ENSG00000105750

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000300540 ENSG00000105750 No_inf pgwt_inf ZNF85 protein_coding protein_coding 8.235771 8.045622 5.584868 0.8287734 0.5870374 -0.5258919 0.8422742 0.1192122 2.0413224 0.1192122 0.3048264 3.988740 0.13520833 0.018300 0.370950 0.352650 0.02710809 0.02710809 FALSE FALSE
ENST00000328178 ENSG00000105750 No_inf pgwt_inf ZNF85 protein_coding protein_coding 8.235771 8.045622 5.584868 0.8287734 0.5870374 -0.5258919 0.7133304 0.6547383 1.4852530 0.6547383 0.8656373 1.169531 0.12429167 0.100525 0.272350 0.171825 0.99284725 0.02710809 FALSE TRUE
ENST00000345030 ENSG00000105750 No_inf pgwt_inf ZNF85 protein_coding protein_coding 8.235771 8.045622 5.584868 0.8287734 0.5870374 -0.5258919 0.3990779 1.1972336 0.0000000 1.1972336 0.0000000 -6.915561 0.05610000 0.168300 0.000000 -0.168300 0.99853570 0.02710809 FALSE TRUE
ENST00000595742 ENSG00000105750 No_inf pgwt_inf ZNF85 protein_coding protein_coding_CDS_not_defined 8.235771 8.045622 5.584868 0.8287734 0.5870374 -0.5258919 0.6449909 1.4453232 0.4896496 1.4453232 0.4896496 -1.542351 0.09533333 0.174500 0.111500 -0.063000 1.00000000 0.02710809 FALSE TRUE
ENST00000595854 ENSG00000105750 No_inf pgwt_inf ZNF85 protein_coding protein_coding 8.235771 8.045622 5.584868 0.8287734 0.5870374 -0.5258919 0.9171205 1.5091351 0.6979302 1.1622865 0.4397347 -1.101571 0.11009167 0.153525 0.106025 -0.047500 1.00000000 0.02710809 FALSE FALSE
ENST00000596534 ENSG00000105750 No_inf pgwt_inf ZNF85 protein_coding protein_coding_CDS_not_defined 8.235771 8.045622 5.584868 0.8287734 0.5870374 -0.5258919 0.8299934 1.6994325 0.0000000 1.0309119 0.0000000 -7.417374 0.10115000 0.202275 0.000000 -0.202275 0.99284725 0.02710809 FALSE TRUE
ENST00000597314 ENSG00000105750 No_inf pgwt_inf ZNF85 protein_coding protein_coding 8.235771 8.045622 5.584868 0.8287734 0.5870374 -0.5258919 0.3971597 0.1080407 0.2285100 0.1080407 0.2285100 1.014765 0.05841667 0.010525 0.034825 0.024300 1.00000000 0.02710809 FALSE TRUE
ENST00000601284 ENSG00000105750 No_inf pgwt_inf ZNF85 protein_coding protein_coding 8.235771 8.045622 5.584868 0.8287734 0.5870374 -0.5258919 0.4482679 0.1981878 0.0000000 0.1981878 0.0000000 -4.379814 0.06091667 0.030425 0.000000 -0.030425 0.99338404 0.02710809 FALSE TRUE
MSTRG.14872.12 ENSG00000105750 No_inf pgwt_inf ZNF85 protein_coding   8.235771 8.045622 5.584868 0.8287734 0.5870374 -0.5258919 0.2003328 0.0000000 0.3450939 0.0000000 0.3450939 5.150129 0.02845000 0.000000 0.052600 0.052600 0.99284725 0.02710809 FALSE TRUE
MSTRG.14872.7 ENSG00000105750 No_inf pgwt_inf ZNF85 protein_coding   8.235771 8.045622 5.584868 0.8287734 0.5870374 -0.5258919 0.6875733 0.7513652 0.0000000 0.3138073 0.0000000 -6.250517 0.09087500 0.093650 0.000000 -0.093650 0.66556611 0.02710809   FALSE
MSTRG.14872.8 ENSG00000105750 No_inf pgwt_inf ZNF85 protein_coding   8.235771 8.045622 5.584868 0.8287734 0.5870374 -0.5258919 1.3981399 0.0000000 0.0000000 0.0000000 0.0000000 0.000000 0.06245833 0.000000 0.000000 0.000000   0.02710809 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000105750 E001 0.0000000       19 20923222 20923250 29 +      
