ENSG00000109171

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000264313 ENSG00000109171 No_inf pgwt_inf SLAIN2 protein_coding protein_coding 29.84379 19.91384 32.18217 4.086496 2.601438 0.6922136 9.019560 4.339774 10.673096 0.8107118 0.8889639 1.2963174 0.29763333 0.222625 0.337325 0.114700 0.9928472467 8.17133e-05 FALSE TRUE
ENST00000506375 ENSG00000109171 No_inf pgwt_inf SLAIN2 protein_coding protein_coding_CDS_not_defined 29.84379 19.91384 32.18217 4.086496 2.601438 0.6922136 7.910533 5.565447 9.018222 2.0885136 2.0411049 0.6953544 0.24933333 0.240200 0.283000 0.042800 0.9938822000 8.17133e-05 FALSE FALSE
ENST00000510595 ENSG00000109171 No_inf pgwt_inf SLAIN2 protein_coding protein_coding 29.84379 19.91384 32.18217 4.086496 2.601438 0.6922136 7.449883 3.580145 7.737150 1.6891390 2.8659520 1.1096233 0.22241667 0.148075 0.225925 0.077850 0.9932366119 8.17133e-05 FALSE TRUE
ENST00000512093 ENSG00000109171 No_inf pgwt_inf SLAIN2 protein_coding protein_coding 29.84379 19.91384 32.18217 4.086496 2.601438 0.6922136 1.035288 3.105865 0.000000 0.4547229 0.0000000 -8.2834888 0.05815833 0.174475 0.000000 -0.174475 0.0000817133 8.17133e-05 FALSE TRUE
MSTRG.21731.1 ENSG00000109171 No_inf pgwt_inf SLAIN2 protein_coding   29.84379 19.91384 32.18217 4.086496 2.601438 0.6922136 3.554117 2.498568 3.856870 0.8766597 0.8684959 0.6243024 0.14275000 0.186800 0.123425 -0.063375 1.0000000000 8.17133e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000109171 E001 1.322908 0.0215072188 8.515164e-01 9.514577e-01 4 48341499 48341528 30 + 0.376 0.346 -0.174
ENSG00000109171 E002 23.691420 0.0006617995 4.279432e-02 2.272234e-01 4 48341529 48342128 600 + 1.437 1.312 -0.433
ENSG00000109171 E003 17.706396 0.0008623390 2.701987e-03 3.780646e-02 4 48369849 48369997 149 + 1.347 1.130 -0.764
ENSG00000109171 E004 6.497763 0.0028521127 1.546208e-02 1.227730e-01 4 48377896 48377900 5 + 0.966 0.696 -1.058
ENSG00000109171 E005 22.790891 0.0056639638 1.475142e-01 4.441875e-01 4 48377901 48378060 160 + 1.411 1.312 -0.344
ENSG00000109171 E006 22.786308 0.0006495753 1.128225e-01 3.883118e-01 4 48379690 48379826 137 + 1.411 1.312 -0.344
ENSG00000109171 E007 11.391228 0.0012845164 2.676648e-01 5.959223e-01 4 48379827 48379848 22 + 1.127 1.032 -0.344
ENSG00000109171 E008 16.961215 0.0008887369 4.123456e-02 2.226109e-01 4 48382568 48382639 72 + 1.307 1.159 -0.522
ENSG00000109171 E009 17.246734 0.0008116458 1.013540e-01 3.669656e-01 4 48382640 48382727 88 + 1.302 1.186 -0.412
ENSG00000109171 E010 31.303730 0.0005368376 9.459823e-01 9.864310e-01 4 48382728 48382927 200 + 1.506 1.502 -0.012
ENSG00000109171 E011 11.856734 0.0012359284 1.009078e-01 3.660471e-01 4 48383647 48383677 31 + 1.042 1.177 0.485
ENSG00000109171 E012 22.103578 0.0007062941 9.107031e-01 9.734601e-01 4 48383678 48383784 107 + 1.362 1.355 -0.024
ENSG00000109171 E013 0.131515 0.0122322354 3.410789e-01   4 48387366 48387466 101 + 0.000 0.116 9.679
ENSG00000109171 E014 4.251101 0.0565156708 7.085787e-01 8.914496e-01 4 48394576 48394653 78 + 0.693 0.746 0.218
ENSG00000109171 E015 46.124400 0.0003992188 3.219313e-01 6.466696e-01 4 48420125 48420443 319 + 1.686 1.643 -0.146
ENSG00000109171 E016 0.245612 0.0161731360 7.327165e-01   4 48420444 48420489 46 + 0.078 0.116 0.634
ENSG00000109171 E017 246.496142 0.0001034440 4.028370e-08 3.121899e-06 4 48422011 48426201 4191 + 2.354 2.431 0.257

Help

Please Click HERE to learn more details about the results from DEXseq.