ENSG00000105576

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000425528 ENSG00000105576 No_inf pgwt_inf TNPO2 protein_coding protein_coding 25.913 23.53037 30.39536 2.020146 0.8909168 0.3691888 2.2094948 2.753494 2.482147 0.8974392 1.2270236 -0.1491043 0.09069167 0.124575 0.083625 -0.040950 0.99284725 0.01821468 FALSE TRUE
ENST00000587155 ENSG00000105576 No_inf pgwt_inf TNPO2 protein_coding retained_intron 25.913 23.53037 30.39536 2.020146 0.8909168 0.3691888 2.0885957 2.982799 1.700401 0.7433421 1.1934547 -0.8071607 0.08222500 0.122600 0.053925 -0.068675 0.93996781 0.01821468   FALSE
ENST00000590781 ENSG00000105576 No_inf pgwt_inf TNPO2 protein_coding protein_coding 25.913 23.53037 30.39536 2.020146 0.8909168 0.3691888 1.3930298 0.000000 2.672527 0.0000000 0.6649759 8.0674488 0.04975000 0.000000 0.086575 0.086575 0.01821468 0.01821468 FALSE TRUE
MSTRG.14594.1 ENSG00000105576 No_inf pgwt_inf TNPO2 protein_coding   25.913 23.53037 30.39536 2.020146 0.8909168 0.3691888 2.5410012 2.779980 2.295636 1.7557207 0.8639522 -0.2750902 0.10436667 0.123175 0.077025 -0.046150 1.00000000 0.01821468 FALSE TRUE
MSTRG.14594.2 ENSG00000105576 No_inf pgwt_inf TNPO2 protein_coding   25.913 23.53037 30.39536 2.020146 0.8909168 0.3691888 1.7455643 2.504279 2.181818 1.1171019 0.9750501 -0.1980167 0.06450833 0.100350 0.071400 -0.028950 1.00000000 0.01821468 FALSE TRUE
MSTRG.14594.5 ENSG00000105576 No_inf pgwt_inf TNPO2 protein_coding   25.913 23.53037 30.39536 2.020146 0.8909168 0.3691888 4.3435326 0.000000 4.860963 0.0000000 2.0995531 8.9280633 0.17135833 0.000000 0.162075 0.162075 0.28809544 0.01821468 FALSE TRUE
MSTRG.14594.6 ENSG00000105576 No_inf pgwt_inf TNPO2 protein_coding   25.913 23.53037 30.39536 2.020146 0.8909168 0.3691888 5.7511980 7.127151 5.707042 0.6367762 1.1590663 -0.3200794 0.22374167 0.308475 0.188475 -0.120000 0.99284725 0.01821468 FALSE TRUE
MSTRG.14594.8 ENSG00000105576 No_inf pgwt_inf TNPO2 protein_coding   25.913 23.53037 30.39536 2.020146 0.8909168 0.3691888 0.5849986 0.000000 1.754996 0.0000000 1.7549957 7.4635208 0.01835833 0.000000 0.055075 0.055075 0.99323661 0.01821468 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000105576 E001 0.2623781 0.0160457294 0.1763715223   19 12699187 12699199 13 - 0.000 0.189 10.056
ENSG00000105576 E002 0.2454580 0.0160833423 0.8651822550   19 12699200 12699200 1 - 0.086 0.105 0.314
ENSG00000105576 E003 1.2440053 0.0160246059 0.3353900949 0.658353741 19 12699201 12699221 21 - 0.274 0.421 0.899
ENSG00000105576 E004 2.2257712 0.0977450154 0.4033769390 0.713788939 19 12699222 12699263 42 - 0.440 0.572 0.635
ENSG00000105576 E005 3.8646149 0.0120752537 0.0722004064 0.305234592 19 12699264 12699280 17 - 0.561 0.791 0.977
ENSG00000105576 E006 58.0357220 0.0058512546 0.7097262955 0.892148492 19 12699281 12699672 392 - 1.762 1.780 0.058
ENSG00000105576 E007 147.6939945 0.0001436083 0.4334040869 0.736010536 19 12699673 12701053 1381 - 2.164 2.181 0.058
ENSG00000105576 E008 8.0623233 0.0018933753 0.6967506581 0.884809833 19 12701054 12701152 99 - 0.939 0.976 0.139
ENSG00000105576 E009 15.4880350 0.0008798013 0.8022182845 0.932321027 19 12701153 12701243 91 - 1.208 1.226 0.063
ENSG00000105576 E010 11.4157827 0.0012622468 0.6969533458 0.884897252 19 12701326 12701326 1 - 1.109 1.076 -0.119
