ENSG00000103978

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000389834 ENSG00000103978 No_inf pgwt_inf TMEM87A protein_coding protein_coding 48.18618 49.37651 45.19456 2.245341 2.412465 -0.1276486 31.142896 24.806675 34.467100 1.8960367 1.538954 0.4743286 0.66050000 0.507525 0.770725 0.263200 7.327892e-01 2.770002e-05 FALSE TRUE
ENST00000448392 ENSG00000103978 No_inf pgwt_inf TMEM87A protein_coding nonsense_mediated_decay 48.18618 49.37651 45.19456 2.245341 2.412465 -0.1276486 2.467554 4.823726 0.000000 2.1848994 0.000000 -8.9169918 0.04958333 0.099350 0.000000 -0.099350 2.854143e-01 2.770002e-05 FALSE TRUE
ENST00000568067 ENSG00000103978 No_inf pgwt_inf TMEM87A protein_coding retained_intron 48.18618 49.37651 45.19456 2.245341 2.412465 -0.1276486 5.615195 6.563049 4.138276 2.2139635 2.579696 -0.6640507 0.10560833 0.128425 0.084050 -0.044375 9.928472e-01 2.770002e-05   FALSE
MSTRG.9464.2 ENSG00000103978 No_inf pgwt_inf TMEM87A protein_coding   48.18618 49.37651 45.19456 2.245341 2.412465 -0.1276486 2.171593 6.118898 0.000000 0.8043006 0.000000 -9.2594838 0.04388333 0.125150 0.000000 -0.125150 2.770002e-05 2.770002e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000103978 E001 0.3591300 0.0167468929 5.731887e-01   15 42210447 42210527 81 - 0.174 0.095 -1.012
ENSG00000103978 E002 0.6220849 0.0205899683 6.710352e-01   15 42210528 42210531 4 - 0.174 0.238 0.573
ENSG00000103978 E003 10.2097924 0.0013973671 8.002821e-01 0.9314947371 15 42210532 42210578 47 - 1.035 1.060 0.092
ENSG00000103978 E004 11.2087820 0.0013213075 6.575654e-01 0.8663239465 15 42210579 42210591 13 - 1.063 1.104 0.146
ENSG00000103978 E005 154.8433407 0.0001243319 1.775767e-03 0.0278360566 15 42210592 42211138 547 - 2.150 2.224 0.246
ENSG00000103978 E006 133.9843711 0.0001492918 5.092799e-02 0.2504154141 15 42211139 42211749 611 - 2.101 2.152 0.171
ENSG00000103978 E007 30.1217492 0.0005282573 7.481867e-01 0.9096964033 15 42217803 42217833 31 - 1.481 1.501 0.070
ENSG00000103978 E008 0.3592640 0.0166472862 5.736492e-01   15 42217834 42218006 173 - 0.174 0.095 -1.012
ENSG00000103978 E009 41.4222670 0.0003303210 2.872997e-01 0.6150001187 15 42218323 42218375 53 - 1.598 1.650 0.177
ENSG00000103978 E010 26.7765248 0.0005523857 2.998371e-01 0.6270919367 15 42218376 42218378 3 - 1.408 1.470 0.214
ENSG00000103978 E011 48.7757538 0.0003441846 5.687809e-01 0.8204531940 15 42219581 42219639 59 - 1.707 1.686 -0.070
ENSG00000103978 E012 28.1358706 0.0033288730 1.007825e-01 0.3657966818 15 42219640 42219642 3 - 1.511 1.417 -0.326
ENSG00000103978 E013 28.0043046 0.0011009350 6.990070e-02 0.2998321525 15 42220062 42220135 74 - 1.511 1.413 -0.340
ENSG00000103978 E014 0.1308632 0.0122484716 5.471601e-01   15 42226603 42226805 203 - 0.000 0.095 11.531
ENSG00000103978 E015 0.0000000       15 42226806 42226909 104 -      
ENSG00000103978 E016 0.0000000       15 42227615 42227710 96 -      
ENSG00000103978 E017 9.5549726 0.0019601134 7.670333e-01 0.9177085847 15 42227711 42227769 59 - 1.035 1.011 -0.086
