ENSG00000110768

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000265963 ENSG00000110768 No_inf pgwt_inf GTF2H1 protein_coding protein_coding 24.53675 18.45469 26.28145 0.3204144 1.390791 0.5098243 10.972646 9.2951104 9.281265 1.3443657 1.8934137 -0.0021482 0.45802500 0.503975 0.362250 -0.141725 0.99284725 0.03504981 FALSE TRUE
ENST00000418116 ENSG00000110768 No_inf pgwt_inf GTF2H1 protein_coding retained_intron 24.53675 18.45469 26.28145 0.3204144 1.390791 0.5098243 3.355164 0.2032239 5.448223 0.2032239 0.8906203 4.6779901 0.12123333 0.010900 0.203900 0.193000 0.03504981 0.03504981 FALSE TRUE
ENST00000526630 ENSG00000110768 No_inf pgwt_inf GTF2H1 protein_coding protein_coding 24.53675 18.45469 26.28145 0.3204144 1.390791 0.5098243 2.998086 3.5686757 2.503075 0.5582787 0.8490806 -0.5099719 0.13092500 0.194125 0.096725 -0.097400 0.97769704 0.03504981 FALSE FALSE
MSTRG.4501.10 ENSG00000110768 No_inf pgwt_inf GTF2H1 protein_coding   24.53675 18.45469 26.28145 0.3204144 1.390791 0.5098243 1.526461 0.0000000 4.579382 0.0000000 1.9478708 8.8421562 0.05690000 0.000000 0.170700 0.170700 0.29048962 0.03504981 FALSE TRUE
MSTRG.4501.12 ENSG00000110768 No_inf pgwt_inf GTF2H1 protein_coding   24.53675 18.45469 26.28145 0.3204144 1.390791 0.5098243 1.065626 0.9806319 0.000000 0.9806319 0.0000000 -6.6302771 0.04061667 0.052550 0.000000 -0.052550 0.99284725 0.03504981 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000110768 E001 0.5877682 0.0150827602 3.519581e-01   11 18322295 18322546 252 + 0.256 0.114 -1.423
ENSG00000110768 E002 0.0000000       11 18322547 18322556 10 +      
ENSG00000110768 E003 0.4735905 0.0303385497 5.524506e-01   11 18322557 18322566 10 + 0.204 0.114 -1.008
ENSG00000110768 E004 0.4735905 0.0303385497 5.524506e-01   11 18322567 18322567 1 + 0.204 0.114 -1.008
ENSG00000110768 E005 0.4735905 0.0303385497 5.524506e-01   11 18322568 18322568 1 + 0.204 0.114 -1.008
ENSG00000110768 E006 1.1932001 0.0121461521 5.115771e-01 0.78748221 11 18322569 18322581 13 + 0.381 0.278 -0.645
ENSG00000110768 E007 7.8125846 0.0017030091 4.367367e-01 0.73848075 11 18322582 18322740 159 + 0.974 0.896 -0.291
ENSG00000110768 E008 0.2279811 0.0153388418 4.135822e-01   11 18324236 18324296 61 + 0.146 0.000 -12.148
ENSG00000110768 E009 0.2279811 0.0153388418 4.135822e-01   11 18325947 18325969 23 + 0.146 0.000 -12.148
ENSG00000110768 E010 0.6848763 0.0141029718 3.198066e-02 0.19127146 11 18325970 18326019 50 + 0.343 0.000 -13.546
ENSG00000110768 E011 1.0784033 0.0114030114 6.793388e-01 0.87658010 11 18326020 18326153 134 + 0.343 0.278 -0.423
ENSG00000110768 E012 0.0000000       11 18332662 18333059 398 +      
ENSG00000110768 E013 5.9625543 0.0050047436 1.470789e-01 0.44348201 11 18333060 18333096 37 + 0.904 0.739 -0.645
ENSG00000110768 E014 12.2908586 0.0015053943 5.588694e-01 0.81563558 11 18333097 18333228 132 + 1.141 1.092 -0.175
ENSG00000110768 E015 0.7544717 0.0142597539 1.932129e-01 0.50885062 11 18333229 18333609 381 + 0.146 0.342 1.577
