ENSG00000111481

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000262061 ENSG00000111481 No_inf pgwt_inf COPZ1 protein_coding protein_coding 114.0393 80.82686 115.9438 3.62582 8.776929 0.520465 60.360124 57.732216 55.232607 3.331291 1.342508 -0.06384505 0.55662500 0.713525 0.485550 -0.227975 0.69965709 0.04642592 FALSE TRUE
ENST00000548076 ENSG00000111481 No_inf pgwt_inf COPZ1 protein_coding protein_coding_CDS_not_defined 114.0393 80.82686 115.9438 3.62582 8.776929 0.520465 22.063315 15.486868 14.353863 5.481100 8.350357 -0.10953290 0.18105833 0.183475 0.111750 -0.071725 0.99284725 0.04642592   FALSE
ENST00000550027 ENSG00000111481 No_inf pgwt_inf COPZ1 protein_coding retained_intron 114.0393 80.82686 115.9438 3.62582 8.776929 0.520465 22.228677 1.387647 31.478004 1.387647 4.497155 4.49373045 0.17420000 0.019825 0.270825 0.251000 0.04642592 0.04642592 FALSE FALSE
ENST00000550713 ENSG00000111481 No_inf pgwt_inf COPZ1 protein_coding protein_coding 114.0393 80.82686 115.9438 3.62582 8.776929 0.520465 2.058365 0.000000 6.175096 0.000000 4.703760 9.27265216 0.01756667 0.000000 0.052700 0.052700 0.99284725 0.04642592 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000111481 E001 0.0000000       12 54301202 54301219 18 +      
ENSG00000111481 E002 0.0000000       12 54301220 54301380 161 +      
ENSG00000111481 E003 0.0000000       12 54325083 54325108 26 +      
ENSG00000111481 E004 0.1138060 0.0110796445 6.106597e-01   12 54325109 54325128 20 + 0.089 0.000 -9.161
ENSG00000111481 E005 0.1138060 0.0110796445 6.106597e-01   12 54325129 54325130 2 + 0.089 0.000 -11.010
ENSG00000111481 E006 2.3508255 0.0075255550 1.398164e-02 1.156032e-01 12 54325131 54325138 8 + 0.664 0.314 -1.771
ENSG00000111481 E007 4.6239180 0.0030126715 7.213759e-03 7.508816e-02 12 54325139 54325143 5 + 0.878 0.562 -1.307
ENSG00000111481 E008 6.9298374 0.0020090649 1.551381e-02 1.230144e-01 12 54325144 54325150 7 + 1.002 0.761 -0.923
ENSG00000111481 E009 31.1168091 0.0027352269 7.221008e-03 7.513415e-02 12 54325151 54325181 31 + 1.570 1.431 -0.478
ENSG00000111481 E010 0.0000000       12 54325202 54325276 75 +      
ENSG00000111481 E011 0.1139502 0.0111343117 6.106017e-01   12 54325584 54325682 99 + 0.089 0.000 -11.009
ENSG00000111481 E012 0.5705569 0.0151235801 2.922339e-02   12 54340372 54340462 91 + 0.328 0.000 -13.200
ENSG00000111481 E013 0.8671147 0.0803476459 6.062356e-01 8.407604e-01 12 54340463 54340546 84 + 0.225 0.314 0.645
ENSG00000111481 E014 48.2528868 0.0018950913 8.131667e-03 8.107623e-02 12 54340547 54340615 69 + 1.742 1.635 -0.365
ENSG00000111481 E015 58.5696305 0.0003437402 3.036173e-01 6.305100e-01 12 54342206 54342287 82 + 1.788 1.761 -0.090
ENSG00000111481 E016 0.7715307 0.0432059642 7.264942e-02 3.061576e-01 12 54342288 54342630 343 + 0.089 0.367 2.551
ENSG00000111481 E017 66.1348928 0.0031965776 4.861076e-02 2.433564e-01 12 54343225 54343316 92 + 1.860 1.790 -0.235
ENSG00000111481 E018 47.4378428 0.0003003549 6.467403e-03 6.942944e-02 12 54345460 54345515 56 + 1.733 1.630 -0.353
ENSG00000111481 E019 0.0000000       12 54346612 54346674 63 +      
ENSG00000111481 E020 61.8482060 0.0002377510 8.121435e-02 3.259257e-01 12 54347767 54347844 78 + 1.823 1.771 -0.176
ENSG00000111481 E021 0.2446691 0.0159723644 9.210470e-01   12 54347845 54347972 128 + 0.089 0.102 0.229
ENSG00000111481 E022 48.6181420 0.0007551143 1.593484e-01 4.619752e-01 12 54348000 54348039 40 + 1.719 1.671 -0.163
ENSG00000111481 E023 39.0092264 0.0004128665 3.517986e-02 2.025991e-01 12 54348040 54348051 12 + 1.643 1.556 -0.296
ENSG00000111481 E024 0.7528816 0.0215483305 3.350510e-01 6.581261e-01 12 54348052 54348132 81 + 0.162 0.314 1.229
ENSG00000111481 E025 50.8334461 0.0003018331 5.421881e-01 8.063255e-01 12 54349620 54349658 39 + 1.721 1.708 -0.041
ENSG00000111481 E026 0.8156458 0.0234100844 7.385283e-02 3.086310e-01 12 54349659 54350245 587 + 0.372 0.102 -2.356
ENSG00000111481 E027 1.4874661 0.0981932726 4.804599e-01 7.679663e-01 12 54350246 54350475 230 + 0.328 0.456 0.715
ENSG00000111481 E028 425.4241651 0.0010537726 6.097029e-14 1.120095e-11 12 54350476 54351846 1371 + 2.571 2.682 0.370

Help

Please Click HERE to learn more details about the results from DEXseq.