ENSG00000104324

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000220763 ENSG00000104324 No_inf pgwt_inf CPQ protein_coding protein_coding 99.99057 68.39363 113.0034 4.533252 4.184753 0.7243491 58.495807 44.4194568 63.3740252 2.1072249 3.7458920 0.5126028 0.59998333 0.66185 0.565700 -0.096150 0.992847247 0.007926782 FALSE TRUE
MSTRG.27962.10 ENSG00000104324 No_inf pgwt_inf CPQ protein_coding   99.99057 68.39363 113.0034 4.533252 4.184753 0.7243491 9.030313 19.4513981 0.7374281 4.7971391 0.7374281 -4.7025368 0.11235833 0.27420 0.006475 -0.267725 0.007926782 0.007926782 FALSE TRUE
MSTRG.27962.11 ENSG00000104324 No_inf pgwt_inf CPQ protein_coding   99.99057 68.39363 113.0034 4.533252 4.184753 0.7243491 21.222092 1.9885592 32.0802129 1.2181937 4.3690609 4.0051012 0.18600000 0.02695 0.280825 0.253875 0.229250904 0.007926782 FALSE TRUE
MSTRG.27962.8 ENSG00000104324 No_inf pgwt_inf CPQ protein_coding   99.99057 68.39363 113.0034 4.533252 4.184753 0.7243491 3.767866 0.7305222 7.6638870 0.4987101 0.7415460 3.3733427 0.03453333 0.01095 0.067775 0.056825 0.396662257 0.007926782 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000104324 E001 7.9261531 0.0016703867 0.687974810 0.88089317 8 96645242 96645370 129 + 0.960 0.920 -0.150
ENSG00000104324 E002 5.3737563 0.0027169801 0.393682611 0.70687632 8 96645371 96645374 4 + 0.835 0.736 -0.394
ENSG00000104324 E003 10.3113294 0.0142552152 0.551858336 0.81193263 8 96645375 96645402 28 + 1.070 1.009 -0.222
ENSG00000104324 E004 0.2458369 0.0163690017 0.684611473   8 96659284 96659323 40 + 0.075 0.120 0.753
ENSG00000104324 E005 0.5702815 0.0318099597 0.079479559   8 96680443 96680547 105 + 0.288 0.000 -13.003
ENSG00000104324 E006 0.0000000       8 96732292 96732394 103 +      
ENSG00000104324 E007 0.3768390 0.0166409331 0.311298577   8 96760974 96761038 65 + 0.075 0.214 1.753
ENSG00000104324 E008 0.3592742 0.0165917504 1.000000000   8 96761039 96761079 41 + 0.139 0.120 -0.247
ENSG00000104324 E009 3.3622647 0.0042296394 0.001105337 0.01937844 8 96761240 96761492 253 + 0.771 0.291 -2.363
ENSG00000104324 E010 133.3657183 0.0023840191 0.863548984 0.95646396 8 96784864 96785330 467 + 2.123 2.117 -0.018
ENSG00000104324 E011 81.7433560 0.0008711315 0.695246517 0.88426429 8 96834973 96835180 208 + 1.915 1.902 -0.044
ENSG00000104324 E012 109.0928222 0.0001609069 0.354961588 0.67505520 8 96879798 96880005 208 + 2.044 2.018 -0.088
ENSG00000104324 E013 81.8869300 0.0004935949 0.734682699 0.90351497 8 96965935 96966046 112 + 1.915 1.904 -0.039
ENSG00000104324 E014 0.6562574 0.3028799059 0.023456980 0.15907476 8 96989302 96989363 62 + 0.000 0.413 14.306
ENSG00000104324 E015 2.2012240 0.0563406665 0.016971317 0.13048177 8 96989507 96989604 98 + 0.624 0.214 -2.334
ENSG00000104324 E016 74.2666057 0.0002212242 0.497690401 0.77898167 8 97029403 97029468 66 + 1.859 1.883 0.079
ENSG00000104324 E017 51.3433363 0.0002804543 0.472646111 0.76289615 8 97029469 97029494 26 + 1.723 1.693 -0.102
ENSG00000104324 E018 3.3019103 0.0128579365 0.081789409 0.32712066 8 97055527 97055645 119 + 0.712 0.463 -1.122
ENSG00000104324 E019 0.5243902 0.0159470146 0.011836778   8 97056406 97056545 140 + 0.000 0.356 13.984
ENSG00000104324 E020 132.4527913 0.0001535975 0.657190707 0.86619731 8 97066009 97066210 202 + 2.122 2.111 -0.037
ENSG00000104324 E021 1.3925015 0.0101107274 0.018432421 0.13751785 8 97092362 97092936 575 + 0.195 0.549 2.168
ENSG00000104324 E022 111.7037926 0.0001896423 0.139095356 0.43193269 8 97143020 97143188 169 + 2.027 2.068 0.138
ENSG00000104324 E023 122.7877214 0.0001518288 0.065400445 0.28905570 8 97143189 97143501 313 + 2.065 2.113 0.162
ENSG00000104324 E024 0.2285450 0.0154017987 0.480611453   8 97149586 97149654 69 + 0.139 0.000 -11.681

Help

Please Click HERE to learn more details about the results from DEXseq.