ENSG00000105750 E002 0.0000000       19 20923251 20923252 2 +      
ENSG00000105750 E003 0.1308632 0.0123913642 7.863064e-01   19 20923253 20923275 23 + 0.000 0.080 9.593
ENSG00000105750 E004 0.1308632 0.0123913642 7.863064e-01   19 20923276 20923284 9 + 0.000 0.080 11.357
ENSG00000105750 E005 0.2454580 0.0162164974 7.730423e-01   19 20923285 20923287 3 + 0.113 0.080 -0.552
ENSG00000105750 E006 0.3769730 0.0172070597 8.426358e-01   19 20923288 20923294 7 + 0.113 0.147 0.448
ENSG00000105750 E007 0.5086348 0.0161532990 5.282476e-01   19 20923295 20923303 9 + 0.113 0.206 1.033
ENSG00000105750 E008 0.6401497 0.0157045412 3.330936e-01 6.564735e-01 19 20923304 20923309 6 + 0.113 0.257 1.448
ENSG00000105750 E009 1.3771827 0.0141267877 7.598113e-01 9.146581e-01 19 20923310 20923400 91 + 0.340 0.383 0.255
ENSG00000105750 E010 0.7370330 0.0160374195 6.544089e-01 8.652785e-01 19 20923401 20923403 3 + 0.276 0.206 -0.552
ENSG00000105750 E011 0.0000000       19 20923404 20923416 13 +      
ENSG00000105750 E012 2.8772150 0.0055508393 1.032170e-02 9.466789e-02 19 20934024 20934150 127 + 0.759 0.418 -1.552
ENSG00000105750 E013 1.0783199 0.0121228612 1.196376e-01 4.001780e-01 19 20934949 20934965 17 + 0.444 0.206 -1.552
ENSG00000105750 E014 1.1929147 0.0109806696 6.348660e-02 2.841634e-01 19 20934966 20934969 4 + 0.488 0.206 -1.775
ENSG00000105750 E015 1.2106237 0.0112221624 2.249553e-01 5.492164e-01 19 20934970 20934991 22 + 0.444 0.257 -1.137
ENSG00000105750 E016 2.1567029 0.0084479446 2.720123e-02 1.742387e-01 19 20934992 20935047 56 + 0.659 0.345 -1.552
ENSG00000105750 E017 0.1308632 0.0123913642 7.863064e-01   19 20935693 20935741 49 + 0.000 0.080 11.357
ENSG00000105750 E018 0.0000000       19 20936592 20936595 4 +      
ENSG00000105750 E019 0.0000000       19 20936596 20936605 10 +      
ENSG00000105750 E020 0.0000000       19 20936606 20936663 58 +      
ENSG00000105750 E021 0.0000000       19 20936664 20936667 4 +      
ENSG00000105750 E022 0.3425759 0.0165170117 4.882832e-02   19 20936668 20937361 694 + 0.276 0.000 -14.392
ENSG00000105750 E023 9.2180898 0.0018628520 5.975611e-07 3.564284e-05 19 20942801 20943977 1177 + 1.215 0.782 -1.609
ENSG00000105750 E024 1.1469046 0.0117203797 2.404245e-01 5.663672e-01 19 20944252 20944296 45 + 0.202 0.383 1.255
ENSG00000105750 E025 1.2437878 0.0113053659 9.589286e-01 9.900085e-01 19 20945499 20945709 211 + 0.340 0.345 0.033
ENSG00000105750 E026 1.1638899 0.0134465740 5.093275e-02 2.504154e-01 19 20946300 20946340 41 + 0.113 0.418 2.448
ENSG00000105750 E027 1.2778402 0.0125651167 1.639037e-01 4.683905e-01 19 20946341 20946389 49 + 0.202 0.418 1.448
ENSG00000105750 E028 47.3898855 0.0005521498 1.439462e-07 9.722047e-06 19 20948744 20950792 2049 + 1.574 1.719 0.494

Help

Please Click HERE to learn more details about the results from DEXseq.