ENSG00000108175

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
MSTRG.3665.2 ENSG00000108175 No_inf pgwt_inf ZMIZ1 protein_coding   26.76404 12.70167 35.80125 0.3521055 0.3241486 1.494259 3.625706 1.965650 5.000786 0.6617758 0.7056091 1.3427094 0.1397500 0.15560 0.139550 -0.016050 1.000000000 0.002009766 FALSE TRUE
MSTRG.3665.4 ENSG00000108175 No_inf pgwt_inf ZMIZ1 protein_coding   26.76404 12.70167 35.80125 0.3521055 0.3241486 1.494259 4.485155 3.557551 5.901452 1.4533400 1.6037191 0.7285783 0.1882583 0.27635 0.163950 -0.112400 0.993312449 0.002009766 FALSE TRUE
MSTRG.3665.6 ENSG00000108175 No_inf pgwt_inf ZMIZ1 protein_coding   26.76404 12.70167 35.80125 0.3521055 0.3241486 1.494259 3.781386 0.000000 8.399001 0.0000000 1.8130676 9.7157907 0.1089250 0.00000 0.234975 0.234975 0.002009766 0.002009766 FALSE TRUE
MSTRG.3665.7 ENSG00000108175 No_inf pgwt_inf ZMIZ1 protein_coding   26.76404 12.70167 35.80125 0.3521055 0.3241486 1.494259 13.434522 6.362501 15.368864 0.9483902 3.2211617 1.2710173 0.5063333 0.50360 0.430575 -0.073025 0.992847247 0.002009766 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000108175 E001 0.3771270 1.669122e-02 0.1484931395   10 79068966 79069014 49 + 0.060 0.258 2.457
ENSG00000108175 E002 4.6571128 2.191559e-02 0.5903611108 0.832843740 10 79069015 79069270 256 + 0.698 0.768 0.287
ENSG00000108175 E003 2.7806562 1.053316e-02 0.2054472718 0.525178113 10 79118915 79119024 110 + 0.487 0.668 0.820
ENSG00000108175 E004 0.8512204 1.566330e-02 0.3626674326 0.682039352 10 79139682 79139702 21 + 0.202 0.346 1.042
ENSG00000108175 E005 3.8765627 3.730288e-03 0.0909112046 0.346280563 10 79139703 79139777 75 + 0.581 0.798 0.910
ENSG00000108175 E006 6.3783788 1.530257e-02 0.1674819385 0.474006834 10 79162053 79162133 81 + 0.780 0.940 0.617
ENSG00000108175 E007 7.7522838 3.300218e-02 0.0406706978 0.220851541 10 79201584 79201692 109 + 0.821 1.062 0.909
ENSG00000108175 E008 5.7852577 9.204741e-03 0.1165520102 0.395034976 10 79208336 79208449 114 + 0.735 0.919 0.720
ENSG00000108175 E009 5.4568636 2.440392e-02 0.9342888364 0.981826667 10 79216169 79216274 106 + 0.780 0.768 -0.046
ENSG00000108175 E010 0.2461098 1.636139e-02 0.4279636491   10 79242693 79242775 83 + 0.060 0.148 1.457
ENSG00000108175 E011 1.8423699 9.279667e-03 0.0372276682 0.209777004 10 79242776 79242969 194 + 0.507 0.148 -2.450
ENSG00000108175 E012 0.4559621 6.636545e-02 0.3268373909   10 79243669 79243738 70 + 0.202 0.000 -10.306
ENSG00000108175 E013 0.5884638 1.511984e-02 0.7744192999   10 79277179 79277180 2 + 0.202 0.148 -0.543
ENSG00000108175 E014 10.3323466 1.390285e-03 0.0003560682 0.008089698 10 79277181 79277325 145 + 1.103 0.704 -1.525
ENSG00000108175 E015 0.2277562 1.541768e-02 1.0000000000   10 79288859 79288901 43 + 0.112 0.000 -9.598
ENSG00000108175 E016 6.8284782 3.127664e-03 0.2972950649 0.625062609 10 79289775 79289889 115 + 0.892 0.768 -0.482
ENSG00000108175 E017 10.8568413 1.668382e-03 0.4011872245 0.712336109 10 79290959 79291176 218 + 1.060 0.979 -0.300
ENSG00000108175 E018 11.0639737 1.755111e-03 0.7807278445 0.924096284 10 79292158 79292356 199 + 1.037 1.062 0.091
ENSG00000108175 E019 1.7985890 8.065898e-03 0.5728105238 0.823334673 10 79293363 79293380 18 + 0.394 0.481 0.457
ENSG00000108175 E020 14.3505200 2.664025e-02 0.8160469821 0.937231601 10 79293381 79293653 273 + 1.155 1.133 -0.081
ENSG00000108175 E021 0.8691299 1.418859e-01 0.1363109657 0.427772755 10 79293654 79296470 2817 + 0.159 0.419 1.872
ENSG00000108175 E022 12.2717319 1.780474e-02 0.3630385251 0.682538066 10 79296471 79296653 183 + 1.113 1.014 -0.359
ENSG00000108175 E023 0.0000000       10 79296654 79296935 282 +      
ENSG00000108175 E024 7.3361605 1.264125e-02 0.6792563413 0.876516253 10 79297613 79297690 78 + 0.900 0.850 -0.191
ENSG00000108175 E025 10.8000082 7.091323e-03 0.9571084096 0.989458191 10 79298406 79298580 175 + 1.037 1.031 -0.024
ENSG00000108175 E026 15.2557433 3.908040e-02 0.6063729662 0.840842642 10 79299050 79299191 142 + 1.190 1.133 -0.204
ENSG00000108175 E027 19.1904370 7.863819e-04 0.6947786784 0.884018525 10 79300732 79300942 211 + 1.276 1.246 -0.104
ENSG00000108175 E028 11.4830226 1.330567e-03 0.6674883622 0.871060143 10 79302107 79302212 106 + 1.071 1.031 -0.148
ENSG00000108175 E029 16.7749272 7.931892e-04 0.3488959428 0.669564385 10 79304015 79304175 161 + 1.233 1.158 -0.267
ENSG00000108175 E030 11.6159411 1.772397e-03 0.7973456055 0.930242381 10 79305164 79305231 68 + 1.071 1.047 -0.089
ENSG00000108175 E031 17.3889080 8.034924e-04 0.0448717117 0.232509486 10 79305533 79305601 69 + 1.269 1.106 -0.580
ENSG00000108175 E032 34.9844722 6.986921e-04 0.0295624028 0.182609927 10 79306100 79306344 245 + 1.551 1.424 -0.436
ENSG00000108175 E033 19.8206117 8.143481e-04 0.9252876690 0.978989540 10 79307405 79307571 167 + 1.283 1.275 -0.026
ENSG00000108175 E034 21.3844660 1.093062e-02 0.0617047595 0.279755646 10 79310924 79311184 261 + 1.354 1.193 -0.563
ENSG00000108175 E035 680.5347094 5.497045e-05 0.0048413858 0.056847999 10 79312642 79316562 3921 + 2.788 2.807 0.064

Help

Please Click HERE to learn more details about the results from DEXseq.