ENSG00000108582

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000225719 ENSG00000108582 No_inf pgwt_inf CPD protein_coding protein_coding 39.27391 31.50724 47.76788 0.6589418 1.656838 0.6002017 5.669715 2.368082 9.472486 0.2962174 0.1403667 1.9954671 0.1367167 0.075075 0.198875 0.123800 5.449679e-01 3.192056e-06 FALSE TRUE
ENST00000579502 ENSG00000108582 No_inf pgwt_inf CPD protein_coding nonsense_mediated_decay 39.27391 31.50724 47.76788 0.6589418 1.656838 0.6002017 15.780041 13.936775 18.624565 0.7809137 1.3648276 0.4180496 0.4043000 0.441600 0.388375 -0.053225 9.928472e-01 3.192056e-06   FALSE
ENST00000584221 ENSG00000108582 No_inf pgwt_inf CPD protein_coding protein_coding 39.27391 31.50724 47.76788 0.6589418 1.656838 0.6002017 1.603723 4.811169 0.000000 0.3370057 0.0000000 -8.9132392 0.0508250 0.152475 0.000000 -0.152475 3.192056e-06 3.192056e-06 FALSE FALSE
MSTRG.12373.5 ENSG00000108582 No_inf pgwt_inf CPD protein_coding   39.27391 31.50724 47.76788 0.6589418 1.656838 0.6002017 15.679737 10.096360 19.510163 0.2767562 0.3519587 0.9497016 0.3940833 0.321400 0.409450 0.088050 9.928472e-01 3.192056e-06 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000108582 E001 18.8933134 6.949848e-04 1.196525e-05 4.958582e-04 17 30378927 30379615 689 + 1.384 1.047 -1.197
ENSG00000108582 E002 4.4391009 3.391800e-03 1.132640e-02 1.007665e-01 17 30379616 30379726 111 + 0.825 0.481 -1.485
ENSG00000108582 E003 0.1145948 1.120533e-02 1.000000e+00   17 30380236 30380642 407 + 0.071 0.000 -10.698
ENSG00000108582 E004 0.1316618 1.229504e-02 2.678566e-01   17 30384163 30384189 27 + 0.000 0.126 10.756
ENSG00000108582 E005 13.9901886 9.685704e-04 5.465605e-01 8.089753e-01 17 30384989 30385236 248 + 1.182 1.130 -0.183
ENSG00000108582 E006 0.0000000       17 30385237 30385292 56 +      
ENSG00000108582 E007 14.2483018 3.132344e-03 7.382241e-01 9.052334e-01 17 30420841 30420983 143 + 1.182 1.152 -0.107
ENSG00000108582 E008 16.1061298 8.537071e-04 2.016299e-02 1.448345e-01 17 30421664 30421833 170 + 1.281 1.097 -0.655
ENSG00000108582 E009 29.4344420 7.655489e-03 2.070315e-03 3.115214e-02 17 30422674 30423023 350 + 1.540 1.321 -0.758
ENSG00000108582 E010 22.7200587 1.896675e-02 2.001735e-01 5.185637e-01 17 30423506 30423697 192 + 1.403 1.284 -0.413
ENSG00000108582 E011 18.9875767 6.905489e-04 3.574491e-01 6.773835e-01 17 30427391 30427558 168 + 1.312 1.244 -0.237
ENSG00000108582 E012 12.2924614 4.079747e-02 4.822717e-01 7.692060e-01 17 30431772 30431881 110 + 1.139 1.060 -0.286
ENSG00000108582 E013 6.2110118 2.481453e-03 5.961380e-01 8.355410e-01 17 30438975 30438984 10 + 0.868 0.807 -0.240
ENSG00000108582 E014 12.2670956 1.176796e-03 2.691961e-01 5.972342e-01 17 30438985 30439077 93 + 1.145 1.047 -0.353
ENSG00000108582 E015 20.4325264 2.188400e-02 1.407066e-01 4.341751e-01 17 30442308 30442450 143 + 1.365 1.227 -0.481
ENSG00000108582 E016 22.7369515 7.891578e-03 1.482005e-02 1.195439e-01 17 30443802 30443971 170 + 1.424 1.236 -0.655
ENSG00000108582 E017 0.0000000       17 30443972 30444144 173 +      
ENSG00000108582 E018 39.6433352 3.591122e-04 1.667747e-06 8.915814e-05 17 30445691 30446020 330 + 1.675 1.421 -0.869
ENSG00000108582 E019 0.0000000       17 30447562 30447564 3 +      
ENSG00000108582 E020 19.7200572 1.255723e-03 5.077635e-02 2.499549e-01 17 30449553 30449672 120 + 1.351 1.210 -0.497
ENSG00000108582 E021 15.4826420 1.597064e-03 9.409255e-03 8.935064e-02 17 30449673 30449748 76 + 1.273 1.060 -0.760
ENSG00000108582 E022 0.0000000       17 30450236 30450294 59 +      
ENSG00000108582 E023 12.9535745 1.647647e-03 1.363199e-01 4.277737e-01 17 30451711 30451756 46 + 1.176 1.047 -0.467
ENSG00000108582 E024 16.8292737 8.283680e-04 2.258305e-02 1.556940e-01 17 30451757 30451809 53 + 1.297 1.119 -0.628
ENSG00000108582 E025 13.5004590 1.753732e-02 6.388448e-02 2.850604e-01 17 30451810 30451846 37 + 1.211 1.020 -0.689
ENSG00000108582 E026 0.0000000       17 30454021 30455338 1318 +      
ENSG00000108582 E027 24.2345572 6.188188e-04 2.558208e-02 1.680340e-01 17 30455339 30455470 132 + 1.438 1.292 -0.508
ENSG00000108582 E028 0.0000000       17 30455471 30456255 785 +      
ENSG00000108582 E029 16.4294482 8.932630e-04 8.651799e-01 9.570722e-01 17 30456256 30456324 69 + 1.234 1.219 -0.055
ENSG00000108582 E030 11.2276662 2.411780e-03 4.897854e-01 7.741794e-01 17 30456325 30456351 27 + 1.098 1.033 -0.235
ENSG00000108582 E031 16.0236805 2.673164e-03 5.493091e-01 8.105351e-01 17 30456462 30456526 65 + 1.201 1.244 0.152
ENSG00000108582 E032 0.0000000       17 30456527 30456863 337 +      
ENSG00000108582 E033 31.5074090 5.017782e-04 6.839887e-01 8.793312e-01 17 30461180 30461311 132 + 1.508 1.483 -0.087
ENSG00000108582 E034 46.9999302 1.731705e-03 1.021552e-01 3.683361e-01 17 30461877 30462062 186 + 1.697 1.615 -0.279
ENSG00000108582 E035 14.5665834 1.073365e-03 3.123248e-02 1.887421e-01 17 30462370 30462395 26 + 1.239 1.060 -0.640
ENSG00000108582 E036 23.8838476 6.845887e-03 6.473422e-02 2.871151e-01 17 30462396 30462469 74 + 1.430 1.292 -0.479
ENSG00000108582 E037 381.7083552 7.528139e-05 2.041777e-03 3.091551e-02 17 30464588 30466246 1659 + 2.554 2.594 0.133
ENSG00000108582 E038 484.3216559 5.181734e-05 9.059083e-19 2.779829e-16 17 30466247 30469989 3743 + 2.632 2.731 0.329

Help

Please Click HERE to learn more details about the results from DEXseq.