ENSG00000105122

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000343625 ENSG00000105122 No_inf pgwt_inf RASAL3 protein_coding protein_coding 44.97122 58.35845 37.27419 1.530222 0.8648119 -0.6466247 6.882083 0.000000 9.872120 0.0000000 0.8474249 9.9486768 0.18485000 0.000000 0.265500 0.265500 2.741885e-08 2.741885e-08 FALSE TRUE
ENST00000599694 ENSG00000105122 No_inf pgwt_inf RASAL3 protein_coding protein_coding 44.97122 58.35845 37.27419 1.530222 0.8648119 -0.6466247 2.285776 1.940272 1.617459 1.9402722 1.6174594 -0.2610539 0.05042500 0.030850 0.043250 0.012400 1.000000e+00 2.741885e-08 FALSE TRUE
ENST00000609274 ENSG00000105122 No_inf pgwt_inf RASAL3 protein_coding protein_coding 44.97122 58.35845 37.27419 1.530222 0.8648119 -0.6466247 3.764351 8.278299 1.752182 0.7869075 0.8068426 -2.2337131 0.07330833 0.141325 0.048000 -0.093325 8.773646e-01 2.741885e-08 FALSE TRUE
MSTRG.14684.10 ENSG00000105122 No_inf pgwt_inf RASAL3 protein_coding   44.97122 58.35845 37.27419 1.530222 0.8648119 -0.6466247 4.106451 6.669305 1.621884 1.5844664 0.9834817 -2.0331592 0.08575833 0.115650 0.042925 -0.072725 9.463258e-01 2.741885e-08 FALSE TRUE
MSTRG.14684.5 ENSG00000105122 No_inf pgwt_inf RASAL3 protein_coding   44.97122 58.35845 37.27419 1.530222 0.8648119 -0.6466247 6.335297 10.170951 5.532887 1.4575882 0.3135388 -0.8771628 0.13533333 0.174225 0.148350 -0.025875 9.943696e-01 2.741885e-08 FALSE TRUE
MSTRG.14684.6 ENSG00000105122 No_inf pgwt_inf RASAL3 protein_coding   44.97122 58.35845 37.27419 1.530222 0.8648119 -0.6466247 4.095617 7.430194 3.236355 0.4216441 0.5112714 -1.1965194 0.08583333 0.128075 0.087625 -0.040450 9.928472e-01 2.741885e-08 FALSE TRUE
MSTRG.14684.7 ENSG00000105122 No_inf pgwt_inf RASAL3 protein_coding   44.97122 58.35845 37.27419 1.530222 0.8648119 -0.6466247 5.747008 9.152979 3.485631 1.5838792 1.4923000 -1.3902637 0.12483333 0.158450 0.094500 -0.063950 9.928472e-01 2.741885e-08 FALSE TRUE
MSTRG.14684.8 ENSG00000105122 No_inf pgwt_inf RASAL3 protein_coding   44.97122 58.35845 37.27419 1.530222 0.8648119 -0.6466247 5.696061 8.105369 6.146691 3.2946706 1.3397693 -0.3985015 0.12442500 0.138775 0.163025 0.024250 9.928472e-01 2.741885e-08 FALSE TRUE
MSTRG.14684.9 ENSG00000105122 No_inf pgwt_inf RASAL3 protein_coding   44.97122 58.35845 37.27419 1.530222 0.8648119 -0.6466247 3.446633 2.558368 1.117860 1.6793348 1.1178604 -1.1872634 0.07868333 0.044050 0.030425 -0.013625 9.928472e-01 2.741885e-08 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000105122 E001 0.2283502 0.2643780608 1.761814e-01   19 15451624 15451626 3 - 0.204 0.000 -10.807
ENSG00000105122 E002 0.7015644 0.0137940694 3.086551e-02 0.187560248 19 15451627 15451628 2 - 0.398 0.079 -2.911
ENSG00000105122 E003 3.4536780 0.0050376699 4.945592e-01 0.776752266 19 15451629 15451657 29 - 0.691 0.601 -0.383
ENSG00000105122 E004 71.2255438 0.0052908205 5.400478e-01 0.805127365 19 15451658 15451938 281 - 1.825 1.853 0.095
ENSG00000105122 E005 6.0521356 0.0024331468 2.007161e-04 0.005128734 19 15451939 15452044 106 - 0.492 0.953 1.925
ENSG00000105122 E006 36.4465282 0.0003932736 1.086362e-02 0.097979327 19 15452045 15452108 64 - 1.470 1.601 0.448
ENSG00000105122 E007 26.1648946 0.0137356882 7.605389e-06 0.000335332 19 15452109 15452657 549 - 1.153 1.520 1.282
