ENSG00000105974

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000341049 ENSG00000105974 No_inf pgwt_inf CAV1 protein_coding protein_coding 3.018042 4.687696 2.174937 0.3281736 0.1678582 -1.104361 1.5236256 3.855072 0.0000000 0.2623934 0.0000000 -8.594351 0.39748333 0.824725 0.0000 -0.824725 2.457997e-05 2.457997e-05 FALSE TRUE
ENST00000393467 ENSG00000105974 No_inf pgwt_inf CAV1 protein_coding protein_coding 3.018042 4.687696 2.174937 0.3281736 0.1678582 -1.104361 1.3804522 0.832624 1.8330455 0.1799843 0.2132688 1.129131 0.55888333 0.175275 0.8691 0.693825 9.200955e-02 2.457997e-05 FALSE TRUE
ENST00000489856 ENSG00000105974 No_inf pgwt_inf CAV1 protein_coding retained_intron 3.018042 4.687696 2.174937 0.3281736 0.1678582 -1.104361 0.1139639 0.000000 0.3418916 0.0000000 0.3418916 5.137059 0.04363333 0.000000 0.1309 0.130900 9.928472e-01 2.457997e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000105974 E001 0.0000000       7 116524994 116525000 7 +      
ENSG00000105974 E002 0.0000000       7 116525001 116525008 8 +      
ENSG00000105974 E003 0.0000000       7 116525009 116525011 3 +      
ENSG00000105974 E004 0.0000000       7 116525012 116525035 24 +      
ENSG00000105974 E005 0.3592737 0.27361550 0.24751611   7 116525036 116525092 57 + 0.220 0.073 -1.859
ENSG00000105974 E006 0.0000000       7 116525093 116525530 438 +      
ENSG00000105974 E007 0.0000000       7 116525531 116525627 97 +      
ENSG00000105974 E008 0.0000000       7 116525628 116525783 156 +      
ENSG00000105974 E009 0.0000000       7 116525784 116525805 22 +      
ENSG00000105974 E010 0.0000000       7 116525982 116526061 80 +      
ENSG00000105974 E011 0.0000000       7 116526277 116526292 16 +      
ENSG00000105974 E012 0.2461098 0.01671534 0.51743418   7 116526293 116526388 96 + 0.124 0.073 -0.860
ENSG00000105974 E013 0.9658663 0.01387220 0.06306076 0.28308091 7 116526389 116526524 136 + 0.423 0.189 -1.597
ENSG00000105974 E014 1.0958115 0.16605773 0.15729945 0.45929259 7 116526525 116526557 33 + 0.423 0.237 -1.181
ENSG00000105974 E015 2.0944723 0.05165876 0.16391151 0.46839046 7 116526558 116526689 132 + 0.561 0.421 -0.690
ENSG00000105974 E016 0.0000000       7 116526690 116527018 329 +      
ENSG00000105974 E017 40.7529522 0.08442246 0.01016980 0.09369557 7 116558946 116561179 2234 + 1.482 1.637 0.528

Help

Please Click HERE to learn more details about the results from DEXseq.