ENSG00000107789

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000371994 ENSG00000107789 No_inf pgwt_inf MINPP1 protein_coding protein_coding 10.30304 7.683674 11.12538 0.5280668 0.6440346 0.5334057 0.951758 0.000000 1.862743 0.0000000 0.9333438 7.549009 0.0843000 0.000000 0.167800 0.167800 5.558827e-01 4.759981e-06 FALSE TRUE
ENST00000371996 ENSG00000107789 No_inf pgwt_inf MINPP1 protein_coding protein_coding 10.30304 7.683674 11.12538 0.5280668 0.6440346 0.5334057 6.756916 3.619320 8.903013 0.3289603 1.1190078 1.296214 0.6411583 0.479875 0.799125 0.319250 7.234043e-01 4.759981e-06 FALSE TRUE
ENST00000472891 ENSG00000107789 No_inf pgwt_inf MINPP1 protein_coding protein_coding_CDS_not_defined 10.30304 7.683674 11.12538 0.5280668 0.6440346 0.5334057 2.474494 4.064355 0.000000 0.7128820 0.0000000 -8.670428 0.2635083 0.520125 0.000000 -0.520125 4.759981e-06 4.759981e-06 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000107789 E001 0.4737248 0.0156583980 6.783917e-01   10 87504875 87504892 18 + 0.192 0.122 -0.777
ENSG00000107789 E002 16.6889057 0.0193968631 2.014044e-04 0.0051402654 10 87504893 87505552 660 + 1.344 1.003 -1.218
ENSG00000107789 E003 0.3427201 0.0160471761 2.753665e-01   10 87507833 87508238 406 + 0.192 0.000 -8.969
ENSG00000107789 E004 8.4273616 0.0016540916 9.842090e-02 0.3617126989 10 87508336 87508533 198 + 1.026 0.855 -0.645
ENSG00000107789 E005 5.9259793 0.0055352869 1.447932e-01 0.4403099141 10 87513124 87513221 98 + 0.895 0.717 -0.701
ENSG00000107789 E006 6.7507333 0.0045571795 7.798765e-01 0.9237246883 10 87521036 87521114 79 + 0.874 0.892 0.071
ENSG00000107789 E007 6.6364024 0.0032554150 7.038449e-01 0.8890350397 10 87521115 87521169 55 + 0.863 0.892 0.113
ENSG00000107789 E008 0.0000000       10 87546573 87546695 123 +      
ENSG00000107789 E009 71.5113014 0.0002639681 5.167233e-06 0.0002374959 10 87552082 87553461 1380 + 1.813 1.903 0.304

Help

Please Click HERE to learn more details about the results from DEXseq.