ENSG00000105122 E008 58.5755336 0.0005561889 8.668525e-01 0.957565691 19 15452658 15452815 158 - 1.764 1.757 -0.025
ENSG00000105122 E009 107.3770537 0.0001429623 9.921361e-01 1.000000000 19 15453107 15453497 391 - 2.020 2.019 -0.003
ENSG00000105122 E010 54.7924928 0.0002514147 6.384695e-01 0.856487759 19 15454149 15454267 119 - 1.743 1.723 -0.067
ENSG00000105122 E011 46.2612484 0.0003253867 3.410736e-01 0.663068607 19 15454361 15454473 113 - 1.685 1.643 -0.145
ENSG00000105122 E012 44.7511561 0.0023994940 7.489282e-01 0.909885810 19 15454474 15454562 89 - 1.655 1.639 -0.054
ENSG00000105122 E013 1.2782116 0.1965536197 2.698174e-01 0.598013437 19 15454653 15454656 4 - 0.204 0.414 1.411
ENSG00000105122 E014 90.0080696 0.0001710914 8.170857e-01 0.937392889 19 15454657 15454893 237 - 1.939 1.946 0.022
ENSG00000105122 E015 40.3412781 0.0060227737 2.247118e-03 0.033062775 19 15454894 15456103 1210 - 1.479 1.658 0.612
ENSG00000105122 E016 40.0810720 0.0003833948 4.995316e-01 0.780320483 19 15456104 15456164 61 - 1.618 1.586 -0.112
ENSG00000105122 E017 43.0258707 0.0003320849 8.475591e-01 0.949724909 19 15456165 15456248 84 - 1.634 1.624 -0.032
ENSG00000105122 E018 9.3592679 0.0062799740 4.703904e-02 0.239205645 19 15456249 15456375 127 - 0.864 1.064 0.746
ENSG00000105122 E019 7.3368208 0.0425171067 9.045360e-01 0.971795215 19 15456376 15456501 126 - 0.914 0.902 -0.045
ENSG00000105122 E020 40.0901811 0.0003999794 4.985570e-01 0.779451740 19 15456502 15456646 145 - 1.618 1.586 -0.112
ENSG00000105122 E021 1.0172922 0.1180052878 4.376232e-01 0.739252357 19 15456647 15456679 33 - 0.204 0.342 0.996
ENSG00000105122 E022 0.5089205 0.0153289419 5.535839e-01   19 15456778 15456891 114 - 0.114 0.204 0.996
ENSG00000105122 E023 26.0787856 0.0214376089 3.338253e-01 0.657151535 19 15457292 15457468 177 - 1.466 1.386 -0.274
ENSG00000105122 E024 53.0499584 0.0075423004 3.494175e-01 0.670008170 19 15457469 15457834 366 - 1.748 1.698 -0.168
ENSG00000105122 E025 7.7019599 0.0408879633 2.031186e-01 0.522318917 19 15457835 15457921 87 - 0.807 0.982 0.667
ENSG00000105122 E026 31.5481554 0.0006394704 1.719577e-02 0.131668025 19 15457922 15458327 406 - 1.409 1.541 0.454
ENSG00000105122 E027 29.8586664 0.0113842740 1.313893e-01 0.420345994 19 15458328 15458426 99 - 1.536 1.434 -0.350
ENSG00000105122 E028 31.8460380 0.0188753970 2.205196e-01 0.544261998 19 15458529 15458655 127 - 1.558 1.464 -0.320
ENSG00000105122 E029 12.7438262 0.0248525252 5.430044e-01 0.806919927 19 15460203 15460220 18 - 1.162 1.100 -0.223
ENSG00000105122 E030 16.6509725 0.0393283902 3.707760e-01 0.689094447 19 15460221 15460258 38 - 1.293 1.192 -0.353
ENSG00000105122 E031 17.6423551 0.0107486114 8.822993e-01 0.963006400 19 15461060 15461121 62 - 1.265 1.250 -0.055
ENSG00000105122 E032 18.2207305 0.0118776014 1.357006e-01 0.426780529 19 15461218 15461296 79 - 1.343 1.219 -0.433
ENSG00000105122 E033 0.3928752 0.0279724809 2.117392e-01   19 15461297 15461317 21 - 0.000 0.204 13.163
ENSG00000105122 E034 18.9659286 0.0006830667 6.222830e-02 0.280762519 19 15461471 15461607 137 - 1.360 1.235 -0.439
ENSG00000105122 E035 31.1529803 0.0007130940 8.292110e-04 0.015505670 19 15464031 15464377 347 - 1.596 1.417 -0.612
ENSG00000105122 E036 1.9628287 0.0075377543 4.237228e-01 0.728896498 19 15464505 15464566 62 - 0.532 0.414 -0.589

Help

Please Click HERE to learn more details about the results from DEXseq.