ENSG00000111707

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360286 ENSG00000111707 No_inf pgwt_inf SUDS3 protein_coding protein_coding_CDS_not_defined 13.79595 12.51334 13.24321 0.3272415 0.5200473 0.08172228 1.297724 1.646185 1.137547 0.1682137 0.3924547 -0.5293102 0.09558333 0.13085 0.084025 -0.046825 9.928472e-01 1.385364e-05 FALSE TRUE
ENST00000541591 ENSG00000111707 No_inf pgwt_inf SUDS3 protein_coding protein_coding_CDS_not_defined 13.79595 12.51334 13.24321 0.3272415 0.5200473 0.08172228 1.709395 4.327815 0.000000 0.3651290 0.0000000 -8.7608247 0.13300833 0.34445 0.000000 -0.344450 1.385364e-05 1.385364e-05   FALSE
ENST00000543473 ENSG00000111707 No_inf pgwt_inf SUDS3 protein_coding protein_coding 13.79595 12.51334 13.24321 0.3272415 0.5200473 0.08172228 9.875604 6.365982 11.795080 0.1176309 0.3953157 0.8886884 0.71680833 0.51025 0.892700 0.382450 1.226125e-01 1.385364e-05 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgwt.inf No.inf log2fold_No.inf_pgwt.inf
ENSG00000111707 E001 1.569246 0.0092263377 6.237942e-01 8.493948e-01 12 118376555 118376560 6 + 0.445 0.370 -0.412
ENSG00000111707 E002 10.377720 0.0060587837 4.707917e-03 5.586153e-02 12 118376561 118376833 273 + 1.165 0.902 -0.964
ENSG00000111707 E003 7.893075 0.0017944151 2.580965e-02 1.690893e-01 12 118380162 118380231 70 + 1.043 0.822 -0.834
ENSG00000111707 E004 0.394040 0.0159096550 7.155064e-02   12 118383292 118383343 52 + 0.000 0.257 11.348
ENSG00000111707 E005 4.638126 0.0269124898 4.644169e-02 2.372634e-01 12 118384012 118384067 56 + 0.860 0.597 -1.082
ENSG00000111707 E006 7.224958 0.0028603487 1.794986e-01 4.918656e-01 12 118386114 118386185 72 + 0.977 0.839 -0.523
ENSG00000111707 E007 5.217348 0.0028033581 6.535855e-01 8.647684e-01 12 118389927 118389946 20 + 0.818 0.766 -0.208
ENSG00000111707 E008 13.756931 0.0190133316 1.725216e-01 4.816130e-01 12 118391126 118391282 157 + 1.227 1.098 -0.458
ENSG00000111707 E009 6.333905 0.0140291055 8.819379e-01 9.628515e-01 12 118400659 118400754 96 + 0.874 0.856 -0.068
ENSG00000111707 E010 1.571058 0.0087503605 6.222828e-01 8.485835e-01 12 118401759 118401771 13 + 0.445 0.370 -0.412
ENSG00000111707 E011 3.516548 0.0051127372 6.740546e-01 8.740105e-01 12 118401772 118401820 49 + 0.681 0.625 -0.237
ENSG00000111707 E012 4.919469 0.0043143943 1.523346e-01 4.517280e-01 12 118401983 118402004 22 + 0.847 0.677 -0.682
ENSG00000111707 E013 1.491365 0.0315974248 3.890504e-01 7.026308e-01 12 118402233 118402648 416 + 0.326 0.459 0.751
ENSG00000111707 E014 7.431716 0.0128390320 9.392327e-02 3.523769e-01 12 118403412 118403500 89 + 1.007 0.822 -0.699
ENSG00000111707 E015 3.217635 0.0116082242 1.080043e-01 3.794769e-01 12 118403501 118403517 17 + 0.719 0.498 -0.982
ENSG00000111707 E016 0.000000       12 118404056 118404473 418 +      
ENSG00000111707 E017 1.500176 0.0111290384 3.152927e-03 4.216791e-02 12 118411073 118411157 85 + 0.566 0.103 -3.319
ENSG00000111707 E018 227.719119 0.0001100297 3.876377e-09 3.587855e-07 12 118414335 118418033 3699 + 2.329 2.388 0.196

Help

Please Click HERE to learn more details about the results from DEXseq.