ENSG00000108306

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264658 ENSG00000108306 No_inf pgwt_inf FBXL20 protein_coding protein_coding 4.739984 6.224271 3.449148 0.3242661 0.1665702 -0.849804 3.3721270 5.5283695 2.110341 0.1077909 0.1482741 -1.385165 0.68744167 0.894000 0.61870 -0.275300 0.722186435 0.002122428 FALSE TRUE
ENST00000394294 ENSG00000108306 No_inf pgwt_inf FBXL20 protein_coding protein_coding 4.739984 6.224271 3.449148 0.3242661 0.1665702 -0.849804 0.8419897 0.0000000 1.241382 0.0000000 0.2515242 6.967379 0.20324167 0.000000 0.35265 0.352650 0.002122428 0.002122428 FALSE TRUE
ENST00000581781 ENSG00000108306 No_inf pgwt_inf FBXL20 protein_coding protein_coding 4.739984 6.224271 3.449148 0.3242661 0.1665702 -0.849804 0.1584559 0.4753678 0.000000 0.2769694 0.0000000 -5.601006 0.02395833 0.071875 0.00000 -0.071875 0.992847247 0.002122428 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000108306 E001 143.7240717 0.0001577908 0.000266771 0.006487212 17 39252663 39259130 6468 - 2.058 2.126 0.228
ENSG00000108306 E002 3.1630806 0.0053189490 0.838907970 0.946409990 17 39259131 39259296 166 - 0.560 0.587 0.122
ENSG00000108306 E003 21.4683529 0.0008323759 0.003622224 0.046457938 17 39259297 39260586 1290 - 1.140 1.349 0.738
ENSG00000108306 E004 26.7553231 0.0029254597 0.001516921 0.024643281 17 39260587 39261451 865 - 1.523 1.333 -0.656
ENSG00000108306 E005 1.6024270 0.0110522422 0.222139900 0.546301241 17 39261452 39261459 8 - 0.513 0.325 -1.018
ENSG00000108306 E006 4.4858407 0.0284248092 0.288655969 0.616122825 17 39261460 39261567 108 - 0.797 0.654 -0.589
ENSG00000108306 E007 0.2631768 0.0161686890 0.728474546   17 39263876 39264174 299 - 0.000 0.120 8.845
ENSG00000108306 E008 8.1278220 0.0246008982 0.291985570 0.620089212 17 39264175 39264387 213 - 1.001 0.877 -0.468
ENSG00000108306 E009 4.0404839 0.0040618852 0.010024265 0.092854321 17 39265397 39265453 57 - 0.869 0.550 -1.328
ENSG00000108306 E010 3.5497710 0.0483697845 0.032488125 0.192958671 17 39268827 39268871 45 - 0.822 0.509 -1.340
ENSG00000108306 E011 3.8813772 0.0132676240 0.515490042 0.789900253 17 39270796 39270856 61 - 0.711 0.622 -0.378
ENSG00000108306 E012 4.4747888 0.0034900994 0.186306480 0.500228263 17 39274970 39275100 131 - 0.560 0.737 0.759
ENSG00000108306 E013 3.2092645 0.0045633887 0.082955178 0.329129938 17 39281389 39281463 75 - 0.742 0.509 -1.018
ENSG00000108306 E014 5.2037783 0.0027644826 0.075537118 0.312419068 17 39282729 39282855 127 - 0.891 0.683 -0.826
ENSG00000108306 E015 3.5999980 0.0047344528 0.191611361 0.506708740 17 39285478 39285573 96 - 0.742 0.569 -0.738
ENSG00000108306 E016 3.7505040 0.0057234053 0.430725108 0.733902644 17 39297127 39297195 69 - 0.711 0.605 -0.452
ENSG00000108306 E017 4.2070739 0.0037103531 0.081396580 0.326385593 17 39298990 39299084 95 - 0.823 0.605 -0.900
ENSG00000108306 E018 2.3941794 0.0686034367 0.862596975 0.955987955 17 39301001 39301075 75 - 0.513 0.487 -0.125
ENSG00000108306 E019 2.5749887 0.0573259719 0.160781108 0.463711304 17 39303585 39303639 55 - 0.328 0.569 1.262
ENSG00000108306 E020 2.8371566 0.0051051269 0.074729067 0.310734148 17 39343180 39343241 62 - 0.328 0.605 1.422
ENSG00000108306 E021 2.0483805 0.1197610826 0.408332399 0.717449527 17 39401361 39401656 296 - 0.328 0.487 0.875
ENSG00000108306 E022 0.0000000       17 39401666 39401706 41 -      
ENSG00000108306 E023 0.6385622 0.0404137664 0.655436550   17 39402173 39402523 351 - 0.139 0.214 0.759

Help

Please Click HERE to learn more details about the results from DEXseq.