ENSG00000103978 E018 28.7566540 0.0058402880 5.209798e-01 0.7930928387 15 42228712 42228820 109 - 1.491 1.456 -0.123
ENSG00000103978 E019 21.2619113 0.0024931926 4.051734e-01 0.7150848569 15 42231192 42231260 69 - 1.373 1.322 -0.178
ENSG00000103978 E020 1.3584120 0.0096095494 7.860819e-01 0.9258777659 15 42231844 42231915 72 - 0.348 0.391 0.251
ENSG00000103978 E021 0.8853420 0.0134384375 2.630517e-01 0.5911341243 15 42232879 42233212 334 - 0.174 0.346 1.310
ENSG00000103978 E022 22.9308297 0.0006166203 2.013381e-01 0.5201339230 15 42233213 42233306 94 - 1.416 1.342 -0.258
ENSG00000103978 E023 15.2330053 0.0198684505 8.979246e-01 0.9694963111 15 42236320 42236354 35 - 1.204 1.214 0.034
ENSG00000103978 E024 19.2197739 0.0055492599 6.534587e-01 0.8646438324 15 42236355 42236419 65 - 1.320 1.291 -0.104
ENSG00000103978 E025 32.2404863 0.0005288531 2.133137e-01 0.5352567414 15 42237432 42237544 113 - 1.552 1.491 -0.209
ENSG00000103978 E026 22.2451372 0.0031371874 4.169780e-01 0.7238230292 15 42237545 42237615 71 - 1.391 1.342 -0.171
ENSG00000103978 E027 0.0000000       15 42239668 42239669 2 -      
ENSG00000103978 E028 20.5808605 0.0008208435 6.802169e-01 0.8771160969 15 42239670 42239731 62 - 1.345 1.322 -0.081
ENSG00000103978 E029 23.2753241 0.0006345395 1.369589e-01 0.4287162577 15 42244050 42244131 82 - 1.428 1.342 -0.300
ENSG00000103978 E030 13.2446006 0.0013115521 1.308225e-01 0.4196421477 15 42244132 42244167 36 - 1.211 1.095 -0.412
ENSG00000103978 E031 5.9288794 0.0049698527 6.109287e-01 0.8430383478 15 42257935 42258790 856 - 0.807 0.866 0.229
ENSG00000103978 E032 1.9618298 0.0317679632 9.728935e-01 0.9952599883 15 42258791 42258990 200 - 0.472 0.470 -0.012
ENSG00000103978 E033 17.3385371 0.0030673028 3.657323e-01 0.6845590103 15 42260958 42261002 45 - 1.294 1.233 -0.216
ENSG00000103978 E034 16.9217315 0.0107463244 8.322358e-01 0.9436757759 15 42261196 42261249 54 - 1.260 1.245 -0.054
ENSG00000103978 E035 0.1311489 0.0122713987 5.471801e-01   15 42262123 42262243 121 - 0.000 0.095 11.530
ENSG00000103978 E036 28.3492847 0.0046390237 6.677351e-02 0.2924701623 15 42264090 42264203 114 - 1.521 1.413 -0.373
ENSG00000103978 E037 25.3009707 0.0005407132 5.421988e-02 0.2602644312 15 42267947 42268032 86 - 1.474 1.365 -0.375
ENSG00000103978 E038 0.1315150 0.0122987260 5.471753e-01   15 42271555 42271601 47 - 0.000 0.095 11.530
ENSG00000103978 E039 12.9710080 0.0189055427 7.015736e-01 0.8878760407 15 42272063 42272123 61 - 1.162 1.128 -0.121
ENSG00000103978 E040 2.4620661 0.0065262714 3.126094e-04 0.0073203271 15 42272676 42272888 213 - 0.174 0.711 3.075
ENSG00000103978 E041 1.9689547 0.0072140619 1.511773e-05 0.0006102965 15 42272889 42272962 74 - 0.000 0.668 15.185
ENSG00000103978 E042 2.3638438 0.0150398696 2.619677e-06 0.0001318957 15 42272963 42273254 292 - 0.000 0.731 15.353
ENSG00000103978 E043 0.0000000       15 42273255 42273534 280 -      

Help

Please Click HERE to learn more details about the results from DEXseq.