189 16 74888244 74888319 76 - 0.744 0.909 0.645
ENSG00000103091 E014 0.0000000       16 74889660 74889702 43 -      
ENSG00000103091 E015 2.9627626 0.2166598298 0.93913098 0.98390975 16 74889703 74889722 20 - 0.577 0.611 0.150
ENSG00000103091 E016 5.6615948 0.0699857582 0.93337585 0.98144417 16 74889723 74889815 93 - 0.817 0.826 0.034
ENSG00000103091 E017 6.7230010 0.0281822247 0.57694352 0.82521492 16 74892484 74892565 82 - 0.921 0.855 -0.249
ENSG00000103091 E018 5.1721120 0.0955574560 0.89862900 0.96964964 16 74893679 74893706 28 - 0.782 0.794 0.047
ENSG00000103091 E019 6.8028455 0.0084057616 0.19643451 0.51325122 16 74893707 74893812 106 - 0.958 0.826 -0.506
ENSG00000103091 E020 0.0000000       16 74893813 74893940 128 -      
ENSG00000103091 E021 0.0000000       16 74899698 74899754 57 -      
ENSG00000103091 E022 7.3386040 0.0021030275 0.01269651 0.10837869 16 74903947 74904100 154 - 1.036 0.794 -0.917
ENSG00000103091 E023 0.2446691 0.0163354785 0.95224297   16 74904101 74904346 246 - 0.098 0.092 -0.091
ENSG00000103091 E024 0.1139502 0.0113796898 0.49750458   16 74908733 74908907 175 - 0.098 0.000 -11.974
ENSG00000103091 E025 5.2324930 0.0028079650 0.31025356 0.63653255 16 74908908 74908977 70 - 0.849 0.741 -0.428
ENSG00000103091 E026 3.6988174 0.0040573482 0.87828825 0.96132979 16 74909501 74909524 24 - 0.657 0.681 0.101
ENSG00000103091 E027 8.3996086 0.0017745673 0.68219807 0.87828411 16 74909525 74909657 133 - 0.946 0.990 0.164
ENSG00000103091 E028 2.4519233 0.0319064232 0.88299602 0.96348948 16 74909658 74909746 89 - 0.547 0.528 -0.091
ENSG00000103091 E029 2.0760147 0.0267619865 0.71113134 0.89272413 16 74909747 74909821 75 - 0.515 0.462 -0.261
ENSG00000103091 E030 6.1174510 0.0027663331 0.57883046 0.82588037 16 74909822 74909917 96 - 0.879 0.826 -0.207
ENSG00000103091 E031 0.7533013 0.0270433378 0.47570487 0.76517865 16 74912005 74912117 113 - 0.178 0.290 0.909
ENSG00000103091 E032 0.8841773 0.0127621112 0.29722369 0.62496550 16 74912118 74912197 80 - 0.178 0.340 1.231
ENSG00000103091 E033 9.1111784 0.0017451071 0.10685959 0.37752884 16 74912198 74912362 165 - 1.074 0.934 -0.518
ENSG00000103091 E034 0.1308632 0.0123646646 0.58127952   16 74915460 74915679 220 - 0.000 0.092 10.992
ENSG00000103091 E035 0.0000000       16 74915680 74915717 38 -      
ENSG00000103091 E036 0.0000000       16 74915718 74915869 152 -      
ENSG00000103091 E037 5.4812200 0.0026176924 0.31626206 0.64202334 16 74915870 74915994 125 - 0.864 0.759 -0.413
ENSG00000103091 E038 0.2628107 0.0162283287 0.27017215   16 74915995 74916047 53 - 0.000 0.169 11.890
ENSG00000103091 E039 0.3771270 0.0167783081 0.63386880   16 74916048 74916126 79 - 0.098 0.169 0.909
ENSG00000103091 E040 3.4353682 0.0043997578 0.84026427 0.94707005 16 74916127 74916160 34 - 0.657 0.636 -0.091
ENSG00000103091 E041 5.6869369 0.0026802933 0.11474641 0.39150510 16 74916161 74916259 99 - 0.907 0.741 -0.651
ENSG00000103091 E042 5.6259551 0.0027753715 0.57898084 0.82594192 16 74917929 74918008 80 - 0.849 0.794 -0.217
ENSG00000103091 E043 6.5147656 0.0027456892 0.88526681 0.96411826 16 74921947 74922103 157 - 0.879 0.869 -0.037
ENSG00000103091 E044 2.8155475 0.0939120898 0.68837065 0.88101426 16 74923926 74923949 24 - 0.606 0.558 -0.216
ENSG00000103091 E045 4.3847396 0.0308022496 0.41908652 0.72545822 16 74923950 74924003 54 - 0.782 0.681 -0.413
ENSG00000103091 E046 0.0000000       16 74930768 74930792 25 -      
ENSG00000103091 E047 6.2176280 0.0024901623 0.32791930 0.65212871 16 74938150 74938250 101 - 0.907 0.810 -0.375
ENSG00000103091 E048 2.9616028 0.0695456476 0.86085203 0.95527798 16 74938251 74938266 16 - 0.577 0.611 0.150
ENSG00000103091 E049 2.4882444 0.0089974523 0.48026910 0.76782410 16 74942738 74942739 2 - 0.480 0.585 0.494
ENSG00000103091 E050 5.1362125 0.0035327856 0.57718151 0.82532681 16 74942740 74942826 87 - 0.817 0.759 -0.229
ENSG00000103091 E051 2.9103409 0.0232323498 0.34571227 0.66697491 16 74948519 74948556 38 - 0.657 0.528 -0.577
ENSG00000103091 E052 2.8310647 0.0055141309 0.98457559 0.99916231 16 74949718 74949798 81 - 0.577 0.585 0.034
ENSG00000103091 E053 0.0000000       16 74949852 74949947 96 -      
ENSG00000103091 E054 4.0944430 0.0035648903 0.51761484 0.79117998 16 74951458 74951543 86 - 0.657 0.741 0.349
ENSG00000103091 E055 2.3070226 0.0080125202 0.39962703 0.71151432 16 74956475 74956483 9 - 0.577 0.462 -0.551
ENSG00000103091 E056 3.8418781 0.0036671496 0.04676030 0.23828149 16 74956484 74956610 127 - 0.800 0.557 -1.024
ENSG00000103091 E057 0.6236085 0.0201642953 0.71955392   16 74959350 74959592 243 - 0.178 0.233 0.494
ENSG00000103091 E058 0.5082151 0.0154532031 0.35775775   16 74960703 74960744 42 - 0.098 0.233 1.494
ENSG00000103091 E059 1.1811020 0.0257675871 0.00164044 0.02614362 16 74962820 74963247 428 - 0.000 0.496 13.675
ENSG00000103091 E060 1.9466810 0.0073129836 0.51762084 0.79117998 16 74965773 74965822 50 - 0.515 0.425 -0.454
ENSG00000103091 E061 0.0000000       16 74979012 74979116 105 -      
ENSG00000103091 E062 0.1316618 0.0123904327 0.58130194   16 74984603 74984963 361 - 0.000 0.092 10.992
ENSG00000103091 E063 1.7189320 0.0087907473 0.88639189 0.96446240 16 74984964 74985123 160 - 0.442 0.425 -0.091
ENSG00000103091 E064 0.0000000       16 74996972 74997173 202 -      
ENSG00000103091 E065 0.0000000       16 75000023 75000173 151 -      

Help

Please Click HERE to learn more details about the results from DEXseq.