ENSG00000105576 E011 25.1733513 0.0078448463 0.7736491869 0.921222483 19 12701327 12701453 127 - 1.426 1.408 -0.065
ENSG00000105576 E012 7.8385523 0.0687321434 0.6563351363 0.865842474 19 12701598 12701598 1 - 0.916 0.976 0.223
ENSG00000105576 E013 14.7068820 0.0084406315 0.3552612538 0.675336438 19 12701599 12701644 46 - 1.158 1.233 0.266
ENSG00000105576 E014 13.1021661 0.0010635048 0.4036881828 0.714105253 19 12701645 12701672 28 - 1.117 1.182 0.233
ENSG00000105576 E015 2.0143882 0.0071421743 0.0539501143 0.259325948 19 12701673 12701751 79 - 0.322 0.602 1.451
ENSG00000105576 E016 19.4863416 0.0008521283 0.2563143263 0.583853350 19 12701752 12701851 100 - 1.274 1.348 0.259
ENSG00000105576 E017 17.8197638 0.0011528949 0.4590602908 0.753872258 19 12702072 12702147 76 - 1.299 1.247 -0.182
ENSG00000105576 E018 2.6195658 0.0726334908 0.1751913978 0.485498567 19 12702148 12702177 30 - 0.440 0.658 1.014
ENSG00000105576 E019 12.2778365 0.0049878338 0.8485533730 0.950305698 19 12702823 12702827 5 - 1.131 1.114 -0.060
ENSG00000105576 E020 22.5690517 0.0072663131 0.5289835621 0.798113026 19 12702828 12702918 91 - 1.393 1.348 -0.156
ENSG00000105576 E021 0.4733020 0.0297382781 0.4381502968   19 12702919 12703050 132 - 0.220 0.105 -1.271
ENSG00000105576 E022 18.8581341 0.0010611778 0.8634147989 0.956435073 19 12703428 12703526 99 - 1.303 1.291 -0.042
ENSG00000105576 E023 0.4738588 0.0233551561 0.4374229652   19 12703676 12703713 38 - 0.220 0.105 -1.271
ENSG00000105576 E024 13.3261512 0.0010861877 0.4420153117 0.742158485 19 12703714 12703756 43 - 1.184 1.123 -0.217
ENSG00000105576 E025 7.3725989 0.0019342737 0.4142635895 0.721773876 19 12703757 12703757 1 - 0.960 0.878 -0.311
ENSG00000105576 E026 11.1524851 0.0013068207 0.5308998761 0.799368943 19 12703758 12703801 44 - 1.109 1.056 -0.193
ENSG00000105576 E027 22.9800824 0.0007029380 0.7466267705 0.909194585 19 12705240 12705398 159 - 1.389 1.369 -0.070
ENSG00000105576 E028 0.1311489 0.0122398196 0.4315573287   19 12705399 12705490 92 - 0.000 0.105 11.672
ENSG00000105576 E029 19.6448959 0.0006636340 0.7203663848 0.897210612 19 12705492 12705599 108 - 1.303 1.326 0.080
ENSG00000105576 E030 15.7491937 0.0009146890 0.6567660076 0.865976510 19 12705682 12705768 87 - 1.208 1.240 0.112
ENSG00000105576 E031 1.6207105 0.0112688746 0.2281655400 0.553200900 19 12705769 12705830 62 - 0.322 0.503 0.992
ENSG00000105576 E032 3.5209822 0.0071279509 0.0150691728 0.120851816 19 12706010 12706109 100 - 0.474 0.791 1.392
ENSG00000105576 E033 2.2633157 0.1478745081 0.1817767349 0.494512269 19 12706110 12706195 86 - 0.365 0.631 1.314
ENSG00000105576 E034 22.7697812 0.0006106262 0.9617098969 0.990871442 19 12706196 12706367 172 - 1.377 1.374 -0.012
ENSG00000105576 E035 0.3431399 0.0275196647 0.1546789604   19 12706368 12706435 68 - 0.220 0.000 -13.478
ENSG00000105576 E036 28.5182227 0.0005100004 0.4501981755 0.747996005 19 12706570 12706795 226 - 1.489 1.447 -0.144
ENSG00000105576 E037 20.1198807 0.0006982738 0.8166965722 0.937347939 19 12710621 12710742 122 - 1.317 1.332 0.051
ENSG00000105576 E038 11.4799392 0.0012147664 0.6630628414 0.868605123 19 12710743 12710773 31 - 1.078 1.114 0.129
