ENSG00000105325

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000441788 ENSG00000105325 No_inf pgwt_inf FZR1 protein_coding protein_coding 15.63494 10.78143 21.14496 0.4112202 1.179508 0.9711097 9.4962627 8.5798197 10.2162586 0.1097902 0.7435841 0.2515787 0.64660000 0.79915 0.487825 -0.311325 0.4168940766 0.0008256235 FALSE TRUE
ENST00000586212 ENSG00000105325 No_inf pgwt_inf FZR1 protein_coding retained_intron 15.63494 10.78143 21.14496 0.4112202 1.179508 0.9711097 0.8177285 1.3587314 0.9138881 0.3406168 0.5580900 -0.5670493 0.06171667 0.12635 0.046125 -0.080225 0.9528329924 0.0008256235 FALSE FALSE
ENST00000588327 ENSG00000105325 No_inf pgwt_inf FZR1 protein_coding retained_intron 15.63494 10.78143 21.14496 0.4112202 1.179508 0.9711097 1.2017300 0.5180845 3.0871056 0.5180845 1.7255034 2.5520799 0.06196667 0.04375 0.142150 0.098400 0.9719252187 0.0008256235 TRUE FALSE
ENST00000592214 ENSG00000105325 No_inf pgwt_inf FZR1 protein_coding retained_intron 15.63494 10.78143 21.14496 0.4112202 1.179508 0.9711097 3.6220148 0.0000000 5.9988712 0.0000000 1.3425938 9.2309502 0.19959167 0.00000 0.278725 0.278725 0.0008256235 0.0008256235 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000105325 E001 4.8220685 0.0030483214 5.307687e-01 7.992237e-01 19 3506311 3506362 52 + 0.797 0.722 -0.302
ENSG00000105325 E002 4.4799903 0.0033004554 8.192913e-01 9.382771e-01 19 3506363 3506376 14 + 0.751 0.722 -0.117
ENSG00000105325 E003 9.0201891 0.0051585733 2.733305e-01 6.016377e-01 19 3506377 3506474 98 + 1.046 0.939 -0.395
ENSG00000105325 E004 0.3592737 0.1816564035 8.202726e-01   19 3519233 3519821 589 + 0.153 0.109 -0.564
ENSG00000105325 E005 0.1141751 0.0111572525 7.303727e-01   19 3520994 3521113 120 + 0.083 0.000 -9.093
ENSG00000105325 E006 6.2577997 0.0116897376 4.153598e-01 7.226833e-01 19 3522956 3522983 28 + 0.900 0.807 -0.361
ENSG00000105325 E007 5.1634039 0.0043233280 3.202059e-01 6.450931e-01 19 3522984 3522989 6 + 0.839 0.722 -0.465
ENSG00000105325 E008 10.8392724 0.0014572056 2.675655e-01 5.958495e-01 19 3522990 3523058 69 + 1.114 1.017 -0.353
ENSG00000105325 E009 18.9208967 0.0073689483 8.666539e-01 9.575433e-01 19 3525868 3525993 126 + 1.304 1.290 -0.050
ENSG00000105325 E010 0.2281253 0.0153488073 3.662037e-01   19 3526100 3526119 20 + 0.153 0.000 -10.023
ENSG00000105325 E011 13.1772336 0.0011930271 5.317333e-01 7.999668e-01 19 3526120 3526183 64 + 1.173 1.122 -0.183
ENSG00000105325 E012 0.3596939 0.0165538091 7.909987e-01   19 3526184 3526258 75 + 0.153 0.109 -0.565
ENSG00000105325 E013 13.5037302 0.0022833936 2.988834e-01 6.263678e-01 19 3526259 3526386 128 + 1.197 1.113 -0.302
ENSG00000105325 E014 9.5271510 0.0014888420 1.169783e-02 1.028301e-01 19 3526980 3527062 83 + 1.114 0.878 -0.874
ENSG00000105325 E015 5.5706710 0.0028689615 1.677665e-02 1.295426e-01 19 3527631 3527634 4 + 0.923 0.645 -1.109
ENSG00000105325 E016 16.5863946 0.0018992856 1.005746e-01 3.654589e-01 19 3527635 3527814 180 + 1.295 1.175 -0.426
ENSG00000105325 E017 9.7115605 0.0014724225 9.874469e-01 9.998525e-01 19 3530792 3530857 66 + 1.029 1.029 -0.001
ENSG00000105325 E018 15.6742180 0.0089780610 3.233595e-01 6.478174e-01 19 3531714 3531816 103 + 1.257 1.175 -0.290
ENSG00000105325 E019 22.7881136 0.0050875612 2.090234e-01 5.297534e-01 19 3531911 3532095 185 + 1.412 1.327 -0.297
ENSG00000105325 E020 14.2047276 0.0009815844 1.842970e-01 4.975888e-01 19 3532417 3532482 66 + 1.225 1.122 -0.367
ENSG00000105325 E021 15.5477270 0.0082514499 9.191001e-01 9.764519e-01 19 3532483 3532576 94 + 1.214 1.222 0.027
ENSG00000105325 E022 17.0794616 0.0008280062 3.821969e-02 2.128546e-01 19 3532577 3532650 74 + 1.185 1.327 0.498
ENSG00000105325 E023 18.5748235 0.0007890944 9.832975e-01 9.986305e-01 19 3533294 3533398 105 + 1.291 1.290 -0.002
ENSG00000105325 E024 1.7203655 0.1163985893 5.914964e-01 8.332236e-01 19 3533399 3533748 350 + 0.393 0.476 0.435
ENSG00000105325 E025 0.2450991 0.0161607077 8.118625e-01   19 3534285 3534420 136 + 0.083 0.109 0.435
ENSG00000105325 E026 13.8134330 0.0218483050 1.877330e-01 5.022521e-01 19 3534421 3534513 93 + 1.225 1.093 -0.472
ENSG00000105325 E027 0.7207166 0.0154960629 6.525271e-01 8.640981e-01 19 3534514 3534522 9 + 0.265 0.196 -0.565
ENSG00000105325 E028 156.9640501 0.0002347138 7.794008e-08 5.614013e-06 19 3534795 3538334 3540 + 2.147 2.249 0.341

Help

Please Click HERE to learn more details about the results from DEXseq.