ENSG00000104894

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000426897 ENSG00000104894 No_inf pgwt_inf CD37 protein_coding protein_coding 174.6595 277.8164 117.6815 2.260878 1.924567 -1.239174 60.42372 85.03714 51.18579 7.957460 6.192302 -0.7322376 0.36419167 0.305700 0.433625 0.127925 9.928472e-01 8.870791e-08 FALSE TRUE
ENST00000595725 ENSG00000104894 No_inf pgwt_inf CD37 protein_coding nonsense_mediated_decay 174.6595 277.8164 117.6815 2.260878 1.924567 -1.239174 76.41141 116.10598 54.37790 5.680897 5.197666 -1.0942087 0.44613333 0.418175 0.462950 0.044775 9.938822e-01 8.870791e-08 FALSE TRUE
ENST00000596426 ENSG00000104894 No_inf pgwt_inf CD37 protein_coding protein_coding_CDS_not_defined 174.6595 277.8164 117.6815 2.260878 1.924567 -1.239174 15.41829 35.12228 0.00000 3.847651 0.000000 -11.7785813 0.07019167 0.126500 0.000000 -0.126500 8.870791e-08 8.870791e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000104894 E001 0.2625250 1.607845e-02 7.088087e-01   19 49335171 49335204 34 + 0.000 0.121 9.555
ENSG00000104894 E002 0.5250500 6.770410e-02 2.484763e-01   19 49335205 49335293 89 + 0.000 0.216 12.061
ENSG00000104894 E003 0.0000000       19 49335294 49335322 29 +      
ENSG00000104894 E004 0.1311489 1.224162e-02 1.000000e+00   19 49335396 49335399 4 + 0.000 0.065 10.550
ENSG00000104894 E005 0.3939596 2.677788e-02 3.973247e-01   19 49335400 49335405 6 + 0.000 0.171 11.940
ENSG00000104894 E006 2.0326104 7.208467e-03 6.438072e-01 8.594655e-01 19 49335406 49335417 12 + 0.395 0.468 0.382
ENSG00000104894 E007 8.6059811 1.897199e-02 7.252976e-01 8.993612e-01 19 49335418 49335426 9 + 0.906 0.950 0.164
ENSG00000104894 E008 9.4895896 3.851020e-03 6.742514e-01 8.741304e-01 19 49335427 49335433 7 + 0.945 0.987 0.160
ENSG00000104894 E009 16.3874956 1.249812e-02 9.033011e-01 9.714609e-01 19 49335434 49335445 12 + 1.200 1.191 -0.033
ENSG00000104894 E010 25.4784751 1.728768e-03 9.797599e-01 9.974214e-01 19 49335446 49335456 11 + 1.374 1.376 0.006
ENSG00000104894 E011 30.5759515 4.913788e-04 6.462450e-01 8.603742e-01 19 49335457 49335463 7 + 1.431 1.459 0.094
ENSG00000104894 E012 60.4717264 2.442151e-04 7.152555e-01 8.944232e-01 19 49335464 49335494 31 + 1.751 1.736 -0.051
ENSG00000104894 E013 112.9065182 9.372320e-04 3.892436e-01 7.028044e-01 19 49335495 49335575 81 + 2.027 2.000 -0.093
ENSG00000104894 E014 72.4797389 6.190038e-04 6.004236e-01 8.378437e-01 19 49335576 49335609 34 + 1.802 1.823 0.070
ENSG00000104894 E015 3.4925576 3.860065e-02 2.946420e-02 1.822366e-01 19 49335610 49335713 104 + 0.325 0.688 1.797
ENSG00000104894 E016 106.7642986 1.392493e-04 6.922894e-01 8.829675e-01 19 49335714 49335782 69 + 1.974 1.987 0.042
ENSG00000104894 E017 53.0103472 3.225365e-03 7.530001e-01 9.117411e-01 19 49335783 49335786 4 + 1.673 1.688 0.052
ENSG00000104894 E018 2.1464089 6.507617e-03 9.385523e-01 9.837450e-01 19 49335787 49335885 99 + 0.456 0.468 0.060
ENSG00000104894 E019 4.8703531 2.962045e-03 9.844495e-02 3.617619e-01 19 49335886 49336029 144 + 0.556 0.778 0.944
ENSG00000104894 E020 28.2916090 4.924591e-04 1.435379e-04 3.939945e-03 19 49336030 49336908 879 + 1.220 1.475 0.889
ENSG00000104894 E021 157.7088370 1.181151e-03 3.508537e-01 6.712105e-01 19 49336909 49337033 125 + 2.171 2.144 -0.089
ENSG00000104894 E022 115.3993813 2.336547e-04 6.274411e-01 8.507763e-01 19 49337147 49337214 68 + 2.027 2.013 -0.049
ENSG00000104894 E023 77.2573345 2.857420e-03 7.602954e-01 9.147356e-01 19 49337215 49337221 7 + 1.834 1.849 0.049
ENSG00000104894 E024 1.1836368 1.092890e-01 4.092507e-02 2.215529e-01 19 49337222 49337246 25 + 0.000 0.390 13.034
ENSG00000104894 E025 3.3264021 4.816039e-03 2.056884e-01 5.254350e-01 19 49337626 49337924 299 + 0.456 0.642 0.867
ENSG00000104894 E026 188.0924799 8.967316e-05 6.093705e-02 2.780607e-01 19 49337925 49338029 105 + 2.258 2.215 -0.143
ENSG00000104894 E027 2.3452751 6.543112e-03 9.294058e-03 8.862662e-02 19 49338156 49338201 46 + 0.137 0.573 2.885
ENSG00000104894 E028 304.1372066 7.101074e-05 6.828658e-02 2.960926e-01 19 49338700 49338936 237 + 2.458 2.426 -0.106
ENSG00000104894 E029 87.3678186 1.740077e-04 4.601033e-01 7.543483e-01 19 49339330 49339413 84 + 1.916 1.890 -0.086
ENSG00000104894 E030 25.3196113 5.388148e-04 3.691613e-02 2.088923e-01 19 49339414 49339657 244 + 1.266 1.407 0.490
ENSG00000104894 E031 61.8305351 2.289341e-04 1.538198e-06 8.273232e-05 19 49339658 49340250 593 + 1.581 1.799 0.738
ENSG00000104894 E032 175.1491338 2.695055e-03 4.775244e-01 7.658628e-01 19 49340251 49340594 344 + 2.212 2.191 -0.072
ENSG00000104894 E033 0.0000000       19 49340595 49340860 266 +      
ENSG00000104894 E034 0.0000000       19 49343283 49343335 53 +      

Help

Please Click HERE to learn more details about the results from DEXseq.