ENSG00000105576 E039 0.3594991 0.2173620286 0.7676050481   19 12711243 12711295 53 - 0.158 0.105 -0.686
ENSG00000105576 E040 18.9191320 0.0007557553 0.4679447204 0.759649963 19 12711296 12711426 131 - 1.322 1.273 -0.172
ENSG00000105576 E041 9.4002920 0.0021293486 0.1929320614 0.508503533 19 12711427 12711461 35 - 1.070 0.950 -0.443
ENSG00000105576 E042 10.1185053 0.0077566913 0.1844750920 0.497846344 19 12711553 12711613 61 - 1.102 0.976 -0.460
ENSG00000105576 E043 13.1636092 0.0011488327 0.2055698773 0.525314456 19 12714821 12714903 83 - 1.196 1.096 -0.360
ENSG00000105576 E044 10.7615662 0.0046567380 0.3393009302 0.661434949 19 12714904 12714939 36 - 1.109 1.023 -0.312
ENSG00000105576 E045 19.1413131 0.0122587067 0.8644263735 0.956698420 19 12715047 12715169 123 - 1.299 1.309 0.037
ENSG00000105576 E046 2.9183650 0.0048764792 0.0047549718 0.056212401 19 12715170 12715197 28 - 0.365 0.751 1.816
ENSG00000105576 E047 2.5253925 0.0315372028 0.0320608186 0.191387689 19 12715198 12715242 45 - 0.365 0.683 1.536
ENSG00000105576 E048 9.3214008 0.0592924030 0.6297685147 0.851833041 19 12715243 12715324 82 - 1.045 0.976 -0.256
ENSG00000105576 E049 5.5070386 0.0686014827 0.2103488858 0.531528915 19 12715405 12715440 36 - 0.892 0.707 -0.733
ENSG00000105576 E050 9.9123919 0.0023790581 0.3190330734 0.644304563 19 12715441 12715538 98 - 1.078 0.988 -0.330
ENSG00000105576 E051 9.5239289 0.0020246623 0.7805666499 0.924017608 19 12715633 12715709 77 - 1.010 1.034 0.091
ENSG00000105576 E052 5.1536705 0.0034059676 0.4857235418 0.771824711 19 12715710 12715710 1 - 0.749 0.828 0.314
ENSG00000105576 E053 7.8205496 0.0346886213 0.7353240879 0.903868809 19 12715711 12715739 29 - 0.928 0.963 0.133
ENSG00000105576 E054 9.9151456 0.0067584181 0.5374726619 0.803466105 19 12719029 12719097 69 - 1.010 1.066 0.207
ENSG00000105576 E055 11.2898757 0.0029450660 0.3066212252 0.633234560 19 12719098 12719178 81 - 1.045 1.132 0.314
ENSG00000105576 E056 6.6713784 0.0021535722 0.6852099072 0.879908376 19 12719261 12719266 6 - 0.905 0.862 -0.163
ENSG00000105576 E057 9.1192014 0.0015373296 0.0684949298 0.296610929 19 12719267 12719336 70 - 1.078 0.908 -0.630
ENSG00000105576 E058 10.0545824 0.0014179435 0.5114475587 0.787456281 19 12720879 12720990 112 - 1.070 1.012 -0.214
ENSG00000105576 E059 7.2735105 0.0020206754 0.0014746288 0.024079404 19 12720991 12721715 725 - 0.732 1.056 1.240
ENSG00000105576 E060 0.4923664 0.1019211376 0.8289734847   19 12722134 12722355 222 - 0.158 0.189 0.314
ENSG00000105576 E061 1.3753888 0.0092174823 0.2088266117 0.529576876 19 12722477 12722572 96 - 0.274 0.464 1.121
ENSG00000105576 E062 4.2607137 0.0447508659 0.0404623915 0.220154747 19 12723249 12723360 112 - 0.841 0.539 -1.271
ENSG00000105576 E063 2.0083379 0.1866869037 0.2317299567 0.557416126 19 12723361 12723365 5 - 0.586 0.321 -1.386
ENSG00000105576 E064 1.6161915 0.0132771810 0.0021899826 0.032510463 19 12723366 12723613 248 - 0.586 0.105 -3.387
ENSG00000105576 E065 1.8941628 0.1515517086 0.2366765264 0.561988070 19 12723769 12723772 4 - 0.560 0.321 -1.271
ENSG00000105576 E066 3.4911281 0.0064005495 0.0002958437 0.007039515 19 12723773 12724011 239 - 0.827 0.321 -2.387

Help

Please Click HERE to learn more details about the results from DEXseq.