ENSG00000110768 E016 18.0802304 0.0009109360 4.863789e-01 0.77221885 11 18335754 18335946 193 + 1.298 1.249 -0.170
ENSG00000110768 E017 8.0857945 0.0017995933 3.722567e-02 0.20977700 11 18338109 18338139 31 + 1.034 0.825 -0.789
ENSG00000110768 E018 12.1748910 0.0013915961 4.202365e-02 0.22481786 11 18338140 18338216 77 + 1.183 1.012 -0.618
ENSG00000110768 E019 8.2050943 0.0018728379 7.544743e-01 0.91251301 11 18338217 18338274 58 + 0.974 0.943 -0.114
ENSG00000110768 E020 13.5295857 0.0012484815 1.059252e-01 0.37585365 11 18339564 18339657 94 + 1.210 1.082 -0.461
ENSG00000110768 E021 19.8385559 0.0007822999 1.795163e-02 0.13536654 11 18341261 18341408 148 + 1.377 1.219 -0.555
ENSG00000110768 E022 7.5997326 0.0159492191 7.639347e-01 0.91627664 11 18341409 18341410 2 + 0.945 0.913 -0.123
ENSG00000110768 E023 0.2625250 0.0161614343 1.327200e-01   11 18341411 18341527 117 + 0.000 0.204 11.968
ENSG00000110768 E024 13.3751655 0.0085481955 4.960173e-01 0.77777501 11 18341528 18341607 80 + 1.128 1.186 0.208
ENSG00000110768 E025 1.1635319 0.0109226693 2.491396e-03 0.03563951 11 18341608 18341958 351 + 0.079 0.531 3.577
ENSG00000110768 E026 1.9471615 0.0069974129 7.688930e-01 0.91872703 11 18347104 18347587 484 + 0.448 0.490 0.215
ENSG00000110768 E027 17.9564978 0.0055250051 7.969385e-02 0.32246755 11 18347588 18347715 128 + 1.327 1.195 -0.466
ENSG00000110768 E028 13.9551636 0.0028283138 4.021825e-01 0.71306948 11 18347832 18347919 88 + 1.200 1.132 -0.240
ENSG00000110768 E029 5.8819461 0.0066759135 1.445539e-03 0.02375786 11 18347920 18348831 912 + 0.644 0.999 1.397
ENSG00000110768 E030 3.2276202 0.0341382738 1.002845e-01 0.36496844 11 18351572 18351880 309 + 0.506 0.739 1.025
ENSG00000110768 E031 18.7752475 0.0007687823 1.727778e-01 0.48198436 11 18351881 18351969 89 + 1.251 1.341 0.314
ENSG00000110768 E032 0.3773519 0.0167659941 3.642040e-01   11 18352018 18352097 80 + 0.079 0.204 1.577
ENSG00000110768 E033 0.5071915 0.0229115049 1.653818e-01   11 18352098 18352328 231 + 0.079 0.278 2.162
ENSG00000110768 E034 22.3738866 0.0007116338 3.444832e-01 0.66587911 11 18352329 18352446 118 + 1.339 1.397 0.199
ENSG00000110768 E035 21.8578797 0.0038710376 7.036871e-01 0.88903504 11 18357952 18358042 91 + 1.366 1.341 -0.088
ENSG00000110768 E036 0.1315150 0.0123122726 3.552781e-01   11 18358043 18358102 60 + 0.000 0.114 11.037
ENSG00000110768 E037 23.4885965 0.0013761108 3.626006e-01 0.68203292 11 18358525 18358640 116 + 1.409 1.353 -0.195
ENSG00000110768 E038 0.0000000       11 18358641 18358642 2 +      
ENSG00000110768 E039 17.4385963 0.0007740482 2.903819e-01 0.61835665 11 18360615 18360707 93 + 1.293 1.219 -0.261
ENSG00000110768 E040 0.0000000       11 18360708 18360770 63 +      
ENSG00000110768 E041 111.3948006 0.0001491963 3.318774e-05 0.00117689 11 18365783 18367089 1307 + 2.000 2.101 0.340

Help

Please Click HERE to learn more details about the results from DEXseq.